Award Year / Program / Phase:1993 / SBIR / Phase II
Agency:HHS
Principal Investigator:Charles Keese
Award Amount:$486,623.00
Abstract:
The goal of this project is to develop an array of 10-(4)cm(2) electrodes for use with a new instrumental method for tissue culture. the method, referred to as ecis (electric cell-substrate impedance sensor), is a non-invasive technique to measure several in vitro cell parameters that have… More
Award Year / Program / Phase:1994 / SBIR / Phase II
Agency:HHS
Principal Investigator:Charles R Keese
Award Amount:$549,000.00
Abstract:
We have been developing an instrument that electrically detects cell motion in tissue culture and intend to make a commercial device suitable for the medical/biological research market. the immediate challenge is to relate motion of cells measured by this method to other recognized cellular… More
Award Year / Program / Phase:1996 / SBIR / Phase II
Agency:HHS
Principal Investigator:Charles R Keese
Award Amount:$601,963.00
Abstract:
We have been developing a new means to electrically study animal cells grown in tissue culture and intend to make a commercial device suitable for use in the medical/biological reseach and testing market. the instrumental method, referred to as ecis (electric cell-substrate impedance sensor), is a… More
DESCRIPTION ( provided by applicant): The ECIS/taxis technology can detect
cells that move to a small electrode through an agarose matrix by the
resistance that they impart to an electrical circuit as they cover parts of the
small electrode. This system is amenable to… More
DESCRIPTION (provided by applicant): Electric Cell-substrate Impedance Sensing (ECIS) was developed by Applied Bio Physics to study the behavior of cultured cells in real time. Instruments currently find use in over 60 laboratories world wide measuring cell properties such as permeability of cell… More
Award Year / Program / Phase:2008 / SBIR / Phase II
Agency:HHS
Principal Investigator:
Award Amount:$749,994.00
Abstract:
DESCRIPTION (provided by applicant): The long-term objective of the research is to develop and fabricate an instrument that can facilitate the discovery of new drugs via high throughput screening (HTS). ECIS (electric cell-substrate impedance sensing) is a
technology developed by Applied BioPhysics… More