USA flag logo/image

An Official Website of the United States Government

Three-Dimensional Optical Coherence Tomography (3D OCT)

Award Information

National Aeronautics and Space Administration
Award ID:
Program Year/Program:
2005 / SBIR
Agency Tracking Number:
Solicitation Year:
Solicitation Topic Code:
Solicitation Number:
Small Business Information
Applied Science Innovations, Inc.
185 Jordan Road Troy, NY 12180
View profile »
Woman-Owned: Yes
Minority-Owned: No
HUBZone-Owned: No
Phase 2
Fiscal Year: 2005
Title: Three-Dimensional Optical Coherence Tomography (3D OCT)
Agency: NASA
Contract: NNC05CA08C
Award Amount: $599,988.00


Applied Science Innovations, Inc. proposes a new tool of 3D optical coherence tomography (OCT) for cellular level imaging at video frame rates and dramatically reduced probe cross-section. Existing commercial OCT tools are focused in ophthalmology, where examination is external to the eye, the size of the probe is not important, and cellular level resolution is not required. The patent-pending 3D OCT will provide three-dimensional imaging in scattering media with improved resolution, depth of field, and minimal mechanical adjustment. The proposed approach is based on novel probe designs, original coherence scanning, and advanced signal processing. The flexible imaging probe will have dramatically reduced cross-section, compared to the existing systems, enabling the first "3D camera through a needle" for functional imagery, including in-vivo histological examination. Phase I has demonstrated the proof of concept by theoretical studies and implementation of a limited experimental prototype. First generation packaged prototype will be developed in Phase II of the project and delivered to NASA Glenn Research Center for evaluation and field tests. Commercial applications are envisioned in NASA's future space missions, biomedical imaging, and industrial inspection.

Principal Investigator:

Mikhail A. Gutin
Principal Investigator

Business Contact:

Mikhail A. Gutin
Small Business Information at Submission:

Applied Science Innovations, Inc.
1223 Peoples Ave Troy, NY 12180

EIN/Tax ID: 113665143
Number of Employees:
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No