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Development of APMS as a Chromatographic Substrate

Award Information

Agency:
Department of Health and Human Services
Branch:
N/A
Award ID:
76263
Program Year/Program:
2005 / STTR
Agency Tracking Number:
GM071059
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
APOLLO SRI, LLC
APOLLO SRI, LLC 210 COLCHESTER AVE BURLINGTON, VT 05405
View profile »
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 1
Fiscal Year: 2005
Title: Development of APMS as a Chromatographic Substrate
Agency: HHS
Contract: 1R41GM071059-01A1
Award Amount: $100,000.00
 

Abstract:

DESCRIPTION (provided by applicant): Acid-prepared mesoporous silica ("APMS") shows significant advances over commercially available silica in high performance liquid chromatography ("HPLC"), a technique commonly used to isolate molecules. HPLC columns containing APMS show dramatically enhanced molecular retention times and improved peak-to-peak resolutions compared to commercial HPLC columns. These benefits are due to the physical properties of APMS, which consists of regular 5 um spheres with a surface area of 1100 m2/g. The proposed research has three main goals: (1) to initiate studies on larger-scale production of APMS; (2) to expand previous studies on chiral separations; and (3) to study the potential uses of APMS in size-exclusion chromatography. The ultimate goal of this research will be to produce a suite of HPLC column materials. The HPLC columns market is $500M and growing at 8% annually. Because HPLC is a standard research tool, successful commercialization of APMS will benefit society and researchers by accelerating the major advances in understanding fundamental life processes. In particular, APMS could facilitate liquid chromatography-mass spectrometry (LC-MS), size exclusion chromatography (SEC), and chiral separations.

Principal Investigator:

Christopher C. Landry
8026560270
CHRISTOPHER.LANDRY@UVM.EDU

Business Contact:


8325673593
Small Business Information at Submission:

Apollo Sri, LLC
Apollo Sri, Llc 173 Staniford Rd Burlington, VT 05401

EIN/Tax ID: 010776976
DUNS: N/A
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
Research Institution Information:
UNIVERSITY OF VERMONT
85 SOUTH PROSPECT STREET
340 WATERMAN BUILDING
BURLINGTON, VT 05405
RI Type: Nonprofit college or university