Dynamic Narrative Generation Software To Improve Social And Behavioral School Readiness Skills Needed For The Successful Transition To Grade School
Company: 3-C Institute for Social Development Agency/Program/Year/Phase: ED / SBIR / 2013 / 1Abstract: The project team is developing a prototype of a web-based intervention for pre-kindergarten and kindergarten students to prepare for the transition to grade school. The product will support students as they create stories using a step-by-step scripted interactive process. The stories will focus on… more
Hall Of Heroes: An Interactive Social Tutoring System To Improve And Measure Social Goals For Students In Preparation For Transition To Middle School
Company: 3-C Institute for Social Development Agency/Program/Year/Phase: ED / SBIR / 2013 / 2Abstract: Hall of Heroes will be a web-based game for fifth graders to engage with pedagogical agents (animated life-like characters) to solve tailored social problem solving tasks and build social skills to use in challenging situations. Instructional content will focus on six core Social Skill Units… more
Dynamic E-Learning to Improve Postsecondary Transition Outcomes for Secondary Students with High Functioning Autism
Company: 3-C Institute for Social Development Agency/Program/Year/Phase: ED / SBIR / 2013 / 1Abstract: This project team will develop a web-based product to engage 11th and 12th grade high school students with HF-ASD in a self-paced online interactive course to learn about the transition to college, learn specific resilience strategies for coping with the transition to college, and to practice… more
SBIR Phase I: Feasibility of The Use of a Debris Cartridge in an External Drainage Device
Company: CAMRAS VISION, INC. Agency/Program/Year/Phase: NSF / SBIR / 2013 / 1Abstract: This Small Business Innovation Research Phase I project will demonstrate the feasibility of the use of a debris cartridge in an implant to prevent obstruction in debris-releasing glaucomas, such as uveitic, pigment-dispersion, and pseudoexfoliation glaucomas. Glaucoma is a group of chronic eye… more
SBIR PhaseI: High Velocity Impact Bonding of Dissimilar Metals by Energy Released in Chemical Production of Hydrogen
Company: Advanced Hydrogen Technologies Corporation Agency/Program/Year/Phase: NSF / SBIR / 2013 / 1Abstract: This Small Business Innovation Research (SBIR) Phase I project seeks to advance manufacturing processes in the dissimilar metal/impact welding industries via an aluminum/water reaction that chemically produces hydrogen energy. Ideally, the energy in the form of about 100 kpsi-200 kpsi, could be the… more
Keratin biomaterial-based fluid for trauma resuscitation
Company: KeraNetics, LLC Agency/Program/Year/Phase: HHS / SBIR / 2012 / 2Abstract: DESCRIPTION (provided by applicant): Although numerous advances have been made in the treatment of severe hemorrhage, current blood plasma substitutes do not address new insights in resuscitation medicine. Research in fluid technologies and vascular response following significant pre-hospital… more
Development of Biomaterial Scaffolds for Use in Regenerating Muscle Tissue
Company: KeraNetics, LLC Agency/Program/Year/Phase: DOD / SBIR / 2012 / 1Abstract: Injuries to soft tissues in extremities represent a high percentage of battlefield wounds in recent conflicts. Therapies for restoring function to injured muscle are needed for Wounded Warriors suffering from debilitating and sometimes disfiguring musculoskeletal injuries. Regenerative medicine… more
Spatiotemporally Controlled Keratin Biomaterial Delivery System for Functional Tissue Regeneration Phase II
Company: KeraNetics, LLC Agency/Program/Year/Phase: DOD / SBIR / 2012 / 2Abstract: Skeletal muscle injury is a significant challenge to warfighters due to the severity of the injuries often caused by Improvised Explosive Devices. Currently, there are few viable clinical treatment options for these types of injuries. Keratin hydrogels offer a solution to these challenges as… more
Flowable keratin biomaterials for improving infection control and wound healing.
Company: KeraNetics, LLC Agency/Program/Year/Phase: DOD / SBIR / 2012 / 1Abstract: The improvement of body armor, equipment, and decreases in patient transport times have dramatically improved survival of combat injuries. However, data suggests that future conflicts will require more aggressive wound management at the point of injury to deal with more complex wounds particularly… more
IGF::OT::IGF OTHER FUNCTIONS DEVELOPMENT OF A UNI-DIRECTIONAL BRACHYTHERAPY DEVICE FOR THE TREATMENT OF NON-SMALL-CELL LUNG CANCER
Company: CIVATECH ONCOLOGY, INC. Agency/Program/Year/Phase: HHS / SBIR / 2012 / 2Abstract: According to the American Cancer Society 220,000 men and women in the U.S. develop lung and bronchial cancer every year and 147,000 die of the disease. Of lung cancer patients, 85% present with non-small-cell lung cancer and 16.7% of these will present with localized disease. Note that lung cancer… more
Robust and Sustainable Utilization of Biofuel Co-Products to increase Biorefinery Diversification
Company: Piedmont Biofuels Industrial Agency/Program/Year/Phase: USDA / SBIR / 2012 / 1Abstract: Reducing foreign dependence on petroleum-based materials is a key to enhancing the US agricultural economy in the long-term. In recent years with the rising costs of petrochemical prices, there has been an increasing interest in renewable sourced specialty chemicals. Presently, less than 4 percent… more
Social Tutor for Supporting the Transition from Elementary to Middle School
Company: 3-C Institute for Social Development Agency/Program/Year/Phase: ED / SBIR / 2012 / 1Abstract: A growing body of research underscores the need to prepare students socially—as well as academically—to ensure successful transition to middle school and foster subsequent academic success. This project team is developing a prototype of a series of web-based interactive games to help students… more
Web-Based Dissemination Tool for Community Mental Health (WDT-C)
Company: 3-C INSTITUTE FOR SOCIAL DEVELOPMENT Agency/Program/Year/Phase: HHS / SBIR / 2012 / 2Abstract: DESCRIPTION (provided by applicant): Over the past several decades, a large number of mental health (MH) practices and interventions have been rigorously tested through randomized control trials and shown efficacious. However, despite availability, evidence-based interventions (EBIs) are rarely… more
Research Implementation and Management System
Company: 3-C INSTITUTE FOR SOCIAL DEVELOPMENT Agency/Program/Year/Phase: HHS / SBIR / 2012 / 2Abstract: DESCRIPTION (provided by applicant): Clinical science and its translation into preventive and clinical patient care are the primary means by which the nation's health care goals are fulfilled. NIH's broad mission to improve health outcomes for all people can only be achieved if scientific… more
Parent Education and Resources for Self-Injurious Youth
Company: 3-C INSTITUTE FOR SOCIAL DEVELOPMENT Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1Abstract: DESCRIPTION (provided by applicant): Non-suicidal self-injury (NSSI) is an increasingly common self-harming behavior among adolescents and young adults, with current estimates of NSSI in youth ranging from 12-37%. Although NSSI is associated with other mental health problems (e.g., depression,… more
See It, Be It: Interactive Technology to Increase School Engagement and Prevent D
Company: 3-C INSTITUTE FOR SOCIAL DEVELOPMENT Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1Abstract: DESCRIPTION (provided by applicant): Although high school success and completion are among the most important determinants of future life outcomes, over half a million adolescents in the United States drop out of school each year. School dropout has negative individual (e.g., increased likelihood of… more
Individualized Training and Practice in Career Navigation Skills
Company: 3-C INSTITUTE FOR SOCIAL DEVELOPMENT Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1Abstract: DESCRIPTION (provided by applicant): As emphasized by the NIH Roadmap and NCRR's Strategic Priorities, NIH's broad mission to improve health outcomes for all persons depends on the ability to train and retain future generations of clinical and translational researchers who can quickly and… more
Lab-on-a-Chip for Multiplexed Newborn Screening of Lysosomal Storage Disorders
Company: Advanced Liquid Logic, Inc. Agency/Program/Year/Phase: HHS / SBIR / 2012 / 2Abstract: DESCRIPTION (provided by applicant): Newborn screening is currently performed by collecting dried bloodspots from infants and then sending them to a lab for analysis. It is primarily performed to detect disorders which lead to severe physical and mental disabilities. There is an increasing necessity… more
Multiplex platform for point of care newborn screening of hyperbilirubinemia
Company: Advanced Liquid Logic, Inc. Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1Abstract: DESCRIPTION (provided by applicant): Jaundice is the most common condition that requires urgent medical attention in some newborns and is the result of elevation in circulating unconjugated bilirubin. The unbound unconjugated bilirubin can be specificallyneurotoxic and, if untreated, is associated… more
Peptide conjugation for Co-Delivery of Growth Factors and Stem Cells
Company: AFFINERGY ,INC Agency/Program/Year/Phase: HHS / SBIR / 2012 / 2Abstract: DESCRIPTION (provided by applicant): Autologous stem cells and growth factors provide valuable therapies for a variety of indications. When stem cells and growth factors are co-delivered, they produce a greater therapeutic effect than delivery of either stem cells or growth factors alone. However,… more
Development of an adipose-derived stem cell isolation matrix
Company: AFFINERGY ,INC Agency/Program/Year/Phase: HHS / SBIR / 2012 / 2Abstract: DESCRIPTION (provided by applicant): Approximately 500,000 bone-grafting procedures are performed each year in the United States. Autologous iliac crest bone graft continues to be the gold standard, because it provides essential elements for bone formation: progenitor cells, an osteoconductive… more
Bioactive Peptide Coatings for Synthetic Bone Grafts
Company: AFFINERGY ,INC Agency/Program/Year/Phase: HHS / SBIR / 2012 / 2Abstract: DESCRIPTION (provided by applicant): Back pain is one of the leading reasons for physician visits in the United States and in many cases requires surgical intervention. In the United States, there are over 500,000 spinal fusion surgeries every year, and the frequency of these surgeries is projected… more
Delivery of Adipose Derived Stem Cells for Healing Surgical Hernia Repairs
Company: AFFINERGY ,INC Agency/Program/Year/Phase: HHS / SBIR / 2012 / 2Abstract: DESCRIPTION (provided by applicant): Over 700,000 surgical hernia repairs are performed each year in the United States and despite recent advances, a significant rate of recurrence persists. Of these surgeries, 100,000 are for incisional or visceral herniarepairs, which cost 1.7B annually and have a… more
Novel coatings on titanium implants for the delivery of stem cells
Company: AFFINERGY ,INC Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1Abstract: DESCRIPTION (provided by applicant): Calvarial reconstruction continues to present challenges for surgeons. Although the gold standard for restoration of the skull is autologous bone, particularly from the removed flap, substitutes are often necessary dueto the flap becoming infected or infiltrated… more
Peptide-coated skin substitutes for the treatment of burn injuries and wounds
Company: AFFINERGY ,INC Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1Abstract: DESCRIPTION (provided by applicant): Burn injuries and chronic wounds present a significant burden to patients and the US healthcare system. Each year in the US, there are 450,000 burns that require medical treatment and 45,000 burns that require hospitalization. One of the most common causes of… more