USA flag logo/image

An Official Website of the United States Government

SBIR Phase I: Manufacturing and Testing of Nanocrystalline Hydroxyapatite…

Award Information

National Science Foundation
Award ID:
Program Year/Program:
2003 / SBIR
Agency Tracking Number:
Solicitation Year:
Solicitation Topic Code:
Solicitation Number:
Small Business Information
Angstrom Medica, Inc.
Angstrom Medica, Inc. 150 -A New Boston St Woburn, MA 01801
View profile »
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
Phase 1
Fiscal Year: 2003
Title: SBIR Phase I: Manufacturing and Testing of Nanocrystalline Hydroxyapatite Orthopedic Implants
Agency: NSF
Contract: 0319936
Award Amount: $100,000.00


This Small Business Innovation Research (SBIR)Phase I project proposes to develop forming and sintering processes suitable for the manufacture of nanocrystalline hydroxyapatite orthopedic implants. Though hydroxyapatite's osteoconductivity has generated interest in many clinical applications, conventionally processed hydroxyapatite materials have been limited by their poor sinterability and lack of mechanical strength attributed to poor phase purity and homogeneity. Angstrom Medica, Inc. has optimized its nanostructure hydroxyapatite powders for sinterability, mechanical strength and nanocrystallinity. The nanocrystalline HAP monoliths appear to provide superior compressive and bending strengths as well as fracture toughness, and contribute to better osteoblast attachment, proliferation and mineralization. This project will conduct the early process and product development of a marketable nanocrystalline HAP orthopedic pin for small bone fixation and the testing of this pin in a cadaver bone model. In the follow on Phase II project, these nanostructured materials will be formed into more geometrically complex implants constructs and utilized in in vivo animal models commonly employed to validate orthopedic implants for FDA approval. The commercial application of this project is in the area of orthopedic implants.

Principal Investigator:

Edward Ahn

Business Contact:

Small Business Information at Submission:

Angstrom Medica, Incorporated
150 California Street Newton, MA 02458

Number of Employees:
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No