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Mouse Chromosome-Specific Painting Probes

Award Information

Agency:
Department of Health and Human Services
Branch:
N/A
Award ID:
22291
Program Year/Program:
1995 / SBIR
Agency Tracking Number:
22291
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
APPLIED GENETICS LABORATORIES
1335 GATEWAY DR, STE 2001 MELBOURNE, FL 32904
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Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 2
Fiscal Year: 1995
Title: Mouse Chromosome-Specific Painting Probes
Agency: HHS
Contract: N/A
Award Amount: $735,111.00
 

Abstract:

We have described a new technology called "preparative in situ hybridization (Prep-I.S.H.), which is capable of isolating a set of cDNA or genomic clones according to their chromosome location. The technology takes advantage of in situ hybridization of cloned DNAs to metaphase chromosome spreads, chromosome microdissection, and the polymerase chain reaction (PCR). We will use this technology to develop a set of chromosome-specific painting probes for the mouse. The demonstration case, a chromosome 11-specific probe, will be used to paint the mitotic chromosome 11s derived from the mouse lymphoma assay (MLA).

Principal Investigator:

Melissa C. Liechty
4077682048

Business Contact:

Small Business Information at Submission:

Applied Genetics
1335 Gateway Dr. Melbourne, FL 32901

EIN/Tax ID:
DUNS: N/A
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No