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Mild Hypothermia Catheter for Reperfusion Injury

Company: 3DT HOLDINGS, LLC Agency/Program/Year/Phase: HHS / SBIR / 2014 / 1
Abstract: ABSTRACT ST segment myocardial infarction (STEMI) is a serious acute coronary condition that affects 500,000 Americans each year and results in significant U.S. healthcare costs ( 31B/year for acute MI treatment). STEMI mortality directly relates to the extent of the total myocardial injury and even… more

A Practical Tool for Managing the Complexity of Biologics Process Manufacturing

Company: ADVANCED PROCESS COMBINATORICS, INC. Agency/Program/Year/Phase: HHS / SBIR / 2014 / 2
Abstract: DESCRIPTION (provided by applicant): Biologics manufacturing based on cell culture techniques represents a tremendous advance in the pharmaceutical industry. The use of biological rather than chemical processes result in unique therapeutics with greater profitability, a knowledge-based barrier to… more

Confocal and Autofluorescence Imaging of Macular Degeneration using a Low Cost Di

Company: AEON IMAGING, LLC Agency/Program/Year/Phase: HHS / SBIR / 2014 / 1
Abstract: Project Summary / Abstract - PA-13-088 The overall goal of the proposed SBIR Phase I research is to build and begin initial evaluation of a low cost, portable retinal camera used to detect age-related macular degeneration and other retinal degenerations.Age-related macular degeneration remains the… more

Cost-Effective OCT Detection of Vision-Threatening Macular Edema

Company: AEON IMAGING, LLC Agency/Program/Year/Phase: HHS / SBIR / 2014 / 1
Abstract: DESCRIPTION (provided by applicant): I The overall goal of the proposed SBIR program is to implement and evaluate a low cost, portable retinal camera, the Digital Light Ophthalmoscope (DLO), with retinal thickness measurement functionality provided by optical coherence tomography (OCT). The… more

High Power Density, High Efficiency Advanced Generator for DEW Systems

Company: Candent Technologies Incorporated Agency/Program/Year/Phase: DOD / SBIR / 2014 / 1
Abstract: Solid state RF and millimeter wave weapons systems require substantial power to operate. Pure solid state systems have limited energy density and require charging over the typical use cycle. The directed energy system must be compact enough to mount on a vehicle such as a HMMWV, a small trailer or a… more

Efficient Light Weight Propulsion for Small Unmanned Surface Vehicle

Company: Candent Technologies Incorporated Agency/Program/Year/Phase: DOD / SBIR / 2014 / 2
Abstract: The Phase I of this SBIR completed the design, fabrication, and demonstration of a prototype heavy fuel engine for the Class X USV, and also completed the preliminary design of the waterjet propulsor as well as the preliminary design of the systems and the integration with the hull. Phase II of the… more

Combined Extinction/Flourescence Absorption Diagnostics for Pharmaceutical Sprays

Company: EN'URGA INC. Agency/Program/Year/Phase: DOC / SBIR / 2014 / 1
Abstract: This Phase I project will evaluate the feasibility of a pharmaceutical spray quality audit system. The spray quality audit system will estimate the mass distribution of active ingredients and droplet sizes in pharmaceutical sprays using combined fluorescence absorption and light extinction… more

A Low Cost Sensor for Mid-Chord Offset Measurements

Company: EN'URGA INC. Agency/Program/Year/Phase: DOT / SBIR / 2014 / 1
Abstract: This Phase I SBIR project will evaluate the feasibility of utilizing low cost and high accuracy local position sensors and transmitters to autonomously estimate Mid-chord offset in rails. The two innovative parts of the proposed system are (1) a set of miniature and highly accurate local position… more

A Low-Cost Quantitative Anemia Detection Method for Livestock

Company: EN'URGA INC. Agency/Program/Year/Phase: USDA / SBIR / 2014 / 1
Abstract: Gastrointestinal parasites are the most important pathogens of sheep and goats worldwide. Anemia is the primary sign of internal parasite infection, and many sheep die of blood loss anemia secondary to abomasal parasites. Anemia results in pale mucous membranes and conjunctiva in animals and humans.… more

A Particulate Mass Flux Sensor for the Food Process Industry

Company: EN'URGA INC. Agency/Program/Year/Phase: USDA / SBIR / 2014 / 2
Abstract: Currently, the vast majority of food products are made using batch processing. However, in most manufacturing operations, continuous processing methods provide for higher efficiency as well as greater quality in the finished product. This paradigm is not yet present in the food industry due to one… more

Surface Treatments for Stainless Steel Actuators

Company: IBC Materials & Technologies Agency/Program/Year/Phase: DOD / SBIR / 2014 / 1
Abstract: ABSTRACT: Stainless steel ballscrew components, such as those found in landing gear and flap actuators on the C-130 aircraft, experience wear and subsequent failure due to corrosion, contamination and foreign object damage (FOD). High"dither"conditions, where the actuator undergoes a… more

Plasma Electrolytic Diffusion Treatments for Reduced Electrochemical Current Density in Aircraft Structural Fasteners

Company: IBC Materials & Technologies Agency/Program/Year/Phase: DOD / STTR / 2014 / 1
Abstract: Modern aircraft make extensive use of fasteners made of steel, titanium, nickel and other alloys mated with aluminum and composite airframe materials. This coupling of dissimilar materials yields galvanic corrosion issues, which degrades mechanical integrity, is costly to inspect, and poses a safety… more

Method for Evaluating Candidates for Additive Manufacturing (AM) Processes

Company: Imaginestics, LLC Agency/Program/Year/Phase: DOD / SBIR / 2014 / 1
Abstract: ABSTRACT: A challenge which continues to present a barrier to the utilization of AM and wide spread adoption is knowing when to use the technology. This is particularly problematic in aerospace and in MRO operations because the technology is still emerging, and knowledgeable, experienced… more

STTR Phase I: Digital Immersive Gaming Infrastructure for Innovating Undergraduate STEM Courses via an Immersive Game-Based Approach to Teaching and Learning

Company: WisdomTools Enterprises Inc Agency/Program/Year/Phase: NSF / STTR / 2014 / 1
Abstract: This STTR Phase I project's broader/commercial impact is to produce a replicable education platform that can be applied to many types of higher education courses. The initial commercialization will focus on information systems/information technology courses because it is a content area taught… more

Air Cycle Toolsets for Aircraft Thermal Management System (TMS) Optimization

Company: PC Krause and Associates, Inc. Agency/Program/Year/Phase: DOD / SBIR / 2014 / 1
Abstract: ABSTRACT: Modern military aircraft are encountering major thermal obstacles as a result of significant increases in on-board heat generation combined with a reduced ability to transfer heat to the ambient environment. Adaptive power and thermal management systems (APTMS) are being studied in great… more

Dynamic Time and Frequency Domain Modeling of Aircraft Power System with Electrical Accumulator Units (EAU)

Company: PC Krause and Associates, Inc. Agency/Program/Year/Phase: DOD / SBIR / 2014 / 2
Abstract: The movement to more-electric architectures in airborne systems has drastically altered the dynamics of power flow in the EPS with the addition of numerous high-power electric loads and has increased the complexity of designing the electrical power system (EPS). Such high-power dynamic loads may… more

Intelligent Power Management Module for Autonomous Power Generator Operation

Company: PC Krause and Associates, Inc. Agency/Program/Year/Phase: DOD / SBIR / 2014 / 2
Abstract: The US Army and Marines rely significantly on fossil-fuel based tactical power generation to provide electrical energy to deployed troops in small camps and forward operation bases. These generators are sized to support the expected maximum power but are

Clinical Trial of the FAST Real-Time GFR System

Company: PHARMACOPHOTONICS, INC. Agency/Program/Year/Phase: HHS / SBIR / 2014 / 2
Abstract: DESCRIPTION (provided by applicant): PharmacoPhotonics (DBA FAST, Inc.) proposes Fast-Track research to determine GFR in its first human Pilot study. The long-term goal of this SBIR project is to test FAST's minimally invasive catheter based fluorescent device in humans and commercialize this… more

Quick Release Connector

Company: SkySight Technologies LLC Agency/Program/Year/Phase: DHS / SBIR / 2014 / 2
Abstract: The proposed SkySight Technologies Quick Release Connector will independently detect an unexpected mechanical load on the power distribution line. The compact and lightweight SkySight Quick Release Connector uses existing methods and hardware to integrate into the infrastructure, and no special… more

Downed Power Line Sensor

Company: SkySight Technologies LLC Agency/Program/Year/Phase: DHS / SBIR / 2014 / 1
Abstract: The proposed SkySight Technologies Downed Power Line Sensor will detect and alert the presence of a downed power line and its energized status through a sensor on the power line. In the event of a downed power line, an alert message is sent via wireless network to the utility provider regarding the… more

Finite Internal Temperature Slide for Use with Colloid Experiments

Company: TECHSHOT, INC. Agency/Program/Year/Phase: NASA / SBIR / 2014 / 1
Abstract: The Light Microscopy Module (LMM), developed and managed by NASA Glenn Research Center (GRC), is producing fascinating results. LMM will yield even more astonishing results with the addition of enhancing subsystems. Techshot is developing one such subsystem, the LMM-Dynamic Stage (LMM-DS), which… more

A Simple, Robust Lightweight Microscopy and Sample Processing System for Scientific and Commercial Research on ISS

Company: TECHSHOT, INC. Agency/Program/Year/Phase: NASA / SBIR / 2014 / 1
Abstract: A light-weight, user-friendly, algorithmically or remotely controlled microscope, not purchased from a microscope company, coupled to fluid sample processing and sample changing systems is proposed. It is an easy-access light microscope consisting of a novel illuminator-condenser with no moving… more

Electrical System for Rapidly Detecting Viable Bacteria in Blood Culture

Company: TECHSHOT, INC. Agency/Program/Year/Phase: HHS / SBIR / 2014 / 2
Abstract: DESCRIPTION (provided by applicant): Background: Each year in the US, there are over 18 Million Blood Cultures performed to determine the presence/absence of viable microorganisms in the blood of patients suspected of having Blood Steam Infection (BSI or Septicemia). Current technology for Blood… more

Modular Shading Structure for High Value Fruits and Vegetables

Company: Trellis Growing Systems Agency/Program/Year/Phase: USDA / SBIR / 2014 / 2
Abstract: Commercial farms growing high value fruits and vegetables use shade structures to create protected environments. These growers benefit from bigger yields, better quality produce, fewer pests, timed crop growth, and resource conservation. Unfortunately, shade structure use is limited for many small… more

A Universal Device for Performing Cricothyrotomies

Company: Wolf Technical Services, Inc. Agency/Program/Year/Phase: DOD / SBIR / 2014 / 1
Abstract: The purpose of this multi-phase program is to develop an innovative all-in-one surgical instrument for performing cricothyrotomies and managing airway trauma on the battlefield, with improvements aimed at ultimately reducing mortality rates associated with these procedures. The Wolf QuickCric is… more