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Circulating Prostate Cancer Progenitor Cell Assay Development

Award Information

Agency:
Department of Defense
Branch:
Army
Award ID:
85077
Program Year/Program:
2008 / STTR
Agency Tracking Number:
A08A-041-0388
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
ANDROBIOSYS, INC.
875 Ellicott St BUFFALO, NY 14203-1070
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Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 1
Fiscal Year: 2008
Title: Circulating Prostate Cancer Progenitor Cell Assay Development
Agency / Branch: DOD / ARMY
Contract: W81XWH-08-C-0099
Award Amount: $96,765.00
 

Abstract:

This Phase I contract proposal will evaluate and identify markers associated with prostate cancer progenitor stem cells, that differentiate these cells from adult tissue stem cells and benign prostate progenitor cells. The eventual goal of this work would be to develop a high throughput blood-based assay highly specific for circulating prostate cancer progenitor cells. A cell shed from a tumor must be capable of surviving separate from the microenvironment of the primary tumor, and possess the capacities of proliferation and plasticity, to regenerate a metastasis. These traits essentially describe a cancer stem cell (CSC). Therefore, we propose to develop a technology to identify circulating CSCs, or more accurately the progenitor cells that are their immediate progeny, an approach that should provide a more informative prognostic tool for prediction of aggressiveness and metastatic potential.

Principal Investigator:

Michael Zwick
CEO
7168607920
mzwick@androbiosys.com

Business Contact:

Michael Zwick
CEO
7168607920
mzwick@androbiosys.com
Small Business Information at Submission:

ANDROBIOSYS, INC.
73 High Street Buffalo, NY 14203

EIN/Tax ID: 202315778
DUNS: N/A
Number of Employees:
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
Research Institution Information:
ROSWELL PARK CANCER INSTITUTE
Elm and Carlton Streets
Buffalo, NY 14263
Contact: Joseph H. Jurkowski
Contact Phone: (716) 845-2312
RI Type: Domestic nonprofit research organization