DESCRIPTION (provided by applicant): The real-time polymerase chain reaction (PCR) is the most commonly used method for quantitative gene expression profiling; it allows extremely sensitive measurement of hundreds of mRNA transcripts in parallel. We propose a method by which protein abundances can… More
Award Year / Program / Phase:2006 / SBIR / Phase II
Agency:HHS
Principal Investigator:Huangtsu Chen
Award Amount:$978,045.00
Abstract:
DESCRIPTION (provided by applicant): Numerous proteomics platforms for measuring multiple proteins in parallel have been developed, but adoption has been limited by the fact that they all are orders of magnitude less sensitive than standard ELISA assays. By contrast, methods for quantitatively… More
Award Year / Program / Phase:2008 / SBIR / Phase I
Agency:HHS
Principal Investigator:
Award Amount:$194,424.00
Abstract:
DESCRIPTION (provided by applicant): Site-specific protein phosphorylation is essential for signal transduction in mammalian cells, and perturbation in phosphoprotein levels is a hallmark of cancerous transformation. Unfortunately there are no sensitive me
thods for detecting multiple… More