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POLYMERIC MEMBRANE APPLICATIONS TO IMPROVE CELL CULTURE

Award Information

Agency:
Department of Health and Human Services
Branch:
N/A
Award ID:
11246
Program Year/Program:
1989 / SBIR
Agency Tracking Number:
11246
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
Athens Research And Technology
P O Box 5494 Athens, GA 30604
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Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No
 
Phase 1
Fiscal Year: 1989
Title: POLYMERIC MEMBRANE APPLICATIONS TO IMPROVE CELL CULTURE
Agency: HHS
Contract: N/A
Award Amount: $50,000.00
 

Abstract:

CAPS OF CELL CULTURE FLASKS USED IN CONJUNCTION WITH BICARBONATE BUFFER SYSTEMS MUST BE LEFT PARTIALLY OPEN TO ALLOW FOR CARBON DIOXIDE EXCHANGE. THE PRESENCE OF AIRBORNECONTAMINANTS OR LEAKAGE OF MEDIA INTO THE THREADS OF THE CAPTHREATENS TO CONTAMINATE THE CULTURE. CONVERSELY, TIGHTENING THE CAP TOO MUCH LEADS TO THE LOSS OF SOME CULTURES BECAUSE OF IMPROPER GAS EXCHANGE. CELLGRO RESEARCH (CGR) PLANS TO DEVELOP A MEMBRANE THAT WILLALLOW ADEQUATE GAS EXCHANGE YET BLOCK THE PASSAGE OF MICROORGANISMS. THIS MEMBRANE WILL BE A NONPOROUS POLYMER PERMEABLE TO SMALL-MOLECULAR-WEIGHT GASES BUT IMPERMEABLE TO ANY SIZE BACTERIA OR VIRUS. CGR WILL INCORPORATE THIS MEMBRANE INTO THE CAPS OF CELL CULTURE FLASKS. TIGHTENING THESE MEMBRANE CAPS ON THE FLASKS WILL SOLVE CONTAMINATION AND GAS MAINTENANCE PROBLEMS. USING THESE MEMBRANES MAY ALSO ABOLISH THE NEED TO ADD ANTIBIOTICS TO CULTURE MEDIA. AS A RESULT, CELLS TO BE USED FOR HUMAN THERAPY MAY BE GROWNIN AN ANTIBIOTIC-FREE MEDIA, OVERCOMING THE PROBLEM OF POTENTIAL PATIENT REACTION TO THOSE ANTIBIOTICS.

Principal Investigator:


0

Business Contact:

Small Business Information at Submission:

Athens Research And Tech Inc
Box 5494 Athens, GA 30604

EIN/Tax ID:
DUNS: N/A
Number of Employees: N/A
Woman-Owned: No
Minority-Owned: No
HUBZone-Owned: No