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Improved Turbo/Superchargers for UAS/UGS Application

Company: Brayton Energy Agency/Program/Year/Phase: DOD / SBIR / 2014 / 1
Abstract: Brayton Energy is a developer of turbomachinery systems, specializing in gas turbines, turbojets, turbochargers, and turbo-compounding equipment. In the proposed program, Brayton will design and bench-test the critical elements of novel single-shaft turbocharger with integral motor/alternator… more

Flexible All-metal Pipes and Pipe Couplings For High-Temperature Fluid Transport

Company: Brayton Energy Agency/Program/Year/Phase: DOE / SBIR / 2014 / 1
Abstract: Molten salt heat transfer fluid a desirable upgrade to solar plant designs because of its superior temperature, thermal, and pumping properties compared to steam or heat transfer oil. It is non- hazardous to the environment, not flammable, and easy to transport and clean up. It is advantageous for… more

Mobile Vibratory Impactor for AI-Based Detection of Void under AM-2 Matting

Company: AAC International Agency/Program/Year/Phase: DOD / SBIR / 2014 / 1
Abstract: A mobile vibratory roller impactor system is proposed, using AI-based pattern recognition for identification of voids through analyzing the tapping force on the AM-2 mat exerted by the roller impactor. The Phase I project will conduct feasibility demonstration of the proposed technology. The basic… more

Operational SAR Forest Structure and Disturbance Metrics

Company: APPLIED GEOSOLUTIONS, LLC Agency/Program/Year/Phase: USDA / SBIR / 2014 / 1
Abstract: The goal of the SBIR is to "Operationalize multiscale Synthetic Aperture Radar (SAR) forest structure and disturbance metrics". The objectives are to develop 1.) operational forest structure and disturbance metrics derived from Synthetic Aperture Radar and 2.) mapping information services… more

CyanoMap: Mapping inland lake quality and Amyotrophic lateral sclerosis risk fact

Company: APPLIED GEOSOLUTIONS, LLC Agency/Program/Year/Phase: HHS / SBIR / 2014 / 2
Abstract: DESCRIPTION (provided by applicant): Amyotrophic lateral sclerosis (ALS) is a progressive, fatal neurodegenerative disease with a lifetime risk of 1 in 400 for a young adult (Armon 2007). The average life expectancy of a person with ALS is two to five years from time of diagnosis with 5,600 new… more

TECHNICAL PROPOSAL FOR THE SHIPBOARD LIGHTING SYSTEM (AVIATION LIGHTING SYSTEM-CONTROL PANEL SET (ALS-CPS)) SBIR N04-081 PHASE II

Company: C3I, Inc. Agency/Program/Year/Phase: DOD / SBIR / 2014 / 2
Abstract: This Proposal identifies the tasks to be performed by C3I for the partial completion of the Aviation Lighting System Control Panel Set (ALS-CPS) technology developments of SBIR Topic N04-081. The Advanced Lighting System Control Panel Set (ALS-CPS) components include a 12"Control Panel… more

Advanced Titanium Purchase Cable for Lighter Weight and Longer Life

Company: Erigo Technologies LLC Agency/Program/Year/Phase: DOD / SBIR / 2014 / 1
Abstract: Enabling aircraft to land on an aircraft carrier requires an arresting gear system that can quickly pull the aircraft to a halt. One of main components of the current arresting gear system are the purchase cables that connect to a series of hydraulic and pneumatic engines that provide the braking… more

Destroying the HIV-1 provirus by utilizing components of the CRISPR/Cas system

Company: CELDARA MEDICAL, LLC Agency/Program/Year/Phase: HHS / SBIR / 2014 / 1
Abstract: DESCRIPTION (provided by applicant): The goal of this project is to develop a plasmid-based therapy that will destroy the integrated HIV-1 DNA (HIV- 1 provirus) in infected cells. Current HIV-1 anti-retroviral therapy (ARV) consists of a cocktail of drugsthat blocks viral binding and replication,… more

Dampening CAR therapy-induced cytokine storm with anti-GM-CSF antibodies

Company: CELDARA MEDICAL, LLC Agency/Program/Year/Phase: HHS / SBIR / 2014 / 1
Abstract: DESCRIPTION (provided by applicant): The long-term aim of this project is to reduce or eliminate the serious adverse events associated with cellular immunotherapy used to treat cancer. The current impressive efficacy of chimeric antigen receptor (CAR) T cell therapies is often accompanied by a… more

Therapy of transplantation-induced oxidative injury using polymeric antioxidants

Company: CELDARA MEDICAL, LLC Agency/Program/Year/Phase: HHS / SBIR / 2014 / 1
Abstract: DESCRIPTION (provided by applicant): Ischemia-reperfusion (I/R) injury during renal transplantation surgery is responsible for oxidative stresses which result in immune activation and graft rejection. We are developing an antioxidative therapy that we havealready shown to be highly efficacious in… more

PHASE I, SBIR CONTRACT, N43TR-14-001, ?MUTIPLEXED BIOMARKER ASSAY FOR CLASSIFICATION OF PATIENTS?.

Company: CELDARA MEDICAL, LLC Agency/Program/Year/Phase: HHS / SBIR / 2014 / 1
Abstract: Not Available

Gene Expression Signatures to Predict Treatment Response in Systemic Sclerosis

Company: CELDARA MEDICAL, LLC Agency/Program/Year/Phase: HHS / SBIR / 2014 / 2
Abstract: DESCRIPTION (provided by applicant): Today, systemic sclerosis (SSc) clinical trials generally include all subsets; some may benefit, others do not, confounding measures of efficacy. Because each expression subset has a different underlying deregulated molecular pathway, no single drug is expected… more

Thermal Isolation of Nozzle Exit Cone Insulators

Company: Mentis Sciences, Inc. Agency/Program/Year/Phase: DOD / SBIR / 2014 / 2
Abstract: Mentis and SDC are developing materials suitable for operating in extreme environments, such as those experienced by exit nozzles in Throttleable Divert and Attitude Control Systems (TDCAS), or as thermal protection in ballistic missiles and payload delivery systems. A material characterization… more

Rain Erosion Modeling for Hypersonic Thermal Protection System (TPS) and Structures

Company: Mentis Sciences, Inc. Agency/Program/Year/Phase: DOD / SBIR / 2014 / 2
Abstract: Mentis Sciences (Mentis) is providing Low Rate Initial Production (LRIP) line to produce a Radome Assembly (RA). Mentis"focus is to assure all elements of the production process approaches a Manufacturing Readiness Level (MRL) 8. This effort requires developing processes and Design of… more

Compact Advanced Hypoxia Training System (CAHTS)

Company: Creare, Inc. Agency/Program/Year/Phase: DOD / SBIR / 2014 / 1
Abstract: Hypoxia is a dangerous condition for naval aviators that impacts critical thinking, resulting in a lack of awareness that prevents aircrew from taking appropriate corrective actions. Practical hypoxia training allows pilots to experience the effects of hypoxia so that the symptoms are more readily… more

A High-Precision, High-Resolution Turbine Blade Inspection System

Company: Creare, Inc. Agency/Program/Year/Phase: DOD / SBIR / 2014 / 1
Abstract: Modern jet engine turbine blades are single-crystal superalloy structures with excellent resistance to high-temperature creep, allowing tight tolerances to be maintained over the blade"s life. However, turbine blades have complicated features that can promote the growth of discrete crystal… more

Development of an Advanced Bearing for Extreme Service Environments

Company: Creare, Inc. Agency/Program/Year/Phase: DOD / SBIR / 2014 / 1
Abstract: Aircraft carriers are the backbone of the U.S. Navy"s fleet, which operates around the globe, with the sole purpose of launching and recovering aircraft to support U.S. military and peacekeeping interests. The ability to quickly and safely launch aircraft can become a key limitation for an… more

A CubeSat-Compatible Neutral Wind Sensor

Company: Creare, Inc. Agency/Program/Year/Phase: DOD / SBIR / 2014 / 2
Abstract: ABSTRACT: CubeSats provide a new, low-cost platform for space weather missions. They enable new mission paradigms, such as the ability to perform multiple measurements of the same physical phenomena globally from several satellites, in contrast to high-accuracy measurements of multiple phenomena… more

Modular Anatomical Test Target for Non-Lethal Weapons

Company: Creare, Inc. Agency/Program/Year/Phase: DOD / SBIR / 2014 / 1
Abstract: Non-lethal weapons (NLWs) are increasingly being used in conflict situations where lethal force is undesirable. As new non-lethal systems are developed, careful evaluation is required to confirm both effectiveness and non-lethality over various payload and range conditions. Computer simulations can… more

A Low Cost Electromagnetic Induction Ground Fault Detector

Company: Creare, Inc. Agency/Program/Year/Phase: DOD / SBIR / 2014 / 2
Abstract: Machinery Control System (MCS) cabling faults can be difficult to identify and locate since as many as 3,000 to 5,000 I/O points are used and multiple junctions exist in each cable. A single MCS fault can require as many as four maintainers and a full day of troubleshooting to isolate and resolve,… more

Low-Cost Compact Microchannel Heat Exchanger With Uniform Flow Distribution

Company: Creare, Inc. Agency/Program/Year/Phase: DOD / SBIR / 2014 / 1
Abstract: Increasing use of high power density electronics systems in military vehicles and buildings will significantly increase thermal loads of their Environmental Control Systems (ECS). Advanced thermal management technology is needed for these ECSs. We propose to develop a highly effective, low-cost heat… more

Passive Optical Combustion Sensors for Scramjet Engine Control

Company: Creare, Inc. Agency/Program/Year/Phase: DOD / SBIR / 2014 / 2
Abstract: ABSTRACT: Dual-mode scramjet engines must operate over a wide range of flight Mach numbers. Closed-loop engine control is necessary to maintain thrust and flame stability while preventing unstart over the large flight envelope. High-frequency sensors and actuators will be a key component of… more

Compact, Reliable Air Dryer to Prevent Icing in Air Cycle Machine

Company: Creare, Inc. Agency/Program/Year/Phase: DOD / SBIR / 2014 / 1
Abstract: ABSTRACT: Reducing the temperature of air exiting an Air Cycle Machine (ACM) is an effective way to increase the cooling capacity of Environmental Control Systems. However, this requires a colder turbine inlet air, which can increase the risk of icing in the upstream condenser. To mitigate this… more

A Novel Smart Installation System for Airframe Production

Company: Creare, Inc. Agency/Program/Year/Phase: DOD / SBIR / 2014 / 1
Abstract: ABSTRACT: The installation of EDDIE BOLT fasteners in aerospace assembly is a time consuming process requiring multiple inspections of 100% of the installation of thousands of fasteners per aircraft. After installation, the fastener is inspected multiple times to ensure proper installation,… more

High-Signal, Unseeded Molecular Tagging Velocimetry in Hypersonic Nitrogen Flows

Company: Creare, Inc. Agency/Program/Year/Phase: DOD / SBIR / 2014 / 1
Abstract: ABSTRACT: Velocimetry measurements in large-scale hypersonic test facilities are challenging because intrusive physical probes produce shock waves that disturb the flow field and conventional seeded methods require injection of particles or gas that are unacceptable. Seedless velocimetry… more