The diagnosis of pancreatitis would be facilitated by an immunoassay with increased specificity and sensitivity over the existing assays available to the clinician. the initialobjective of this proposal is to develop such an assay for one of the human pancreatic enzymes, cationic trypsin, which if… More

This proposal involves the development of a simple assay formeasuring functional (1)-proteinase inhibitor levels in human tissues. the procedure utilizes the fact that incubation of excess porcine pancreatic elastase with either plasma or serum samples will result in complex formation with… More

Caps of cell culture flasks used in conjunction with bicarbonate buffer systems must be left partially open to allow for carbon dioxide exchange. the presence of airbornecontaminants or leakage of media into the threads of the capthreatens to contaminate the culture. conversely, tightening the cap… More

Commercial catfish production is significantly impaired by infectious diseases, a major cause of economic losses to the catfish producer. one of the most detrimental of these infectious diseases is enteric septicemia of catfish (esc) caused by edwardsiella ictaluri. in 1987, approximately $4 million… More

Alzheimer's disease (ad), a leading health problem for this country, affects 5 to l0 percent of those over 65. by the year 2000, this aging population will double. a test permitting a definitive and early diagnosis of ad is greatly needed. we seek to develop such a diagnostic test using mabs it has… More