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Novel Detergents for Membrane Proteins

Award Information

Agency:
Department of Health and Human Services
Branch:
N/A
Award ID:
29372
Program Year/Program:
1995 / SBIR
Agency Tracking Number:
29372
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
APPLIED BIOTECH CONCEPTS, INC.
25 SCIENCE PARK NEW HAVEN, CT 06511
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Woman-Owned: No
Minority-Owned: Yes
HUBZone-Owned: No
 
Phase 1
Fiscal Year: 1995
Title: Novel Detergents for Membrane Proteins
Agency: HHS
Contract: 1 R43 DK48687-01,
Award Amount: $80,184.00
 

Abstract:

Crystallization of membrane-proteins has been a difficult problem because of their peculiar physiconature. We will develop detergents that closely mimic the biological milieu inhabited by membrane prdetergents are expected to form large micelles; thereby, allowing the formation of larger, and hopefcrystals than the presently used detergents. Two families of novel detergents will be synthesized, pchemically characterized,. A few selected detergents will then be tested at the Lawrence Berkeley Lab/c1 complex and PhoE Porin for the ability to promote crystallization and the type, size and diffraformed.

Principal Investigator:

Anil Diwan
20386

Business Contact:

Small Business Information at Submission:

Applied Biotech Concepts, Inc.
25 Science Park New Haven, CT 06511

EIN/Tax ID:
DUNS: N/A
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No