The primary objective of the proposed program is the ultimate development of a practical wearable air power supply for an implanted pneumatic artificial heart. the proposal addresses itself to the concept of a wearable power supply for a pneumatic heart that has been implanted in an ambulatory… More

Many patients with chronic respiratory failure require indefinite mechanical ventilatory assistance to sustain life. patients treated at home, as well as hospitalized patients, are restricted to a bed-to-chair existence because of the size of existing mechanical ventilatory equipment. the… More

There is need for a two-phase flowmeter to measure mass flowrate of each phase of liquid/vapor flow in conduits for launch propellant management. a great variety and combinations of flow measuring devices and methods have been used for two-phase flow, including vibratory tubular true mass… More

There is need for a miniature, non-gravity-dependent infusion device that is sufficiently small and light to be used as a wearable unit. one important application for a wearable infusion device is for total parenteral nutrition. the availability of a reliable, wearable infusion device could free… More

Hemofiltration is increasingly used as a treatment of patients with acute renal failure and an alternative to dialysis. an infusion device must provide substitution fluid at a controlled lower rate than that of liquid removal for net reduction of body water. hemofilter use is limited by decrease in… More

The goal of the phase ii program is the development of a prototype, battery-operated, wearable air supply for pneumatically operated, implanted artificial hearts. the ultramin-iatureized air supply is dessigned to be worn by ambulatory patients with implanted, pneumatic total artificial hearts or… More

Beta agonists administered in aerosol form is one of the most potent and widely used bronchodilator therapies. in hospitals, beta agonists are usually administered by compressed air nebulizers. numerous studies have documentedthe efficacy of the bronchodilator aerosol delivered from a canister… More

There is a need for a miniature blower to be used to reduce thermal stress, protect respiration and inhibit fogging in nuclear, biological, chemical (nbc) protective masks. an optimally small and light blower compatible with delivery requirements is desirable. to minimize battery weight, maximum… More

Circulatory assist devices are needed for immediate temporary treatment of acute myocardial infarction and for some postcardiotomy patients. implanted circulatory assist devices also are being developed for longer term help to ambulatory patients with chronic heart failure. pneumatic and… More

Circulatory assist devices are needed for immediate temporary treatment of acute myocardial infarction and for some postcardiotomy patients. since more than 30 years ago, the efforts of a number of reseachers and clinicians have resulted in the now widely used counterpulsation intra-aortic balloon… More

Personal sampler pumps are worn by industrial workers to determine the concentration of particulates to which the worker has been exposed during a work shift. usually a particulate collection device, such as a filter, is worn in the breathing zone of the worker and connected to a belt-mounted pump… More

Mechanical circulatory assist devices are being developed for medium-term and long-term help to ambpatients with chronic heart failure, as well as for immediate temporary treatment of acute myocardiapostcardiotomy patients. In recent years there hash been increasing development of continuous flow… More

Not Available A feasibility study is proposed for a practical, fast, high-accuracy hyperspectral x-ray detector system for detection and imaging of objects such as energetic materials and contraband. It may have many other uses such as finding and identifying contraband in luggage, briefcases,… More

The ability to detect and analyze rare malignant cells in body fluids has profound implications for the early detection of malignancy as well as for monitoring of residual disease and metastases. Current methodologies for accurately detecting abnormal cells within a population of normal cells are… More

Proposed is the development the extended depth of field (EDF) or confocal like imaging capabilities of a breakthrough multispectral high resolution imaging flow cytometer. This platform shall have unparalleled cellular analysis capabilities intended to further biological space research (fundamental,… More

Proposed is the development the extended depth of field (EDF) or confocal like imaging capabilities of a breakthrough multispectral high resolution imaging flow cytometer. This platform shall have unparalleled cellular analysis capabilities intended to further biological space research (fundamental,… More