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PORTABLE ULTRASONOMETER for OSTEOPOROSIS ASSESSMENT

Award Information

Agency:
Department of Health and Human Services
Branch:
N/A
Award ID:
55731
Program Year/Program:
2001 / SBIR
Agency Tracking Number:
2R44AG017400-02
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
ARTANN LABORATORIES, INC.
1459 LOWER FERRY RD TRENTON, NJ -
View profile »
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 2
Fiscal Year: 2001
Title: PORTABLE ULTRASONOMETER for OSTEOPOROSIS ASSESSMENT
Agency: HHS
Contract: N/A
Award Amount: $589,972.00
 

Abstract:

DESCRIPTION (Provided by Applicant): The aim of this project is to develop a portable, low cost, fast and easy-to-use device for the quantitative assessment of bone quality that is suitable for mass screening and early identification of those at risk for osteoporosis. The device will detect changes in the composition and micro-architectural properties of bone by measuring the ultrasound velocity, attenuation, spectral, and non-linear acoustic (NLA) parameters of bone at multiple sites along the skeleton with varied proportion of spongy and compact bone components. The manual scanning probe operating in surface pulse transmission mode will be used to obtain ultrasonic profiles in tested skeletal area. The diagnostic potential of NLA spectroscopy as a novel method for detecting the accumulation of microdamage in living bone will be evaluated. The feasibility of the proposed methods and devices has been proven in laboratory model studies and in pilot clinical trials. In Phase II of the project designed during Phase I will be developed into a fully functional and compact bone ultrasonometer with the manual scanning and NLA modes of operation, and clinically tested. Indexes of bone quality composed of several ultrasonic parameters will be developed for differential diagnostics of osteoporosis and mixed osteopenia. PROPOSED COMMERCIAL APPLICATIONS: Early evaluation and monitoring of osteoporosis is imperative for timely and effective treatment of the disease. According to the National Osteoporosis Foundation [1998 Report] the current economic burden associated with osteoporosis-related fractures is estimated at about $13.8 billion annually. There is an urgent need for advancement of the existing diagnostic techniques. The Proposed multi-site ultrasonometer offers higher diagnostic efficacy and specificity, lower cost, portability, and ease of operation. Developed device is ideally suited for the mass screening of osteoporosis and primary monitoring of population with high fracture risk.

Principal Investigator:

Armen Sarvazyan

Business Contact:


6093330710
ARMEN@PLUTO.NJCC.COM
Small Business Information at Submission:

ARTANN LABORATORIES, INC.
1753 LINVALE HARBOURTON RD LAMBERTVILLE, NJ 08530

EIN/Tax ID: 223503679
DUNS: N/A
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No