USA flag logo/image

An Official Website of the United States Government

Synthesis & Characterization of a Tuberculosis Vaccine

Award Information

Agency:
Department of Health and Human Services
Branch:
N/A
Award ID:
71184
Program Year/Program:
2004 / SBIR
Agency Tracking Number:
AI056880
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
ANCORA PHARMACEUTICALS, INC.
ANCORA PHARMACEUTICALS, INC. 200 BOSTON AVENUE, STE 4975 MEDFORD, MA 99999-
View profile »
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 1
Fiscal Year: 2004
Title: Synthesis & Characterization of a Tuberculosis Vaccine
Agency: HHS
Contract: 1R43AI056880-01A1
Award Amount: $133,000.00
 

Abstract:

DESCRIPTION (provided by applicant): Tuberculosis (TB) has plagued mankind for millennia. While several drugs and vaccine strategies have been developed to counter the TB, it remains a major infectious cause of morbidity and mortality worldwide. 1.Though the elucidation of the M. tuberculosis genome may yield novel drug targets, an efficacious vaccine strategy is key to controlling this infectious disease. 2. Recent research describing the immunopathology of TB infection and the innate immune system reveals a novel vaccination approach utilizing non-peptide based antigens. 3. Glycolipid-based molecules demonstrate the ability to generate a strong, cell mediated immune response, which is thought to be critical against M. tuberculosis. A predominant M. tuberculosis glycolipid molecule, lipoarabinomannan (LAM), also can elicit a strong immune response. The goal of this SBIR proposal will be to generate synthetic LAM-derived, glycolipid-based, molecules that can serve as potential TB vaccine candidates.

Principal Investigator:

Obadih J. Plante
7813957700
OPLANTE@ANCORAPHARMA.COM

Business Contact:

John Pena
6173540863
JPENA@ANCORAPHARMA.COM
Small Business Information at Submission:

ANCORA PHARMACEUTICALS
ANCORA PHARMACEUTICALS 700 HURON AVE, #18K CAMBRIDGE, MA 02138

EIN/Tax ID: 470877050
DUNS: N/A
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No