A new principle for fast and inexpensive evaluation of the size, depth and elastic moduli of smallbreast using mechanical sensor is developed. The long term objective of this project is to realize tclinical device for mass breast screening and early detection of cancer. Mathematical modeling… More

This proposal relates to the emerging technique of high precision ultrasonic velocimetry that has provided unique and remarkable insights on bimolecular interactions. Often much of the driving force for macromolecular associations comes from reorganization of bound water. The unique sensitivity of… More

A new principle for fast and inexpensive evaluation of the size, depth and elastic moduli of smallbreast using mechanical sensor is developed. The long term objective of this project is to realize tclinical device for mass breast screening and early detection of cancer. Mathematical modeling… More

Not Available Surveillance systems on-board unmanned space vehicles are required to have a wide field of regard and operate autonomously. Target detection, recognition, and tracking would be done using high-resolution imaging sensors cued by a lower resolution imaging sensor which is able to view… More

Not Available Vulnerability and survivability assessments require a ray-tracing tool capable of analyzing geometry created using Pro-Engineer. ThermoAnalytics proposes to extend their recently developed ray-tracer to meet this need. This modular ray-tracing tool currently calculates thermal view… More

DESCRIPTION (Provided by Applicant): The aim of this project is to develop a portable, low cost, fast and easy-to-use device for the quantitative assessment of bone quality that is suitable for mass screening and early identification of those at risk for osteoporosis. The device… More

DESCRIPTION (Provided by Applicant): The aim of this project is to develop a portable, low cost, fast and easy-to-use device for the quantitative assessment of bone quality that is suitable for mass screening and early identification of those at risk for osteoporosis. The device… More

DESCRIPTION (provided by applicant): We propose an internet-based dynamic imaging system for detecting and monitoring changes in structural properties of breast tissue that are indicative of breast cancer development. The method is based on the use of the proprietary… More

Description (provided by applicant): The goal of the project is to develop a portable cost-effective device for Mechanical Imaging (MI) of the prostate capable of evaluating mechanical properties and geometry of the prostate. The device comprises a transrectal probe, a compact electronic data… More

We propose a new Tactile Breast Imager (TBI) for early breast cancer detection intended for effective low-cost mass pre-screening. The device will build on developments made in the field of mechanical imaging (MI), a method that translates the tissue's elastic properties into a digital 3-D map of… More

The main goal of this project is contructing a lightweight, low-cost, real-time ultrasound system for bone assessment that could readily be used in long term space flights as well as in a variety of environments in general medical practice. The major goal of Phase I of this project was to construct… More

The main goal of this project is contructing a lightweight, low-cost, real-time ultrasound system for bone assessment that could readily be used in long term space flights as well as in a variety of environments in general medical practice. The major goal of Phase I of this project was to construct… More

DESCRIPTION (provided by applicant): Early detection of breast cancer remains one of the most significant challenges in health care. The tactile breast imager (TBI) is a promising solution that electronically captures the sense of touch to provide a quantitative, sensitive, and permanent record… More

Vibration based structural health monitoring using Time Reversal Acoustics (TRA)represents a new approach to in-situ nondestructive evaluation of airspace structures. The proposed noncontact technique is based on TRA focusing of high frequency vibrations in tested structures produced by single or… More

The objective of the proposed research is to develop new technologies based on principles of Time Reversal Acoustics (TRA) that will provide highly sensitive land mine detection. We suggest applying the Time Reversal Acousto-seismic method in combination with a nonlinear acousto-seismic mine… More

The objective of this proposal is to develop a Muscle Water Content (MWC) sensor, an ultrasonic device for assessment of body hydration status in soldiers with accuracy better than 2% during deployment and training. The MWC assessment is based on measurement of ultrasound velocity in muscle, which… More

Time Reversal Acoustic (TRA) structural health monitoring with an embedded sensor array represents a new approach to in-situ nondestructive evaluation of air-space systems. The suggested approach is based on a sufficient improvement of recently developed Electro-Mechanical Impedance method and will… More

DESCRIPTION (provided by applicant): Several million screening, diagnostic and therapeutic colonoscopies are performed each year in the U.S. hospitals and ambulatory surgery centers. The application of force to the colon and its anatomic attachments can be painful and excessive force can lead to… More

The objective of the proposed research is to develop new technologies and a prototype of the Time Reversed Acoustics (TRA) system of land mine detection. This system provides a high concentration of seismic wave energy at any desired point (e.g., on a land mine). It is the only system that is… More

DESCRIPTION (provided by applicant): The long-term goal of the project is to bring to the market a new tool for prostate cancer screening, the Prostate Mechanical Imager (PMI), which provides real time 3-D reconstruction of prostate capturing its geometrical and mechanical characteristics and aids… More

DESCRIPTION (provided by applicant): The goal of this project is to develop a Colonoscopy Force Monitor (CFM), a handheld attachment mounted on the colonoscope shaft which provides a physician with real-time feedback on the force and torque applied during colonoscopy. The CFM is designed to improve… More

DESCRIPTION (provided by applicant): Osteoporosis induced by aging as well as a side effect of certain drugs is a serious public health problem. The lack of adequate means for early detection of bone deterioration is the most critical issue in the problem of minimization of side effects of… More

The goal of the project is demonstration of the feasibility of Friction Stir Weld (FSW) assessment by novel Nonlinear Time Reversal Acoustic (TRA) method. Time reversal acoustic focusing provides the means to concentrate sound energy at any point in a material, inducing elastic nonlinear effects in… More

DESCRIPTION (provided by applicant): The main objective of this SBIR Phase I application is to demonstrate the feasibility of a novel technology for focusing ultrasound based on time-reversal acoustics (TRA) principle to improve the effectiveness of convec tion-enhanced delivery (CED) of drugs to… More

DESCRIPTION (provided by applicant): Pelvic organ prolapse is a highly prevalent condition affecting at least 50% of women in the US during their lifetimes. Some loss of utero-vaginal support occurs in most adult women, however, the true etiology of prolap se and differences seen among individuals… More

DESCRIPTION (provided by applicant): Each year, at least 10,000 critically sick babies in respiratory failure are intubated for ventilator support. For these babies, intubation bears major health risks such as airway emergencies, cardiopulmonary arrest, pn eumothoraces. Neonates, however young, can… More

DESCRIPTION (provided by applicant): Pelvic organ prolapse is a highly prevalent condition affecting at least 50% of women in the US during their lifetimes. Some loss of utero-vaginal support occurs in most adult women; however, the true etiology of prolapse and differences seen among individuals is… More

DESCRIPTION (provided by applicant): Colonoscopy is the preferred method to screen for colorectal cancer, a disease that afflicts 115,000 new patients a year. Several million screening, diagnostic and therapeutic colonoscopies are performed each year in U.S. hospitals and ambulatory surgery centers.… More

DESCRIPTION (provided by applicant): Dehydration is a frequent cause of morbidity and mortality in the elderly. Identifying at risk individuals and maintaining adequate fluid balance is an essential component of health care in the aging population. Currently, there is no effective tool available… More