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A NEW CHROMOSOME BAND-SPECIFIC IDENTIFICATION METHOD

Award Information

Agency:
Department of Health and Human Services
Branch:
N/A
Award ID:
19275
Program Year/Program:
1994 / SBIR
Agency Tracking Number:
19275
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
AMERICAN LABORATORY SUPPLIES
2000 N 14TH ST, STE 530 ARLINGTON, VA 22201
View profile »
Woman-Owned: Yes
Minority-Owned: Yes
HUBZone-Owned: No
 
Phase 2
Fiscal Year: 1994
Title: A NEW CHROMOSOME BAND-SPECIFIC IDENTIFICATION METHOD
Agency: HHS
Contract: N/A
Award Amount: $426,212.00
 

Abstract:

WE WILL DEVELOP A SIMPLE CHROMOSOME BAND-SPECIFIC PAINTING TECHNIQUE, WITH THE DIRECT USE OF PCR PRODUCTS FROM MICRODISSECTED DEFINED CHROMOSOMAL REGION AS A POOL OF PROBES. THE TECNIQUE WILL BE STANDARDIZED AND WILL BE FURTHER TESTED DURING THE PHASE II PERIOD. AFTER THE TECHNIQUE/KIT IS FULLY DEVELOPED, IT WILL ALLOW THE MEDICAL PROFESSION TO IDENTIFY GENETIC ABERRRATIONS OF NEWBORNS; TO STUDY NEUROMUSCULAR DISORDERS; AND HAVE BETTER UNDERSTANDINGS WITH DISEASES SUCH AS PARKINSON'S, HUNTINGTON'S AND ALZHEIMER'S DISEASES. THIS NEW TECHNIQUE WILL ENABLE THE RESEARCH SCIENTISTS TO STUDY THE ORIGIN OF CYTOGENETICALLY UNIDENTIFIABLE MARKER CHROMOSOMES AS WELL. OUR NEW METHOD WILL PROVIDE US THE MEANS TO CONSTRUCT PROBES THAT ARE SPECIFIC FOR EVERY METAPHASE CHROMOSOME BAND OF THE HUMAN GENOME, AND TO GENERATE BAND-SPECIFIC PROBE POOL IN LESS THAN TWO DAYS. THE USE OF OUR TECHNIQUE/PRODUCT PERTAINS TO STUDY OF GENETIC DISEASES OF THE NEWBORNS AND CHILDREN, AS WELL AS THE DIAGNOSIS OF COMMON DISEASES OF THE AGED. THE FUTURE MARKETING POSSIBLE IS UNLIMITED, WORLDWIDE.

Principal Investigator:

Han-xiang Deng
7035583400

Business Contact:

Small Business Information at Submission:

C P Li Biomedical
2000 North 14th Street Suite 740 Arlington, VA 22201

EIN/Tax ID:
DUNS: N/A
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No