The objective of this research project is to produce a portable, miniaturized dialysis machine which is simple, safe, and symptom-free in operation. this dialysis machine should allow the average hemo-or peritoneal dialysis patient to perform dialysis by himself at home, unassisted. the machine will… More

Ash medical systems, inc. is developing two closely related devices that will improve home and hospital monitoring of glucose for diabetics. the common element of both devices is a fiber that is implanted subcutaneously. a negative pressure is applied to this fiber to withdraw tissue fluid. in the… More

Ash medical systems, inc. has developed a new sorbent-based,single-access hemodialysis machine that is safe, simple, and portable. the biologic-hd currently uses a plate dialyzer to actively pump blood while dialyzing the blood and a redy hisorb column to regenerate dialysate. previous research has… More

Effective hemodialysis requires a blood flow of 250 to 300 ml/minute. the usual method for obtaining this blood isto place two large needles into a fistula (arterialized vein) or a graft (ptfe conduit between artery and vein). both needles are removed at the end of each treatment. the objective of… More

The goal of this project is to adapt an existent single-access hemodialysis machine, the biologic-hd(tm), to perform nighttime peritoneal dialysis with high dialysate volumes. a disposable package on this machine will include a 30 liter bag which includes dry premeasured amounts of nac1, nahc03,… More

The goal of this project is to develop an extracorporeal device to revove large amounts of carbon dioxide (co2) from a relatively small flow rate of blood. this decarboxylator device could help support patients when respirator fail to remove sufficient co2 or be used in placeof respirators in… More

We have developed a dialysis system which is simple, safe, and portable. the biologic-hd system is a single access, sorbent based dialysis system with recently developed monitors to determine: total weight removal, blood flow rate, clotting of the dialyzer, and column saturation (a continually… More

Continuous subcutaneous insulin infusion has become an important method of treating insulin dependent diabetics because the better glucose control achievable by this method could potentially reduce the morbidity and mortality associated with the disease. current subcutaneous access is via a needle… More

Adverse drug interactions and toxicities are common in elderly patients. smartchart is a program that allows nurses and physicians to enter real-time clinical data into pc's from the bedside. the paper chart is generated througha microcomputer rather than by pen or dictation. during phase i,… More

"Early and effective hemodialysis can decrease mortality of trauma patients with acute renal failure, but current technology is not easily deployed in the field or during transit of patients. The "Redy" machine using the Sorb column was portable andutilized only 6 liters of water but did not make… More

Early and effective hemodialysis can decrease mortality of trauma patients with acute renal failure. Unfortunately, current technology is not easily deployed in the field or during transport of patients. The Sorbent Hemodialysis (SHD) System now beingdeveloped using technology from Ash Medical… More

DESCRIPTION (provided by applicant): Currently about 25% of patients on hemodialysis therapy for End Stage Renal Disease (ESRD) receives dialysis through tunneled central venous catheters for dialysis (CVCD). The standard anticoagulant lock for these catheters is heparin, which has no antibacterial… More

Not avaiable.