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STATISTICAL DETECTION OF CANCER CLUSTERS

Award Information

Agency:
Department of Health and Human Services
Branch:
N/A
Award ID:
13697
Program Year/Program:
1991 / SBIR
Agency Tracking Number:
13697
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
Applied Biomathematics
100 North Country Rd. Setauket, NY -
View profile »
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 2
Fiscal Year: 1991
Title: STATISTICAL DETECTION OF CANCER CLUSTERS
Agency: HHS
Contract: N/A
Award Amount: $433,331.00
 

Abstract:

THE ACCURATE DETECTION OF DISEASE CLUSTERS IS A WELL-ACKNOWLEDGED PROBLEM. FALSE DETECTIONS MAY BE EXPECTEDUNDER REPETITIVE TESTING, BUT THE OPPOSITE SITUATION, THAT OF FAILING TO DETECT CLUSTERS WHEN THEY ACTUALLY EXIST,IS INCREASINGLY RECOGNIZED. BOTH FALSE DETECTIONS AND FAILURES TO DETECT HAVE STRIKING IMPLICATIONS FOR EPIDEMIOLOGICAL STUDIES, BECAUSE SPACE-TIME CLUSTERING IS OFTEN A FIRST STEP IN THE ANALYSIS OF SUSPECTED PUBLIC HEALTH PROBLEMS. THE FAILURE TO FIND EXISTING CLUSTERS MEANS THAT REAL DISEASE CLUSTERS WILL BE IGNORED, BUT FALSE DETECTIONS RESULT IN A LOSS OF PUBLIC CONFIDENCE AND WASTED RESOURCES. CLEARLY, STUDIES ARE REQUIRED TO ACCURATELY DETERMINE THE ABILITIES OF SPACE-TIME CLUSTERING METHODS UNDER DIFFERENT SPATIAL AND TEMPORAL PATTERNS OF DISEASE INCIDENCE. THE OBJECTIVES OF THIS PROJECT ARE (1) TO DETERMINE THE ABILITY OF EXISTING METHODS TO DETECT CANCER CLUSTERS, AND (2) TO DEVELOP NOVEL, SENSITIVE APPROACHES TO THE DETECTION OF DISEASE CLUSTERS IN SITUATIONS WHERE ENVIRONMENTAL AND GEOGRAPHIC CAUSES ARE SUSPECTED. A USER-FRIENDLY, INTERACTIVE, PC PROGRAM CALLED CLUSTER ANALYSIS IN SPACE AND TIME (CAST) WILL BE DEVELOPED IN PHASE I. THE PROGRAM SERVES TWO PURPOSES: (1) CLUSTER DESCRIPTION THROUGH INTERACTIVE MAPPING AND GRAPHICS, AND (2) CLUSTER DETECTION USING SOPHISTICATED STATISTICAL TECHNIQUES. CAST WILL SERVEAS A BASIS FOR THE PHASE II RESEARCH, WHICH WILL DETERMINE THE SENSITIVITY OF EXISTING CLUSTER DETECTION TECHNIQUES ANDDEVELOP NEW CLUSTER DETECTION METHODOLOGIES.

Principal Investigator:

Geoffrey M Jacquez
5167514350

Business Contact:

Small Business Information at Submission:

Applied Biomathematics Inc.
100 N Country Rd Setauket, NY 11733

EIN/Tax ID: 112596502
DUNS: N/A
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No