This Small Business Innovation Research (SBIR) Phase I research project will demonstrate the feasibility of developing a tracheobronchial drug eluting stent (DES) by coating a biodegradable polymeric formulation of Paclitaxel (PTX) on a stent. The stent will provide immediate palliative therapy and… More

DESCRIPTION (provided by applicant): Airways can be obstructed by a variety of diseases resulting in breathing difficulties and compromised quality of life for the patients. Lung cancer is one of the major diseases causing airway obstruction. According to the American Cancer Society it is the… More

'The overall long-term objective of this proposal is to develop a loco-regional multi-functional theranostic delivery system (MTDS) to treat lung cancer in patients with focal disease, as an adjunct to systemic therapy. The proposed MTDS, releases a clinically proven, cocktail of cancer… More

Esophageal cancer is a deadly disease with limited treatment options. In addition to modest effects, toxic chemo-therapy drugs cripple patients with debilitating side-effects. This proposal utilizes an Esophageal Theranostic Delivery System (ETDS), to address this clinical need with a multi-modal… More