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COMPOSITE, HOLLOW FIBER MEMBRANE OXYGENATION DEVICE

Award Information

Agency:
Department of Health and Human Services
Branch:
N/A
Award ID:
7304
Program Year/Program:
1989 / SBIR
Agency Tracking Number:
7304
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
ANATRACE, INC.
ANATRACE, INC. 26111 Miles Rd Cleveland, OH 44128 5933
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Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 2
Fiscal Year: 1989
Title: COMPOSITE, HOLLOW FIBER MEMBRANE OXYGENATION DEVICE
Agency: HHS
Contract: N/A
Award Amount: $461,350.00
 

Abstract:

THE ACCEPTANCE OF EXTRACORPOREAL OXYGENATION DEVICES BASED ON GAS TRANSFER THROUGH A MEMBRANE WILL DEPEND TO A LARGE EXTENT ON THE AVAILABILITY OF SIMPLER, EASIER TO USE, SAFER,AND LOWERCOST DEVICES. OXYGENATORS USING MICROPOROUS HOLLOWFIBERS HAVE COME INTO WIDER USE THE LAST FIVE YEARS. THEY PRESENT MORE MEMBRANE SURFACE TO BLOOD AND GAS PHASES FOR EQUIVALENT VOLUME AND DO NOT REQUIRE A SUPPLEMENTAL SECONDARY FLOW FOR ADEQUATE GAS TRANSFER. THESE DEVICES DO,HOWEVER, SUFFER FROM THE REAL AND POTENTIAL PROBLEMS ASSOCIATED WITH ALL MEMBRANE OXYGENATORS MADE FROM MICROPOROUS MATERIALS-POSSIBLE BLOOD DAMAGE DUE TO MICROBUBBLE INTRUSION, EXCESSIVE WATER TRANSPORT AND SEEPAGE, AND A LACK OF SELECTIVITY IN EXCHANGING OXYGEN AND CARBON DIOXIDE. THIS PROPOSAL SUGGESTS AN IMPROVEMENT TO THE PRESENT STATE-OF-THE-ART, MICROPOROUS-BASED HOLLOW-FIBER OXYGENATORSTHAT ELIMINATES ALL THE ABOVE PROBLEMS BY DEVELOPING A COMPOSITE PERMSELECTIVE/MICROPOROUS HOLLOW FIBER DEVICE OF OPTIMUM GEOMETRY AND MEMBRANE CHARACTERISTICS. THE OPTIMIZED HOLLOW-FIBER GEOMETRY WILL BE COMBINED WITH PAS MATERIALS THAT HAVE BEEN SHOWN TO HAVE SUPERIOR PERMEABILITYTO CARBON DIOXIDE AND OXYGEN AND HIGH BIOCOMPATIBILITY WITH BLOOD.

Principal Investigator:

Don N Gray Phd
4198913030

Business Contact:

Small Business Information at Submission:

Anatrace Inc.
1280 Dussel Drive Maumee, OH 43537

EIN/Tax ID:
DUNS: N/A
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No