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Integrated GaN T/R MMIC for AESA Radar

Company: Vadum Agency/Program/Year/Phase: DOD / SBIR / 2014 / 1
Abstract: Vadum proposes to develop an innovative, highly integrated, power-conserving GaN T/R MMIC for radar applications. We will leverage expertise in high efficiency, high power Gallium Nitride Power Amplifiers, low loss GaN RF switches, Low Noise Amplifiers, GaN Monolithic Microwave Integrated Circuits,… more

KeraStat(TM) Burn Gel and Halofuginone to Prevent Scar Contracture after Burn Injuries

Company: KeraNetics, LLC Agency/Program/Year/Phase: DOD / SBIR / 2013 / 1
Abstract: This Phase I project is relevant to the ultimate goals of this program announcement given the prevalence of the IED which often creates complex burn wounds on the face and skin that often form hypertrophic scars that often contract over time. Burn wound healing is a complex process that includes… more

Flowable keratin biomaterials for improving infection control and wound healing, Phase 2.

Company: KeraNetics, LLC Agency/Program/Year/Phase: DOD / SBIR / 2013 / 2
Abstract: Improvements in body armor, availability of equipment, and decreased patient transport times have dramatically improved Soldiers"survival of combat injuries. Data suggests that future conflicts will require more aggressive wound management at the point of injury to deal with more complex… more

Novel Manufacturing Processes for Tissue Engineered Vascular Grafts

Company: HUMACYTE, INC. Agency/Program/Year/Phase: HHS / SBIR / 2013 / 2
Abstract: DESCRIPTION (provided by applicant): This Phase IIB SBIR application is responsive to NHLBI RFA HL-13-016, NHLBI SBIR Phase IIB Bridge Awards to Accelerate the Commercialization of Technologies for Heart, Lung, Blood and Sleep Disorders and Diseases (R44) . This RFA solicits work on basic,… more

SBIR Phase II Topic 272: Low-Cost Microfluidic System for Detection of CTCs; Peri

Company: BIOFLUIDICA MICROTECHNOLOGIES, LLC Agency/Program/Year/Phase: HHS / SBIR / 2013 / 2
Abstract: Not Available

Dynamic Narrative Generation Software To Improve Social And Behavioral School Readiness Skills Needed For The Successful Transition To Grade School

Company: 3-C Institute for Social Development Agency/Program/Year/Phase: ED / SBIR / 2013 / 1
Abstract: The project team is developing a prototype of a web-based intervention for pre-kindergarten and kindergarten students to prepare for the transition to grade school. The product will support students as they create stories using a step-by-step scripted interactive process. The stories will focus on… more

Hall Of Heroes: An Interactive Social Tutoring System To Improve And Measure Social Goals For Students In Preparation For Transition To Middle School

Company: 3-C Institute for Social Development Agency/Program/Year/Phase: ED / SBIR / 2013 / 2
Abstract: Hall of Heroes will be a web-based game for fifth graders to engage with pedagogical agents (animated life-like characters) to solve tailored social problem solving tasks and build social skills to use in challenging situations. Instructional content will focus on six core Social Skill Units… more

Dynamic E-Learning to Improve Postsecondary Transition Outcomes for Secondary Students with High Functioning Autism

Company: 3-C Institute for Social Development Agency/Program/Year/Phase: ED / SBIR / 2013 / 1
Abstract: This project team will develop a web-based product to engage 11th and 12th grade high school students with HF-ASD in a self-paced online interactive course to learn about the transition to college, learn specific resilience strategies for coping with the transition to college, and to practice… more

Accommodation integrated technology to minimize the impact of disability on students’ assessment performance

Company: 3-C Institute for Social Development Agency/Program/Year/Phase: ED / SBIR / 2013 / 1
Abstract: There is growing interest in computerized systems to increase accessibility of assessments for students with disabilities. Technology offers an ideal platform for implementing Universal Design (UD) principles for assessment to better accommodate student diversity and support broad student… more

Web-based Tool for the Dissemination of Evidence-Based Interventions for ATOD Pre

Company: 3-C INSTITUTE FOR SOCIAL DEVELOPMENT Agency/Program/Year/Phase: HHS / SBIR / 2013 / 1
Abstract: DESCRIPTION (provided by applicant): Over the past several decades, a large number of evidence-based prevention initiatives for alcohol, tobacco, and other drug (ATOD) use have been rigorously tested and shown to be efficacious. However, despite availability, evidence-based interventions (EBIs) for… more

Neurorestorative Strategy for Diabetic Peripheral Neuropathy

Company: 3-C INSTITUTE FOR SOCIAL DEVELOPMENT Agency/Program/Year/Phase: HHS / SBIR / 2013 / 1
Abstract: DESCRIPTION (provided by applicant): Early childhood research indicates that school readiness is a key determinant of a successful transition to school. Between 9.5% and 14.2% of young children experience social-emotional problems that negatively impact school-readiness, and nearly half of children… more

Droplet-Based Automation of Complex Workflows for Synthetic Biology

Company: ADVANCED LIQUID LOGIC Agency/Program/Year/Phase: DOD / STTR / 2013 / 1
Abstract: Large-scale genome engineering represents a broad group of technologies, all of which stand to impact the manufacturing of a range of biological and chemical products. While the power of these methods to increase the production of biologically-driven manufacturing processes has been previously… more

Automated Sample Preparation for Next Generation Sequencing Cancer Diagnostics

Company: ADVANCED LIQUID LOGIC Agency/Program/Year/Phase: HHS / SBIR / 2013 / 1
Abstract: DESCRIPTION (provided by applicant): As more diverse genetic links are established with cancer, the utility of one-gene-one-test diagnostics is diminished. In addition, biopsies are mixed populations of tumor and normal tissue, requiring deconvolution oftumor and non-tumor genoptypes to accurately… more

Distributed REMD Simulation for Probing Alzheimer Molecular Mechanisms

Company: ADVANCED LIQUID LOGIC Agency/Program/Year/Phase: HHS / SBIR / 2013 / 1
Abstract: DESCRIPTION: Mass spectrometry is a multiplex technology for high-throughput analysis of biomolecules in newborn screening and clinical laboratories. Complexity in sample preparation has been recognized as the main bottleneck in well-established MS methods. Digital microfluidics is a rapidly… more

Point-of-Care Nucleic Acid Test for Cytomegalovirus for Newborn Hearing Screening

Company: ADVANCED LIQUID LOGIC Agency/Program/Year/Phase: HHS / SBIR / 2013 / 1
Abstract: DESCRIPTION (provided by applicant): Universal newborn hearing screening is mandated in the US and is performed in the postpartum hospital setting. Current physiology-based hearing screening tests are unable to detect late-onset hearing loss caused by cytomegalovirus (CMV) infection. Therefore, a… more

Point-of-Care Nucleic Acid Test for Cytomegalovirus for Newborn Hearing Screening

Company: ADVANCED LIQUID LOGIC Agency/Program/Year/Phase: HHS / SBIR / 2013 / 2
Abstract: DESCRIPTION (provided by applicant): Universal newborn hearing screening is mandated in the US and is performed in the postpartum hospital setting. Current physiology-based hearing screening tests are unable to detect late-onset hearing loss caused by cytomegalovirus (CMV) infection. Therefore, a… more

Targeting mutant KRAS for cancer therapy

Company: ALDERON BIOSCIENCES, INC. Agency/Program/Year/Phase: HHS / SBIR / 2013 / 1
Abstract: DESCRIPTION: Lead toxicity is a serious but preventable public health problem in the U.S. and elsewhere in the world. Even at very low levels, ingested lead causes irreversible damage, especially in young children, resulting in decreased IQ, learning disabilities, attention deficit disorders,… more

Coordinated Treatment of Addiction to Prescription Pain Medications

Company: CLINICAL TOOLS, INC. Agency/Program/Year/Phase: HHS / SBIR / 2013 / 1
Abstract: DESCRIPTION (provided by applicant): In 2010, more than 12 million people reported using prescription pain medications (opioids) non-medically (without a prescription) [1], and 2 million people reported using prescription painkillers non-medically for thefirst time [1]. In 2009, 1/3 o people older… more

Virtual Environment Training in the Proper Use of Prescription Pain Medications

Company: CLINICAL TOOLS, INC. Agency/Program/Year/Phase: HHS / SBIR / 2013 / 1
Abstract: DESCRIPTION: (provided by applicant) An epidemic of addiction to prescription pain medications now causes deaths due to overdose that outnumber automobile-related deaths, rising admissions to hospitals, and disrupted lives for both the patient and family.The White House Office of National Drug… more

iPadEMR Pain Management Simulator: Tablet-based Skills Development

Company: CLINICAL TOOLS, INC. Agency/Program/Year/Phase: HHS / SBIR / 2013 / 2
Abstract: DESCRIPTION (provided by applicant): An estimated 116 million US adults suffer from chronic pain at an estimated cost of 635 billion and, unfortunately, existing pain management training is not adequately preparing health professionals to address this area [1]. To address this gap we propose to… more

Clinical Tools, Inc.

Company: CLINICAL TOOLS, INC. Agency/Program/Year/Phase: HHS / SBIR / 2013 / 2
Abstract: Project Goal/Intended Impact: To improve outcomes of in-treatment addicted patients by providing a virtual reality game as part of a regular health care visit with a health care provider. The game can be played with an off- the- shelf commercially available gaming system that can sense and be… more

Novel Drug VS-105 for Treatment of Osteoporosis

Company: COGNOSCI, INC. Agency/Program/Year/Phase: HHS / SBIR / 2013 / 1
Abstract: DESCRIPTION (provided by applicant): Investigational Safety and Toxicity Studies of Subcutaneous COG1410 for Alzheimer's Disease: A Therapeutic Based upon Apolipoprotein-E That is Not Targeted to Amyloid-Beta Background on Alzheimer's Disease: Alzheimer'sDisease (AD) is the leading… more

CDX-301 and Plerixafor Combination in Stem Cell Mobilization for Transplantation

Company: COGNOSCI, INC. Agency/Program/Year/Phase: HHS / SBIR / 2013 / 1
Abstract: DESCRIPTION (provided by applicant): Diabetic peripheral neuropathy (DPN) is one of the most common and devastating complications of diabetes mellitus, affecting more than 50% of diabetic patients, and is the leading cause of foot amputation. DPN, characterized by peripheral axonal degeneration and… more

Fast-Running Physics-Based Models for Intercept Debris Aero-heating and Aero-thermal Demise

Company: Corvid Technologies, Inc. Agency/Program/Year/Phase: DOD / SBIR / 2013 / 1
Abstract: Corvid Technologies is pleased to offer this SBIR Phase I proposal. In the proposed effort, we will develop a fast-running, predictive methodology for the aerothermal demise of the debris generated during a Ballistic Missile Defense intercept event. This model will be informed by existing… more

Advanced Ballistic Shielding for Crew Served Weapons Stations

Company: Corvid Technologies, Inc. Agency/Program/Year/Phase: DOD / SBIR / 2013 / 1
Abstract: In a Phase I effort, Corvid Technologies will develop and test candidates for a series of advanced ballistic shields for crew served weapons stations intended to replace heavy, cumbersome shielding that does not meet required specifications. Current armor production efforts by Corvid will be… more