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Company Information:

Company Name: APPLIED BIOPHYSICS, INC.
City: TROY
State: NY
Zip+4: 12180
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
Website URL: N/A
Phone: N/A

Award Totals:

Program/Phase Award Amount ($) Number of Awards
SBIR Phase I $247,774.00 4
SBIR Phase II $2,387,580.00 4
STTR Phase I $100,000.00 2
STTR Phase II $243,956.00 1

Award List:

ELECTRODE ARRAYS IN TISSUE CULTURE

Award Year / Program / Phase: 1991 / SBIR / Phase I
Agency: HHS
Principal Investigator: Charles Keese
Award Amount: $49,950.00

AN ELECTRICAL APPROACH FOR IN VITRO TOXICOLOGY

Award Year / Program / Phase: 1992 / SBIR / Phase I
Agency: HHS
Principal Investigator: Charles R Keese
Award Amount: $50,000.00

ELECTRICAL MEASUREMENT OF CELL MOTILITY IN VITRO

Award Year / Program / Phase: 1992 / SBIR / Phase I
Agency: HHS
Principal Investigator: Charles R Keese
Award Amount: $49,998.00

ELECTRODE ARRAYS IN TISSUE CULTURE

Award Year / Program / Phase: 1993 / SBIR / Phase II
Agency: HHS
Principal Investigator: Charles Keese
Award Amount: $486,623.00
Abstract:
The goal of this project is to develop an array of 10-(4)cm(2) electrodes for use with a new instrumental method for tissue culture. the method, referred to as ecis (electric cell-substrate impedance sensor), is a non-invasive technique to measure several in vitro cell parameters that have… More

ELECTRICAL MEASUREMENT OF CELL MOTILITY IN VITRO

Award Year / Program / Phase: 1994 / SBIR / Phase II
Agency: HHS
Principal Investigator: Charles R Keese
Award Amount: $549,000.00
Abstract:
We have been developing an instrument that electrically detects cell motion in tissue culture and intend to make a commercial device suitable for the medical/biological research market. the immediate challenge is to relate motion of cells measured by this method to other recognized cellular… More

AN ELECTRICAL APPROACH FOR IN VITRO TOXICOLOGY

Award Year / Program / Phase: 1996 / SBIR / Phase II
Agency: HHS
Principal Investigator: Charles R Keese
Award Amount: $601,963.00
Abstract:
We have been developing a new means to electrically study animal cells grown in tissue culture and intend to make a commercial device suitable for use in the medical/biological reseach and testing market. the instrumental method, referred to as ecis (electric cell-substrate impedance sensor), is a… More

N/A

Award Year / Program / Phase: 2000 / STTR / Phase I
Agency: HHS
Research Institution: University of Connecticut
Principal Investigator:
Award Amount: $100,000.00
RI Contact: N/A

Automated Monitoring of Chemotactic Cell Movement

Award Year / Program / Phase: 2001 / STTR / Phase I
Agency: HHS
Research Institution: UNIVERSITY OF CONNECTICUT
Principal Investigator: Michael A. Lynes
Award Amount: $0.00
RI Contact: N/A
Abstract:
DESCRIPTION ( provided by applicant): The ECIS/taxis technology can detect cells that move to a small electrode through an agarose matrix by the resistance that they impart to an electrical circuit as they cover parts of the small electrode. This system is amenable to… More

ECIS-based High Throughput Screening Instrumentation

Award Year / Program / Phase: 2005 / SBIR / Phase I
Agency: HHS
Principal Investigator: Charles R. Keese
Award Amount: $97,826.00
Abstract:
DESCRIPTION (provided by applicant): Electric Cell-substrate Impedance Sensing (ECIS) was developed by Applied Bio Physics to study the behavior of cultured cells in real time. Instruments currently find use in over 60 laboratories world wide measuring cell properties such as permeability of cell… More

ECIS-based High Throughput Screening Instrumentation

Award Year / Program / Phase: 2008 / SBIR / Phase II
Agency: HHS
Principal Investigator:
Award Amount: $749,994.00
Abstract:
DESCRIPTION (provided by applicant): The long-term objective of the research is to develop and fabricate an instrument that can facilitate the discovery of new drugs via high throughput screening (HTS). ECIS (electric cell-substrate impedance sensing) is a technology developed by Applied BioPhysics… More