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STTR Phase I: Site specific delivery of cancer stem cells inhibitory peptides

Company: Thermally Targeted Therapeutics, Incorporated Agency/Program/Year/Phase: NSF / STTR / 2013 / 1
Abstract: This Small Business Research (SBIR) Phase I project tests the application of a thermally responsive biopolymer, simultaneously to deliver breast cancer therapy and to prevent disease recurrence. Encouraging responses to multimodal treatments (surgery, radiotherapy, chemotherapy) are too often… more

Orally Active Formulations of DHA Dimers for the Treatment of Infectious Diseases

Company: ELSOHLY LABORATORIES, INC. Agency/Program/Year/Phase: HHS / STTR / 2013 / 1
Abstract: DESCRIPTION (provided by applicant): The natural product artemisinin is a sesquiterpene endoperoxide with known anti-malarial activity against both chloroquine-sensitive and chloroquine-resistant strains of the parasite Plasmodium falciparum. In addition to its anti-malarial activity, artemisinin… more

Energy Efficient LED Spectrally Matched Smart Lighting

Company: Innovative Imaging and Research Agency/Program/Year/Phase: NASA / STTR / 2013 / 2
Abstract: Innovative Imaging and Research and the University of Houston Clear Lake have teamed to develop a widely extensible, affordable, energy efficient, smart lighting device known as Lambda-Net. Smart building technologies, such as Lambda-Net, are becoming critical to energy savings and sustainability… more

Optimization Using Metamodeling in the Context of Integrated Computational Materials Engineering (ICME)

Company: Predictive Design Technologies Agency/Program/Year/Phase: DOE / STTR / 2013 / 1
Abstract: Predictive Design Technologies, LLC (PDT) proposes to employ Integrated Computational Materials Engineering (ICME) tools to help manufacturing industry in the United States. ICME uses computational materials science tools within a holistic system in order to accelerate materials development, improve… more

Foliage Propagation Model Development to Support New Communications Concepts

Company: MAV6 Agency/Program/Year/Phase: DOD / SBIR / 2012 / 1
Abstract: The Foliage Abstraction RF Multiscale Estimation Rendering (FARMER) framework will perform high fidelity simulations of heavy foliage environments using a novel multiscale approach, dramatically extending the capabilities of existing foliage modeling tools and integrating existing computational… more

Solid Polymer Electrolytes with High Lithium Ion Conductivity and Transport Number for Hybrid Electric Power-train Systems

Company: HYBRID PLASTICS Agency/Program/Year/Phase: DOE / SBIR / 2012 / 1
Abstract: Current energy storage devices have energy densities that are barely sufficient for low cost electric-vehicles and rely on lithium ion batteries that use flammable, unsafe, liquid electrolytes. However, in order to replace liquid electrolyes in lithium batteries for hybrid electric power train… more

SBIR Phase I: Minimizing Vehicle Aero Drag with Optimized Deturbulators

Company: SINHATECH Agency/Program/Year/Phase: NSF / SBIR / 2012 / 1
Abstract: This Small Business Innovation Research Phase I project will cost effectively optimize the integration of Sinhatech's patented flexible-skin Deturbulator with vehicle drag-reducing wind deflectors, aircraft wings and airfoils. The Deturbulator is a passive flexible-skin large-eddy breakup… more

Energy Efficient LED Spectrally Matched Smart Lighting

Company: Innovative Imaging and Research Agency/Program/Year/Phase: NASA / STTR / 2012 / 1
Abstract: Innovative Imaging and Research has teamed with the University of Southern Mississippi to develop a novel energy efficient smart light system. Smart lighting adds an occupancy sensor, photosensor, controller, and dimming unit to a light source and has been shown to save up to 50% of the energy… more

Discrete Geometry Toolkit for Shape Optimization

Company: Optimal, LLC Agency/Program/Year/Phase: NASA / SBIR / 2011 / 2
Abstract: Simulation-based design optimization has been steadily maturing over the past two decades, but not without its own unique and persistent challenges. The proposed project will develop a novel solution to one of the long-standing bottlenecks in simulation-based design optimization. Particularly, we… more

Development of Tetrahydrocannabinol Prodrugs for Topical Treatment of Glaucoma

Company: ELSOHLY LABORATORIES, INC. Agency/Program/Year/Phase: HHS / STTR / 2011 / 1
Abstract: DESCRIPTION (provided by applicant): Currently, FDA approved clinical applications of 9-Tetrahydrocannabinol (THC) include control of nausea and vomiting associated with chemotherapy and for appetite stimulation for AIDS patients suffering from anorexia and wasting syndrome. However, THC also… more

WASP-III Advanced Reconnaissance Device Network (WARDN)

Company: MAV6 Agency/Program/Year/Phase: DOD / SBIR / 2011 / 1
Abstract: The WASP-III Advanced Reconnaissance Device Network (WARDN) is a miniaturized VHF/UHF emitter geolocation system targeted for installation on micro-UAV platforms. The Mav6 design approach of embedded antenna design, compact RF circuit design, and load balancing the signal processing and geolocation… more

POSS TCP Resin System for Carbon Fiber Reinforced Composite Shipboard Applications

Company: HYBRID PLASTICS Agency/Program/Year/Phase: DOD / STTR / 2011 / 1
Abstract: The proposed effort will utilize lithiated POSS in synergistic combination with commercial phosphates to achieve comparable processing characteristics and superior flame retardancy, smoke and toxicity to that of Derakane 510A. The POSS-phosphate synergist package will be formulated into a Hydrex… more

Anion Exchange Polymer Membranes Based on Polyoctahedral Silsesquioxanes for Alkaline Fuel Cells

Company: HYBRID PLASTICS Agency/Program/Year/Phase: DOD / SBIR / 2011 / 1
Abstract: Polyhedral silsesquioxanes (POSS) will be modified using chloromethylation of aromatic POSS cages. These cages will then be co-cast, using solvent, with chloromethylated polysulfones and subsequently quaternized with monofunctional and difunctional trialkylamines in order to render crosslinked films… more

Advanced Thermoelectric Milli-Power Source

Company: Camgian Microsystems Corporation Agency/Program/Year/Phase: DOD / SBIR / 2011 / 1
Abstract: Energy can be harvested or scavenged from many environmental sources such as: solar, wind, vibrations, temperature gradients, etc. Two common issues related to environmental energy sources are limited/unpredictable availability and limited/unpredictable quantity. This proposal examines the… more

Microscopic Traffic Flow Simulation Models - An Open Source Approach

Company: New Global Systems for Intelligent Transportation Management Agency/Program/Year/Phase: DOT / SBIR / 2011 / 2
Abstract: PHASE II TECHNICAL OBJECTIVE The major objective of this Phase II proposal is to establish open source traffic simulation model and software, and to develop application programming interfaces to accommodate future traffic research needs. Objectives will be accomplished by building and demonstrating… more

Multi-Modal Sensor with Real Time Telemetry for Storm Surge and other Meteorological Measurements

Company: Hyperion Technology Group Agency/Program/Year/Phase: DOC / SBIR / 2011 / 1
Abstract: Storm surge poses a grave threat to both life and property as hurricanes make landfall. The ability to monitor surge in real-time using a densely-space network of sensors with integrated data recording and telemetry would provide NOAA with a unique capability. Our approach is to offer a system which… more

Optical Approach to Augment Current Float Sensing Method of Determining Cryogen Fluid Height Within a Tank

Company: Innovative Imaging and Research Agency/Program/Year/Phase: NASA / STTR / 2011 / 1
Abstract: Innovative Imaging and Research, a small technology development company, has teamed with the University of Southern Mississippi Instrument and Cryogenics Research Laboratory to integrate existing NASA Stennis Space Center heritage cryogen level monitoring technology with noncontact optical methods… more

Evaluation of UltraClean Cotton for Nonwovens Application

Company: Wildwood Gin, Inc Agency/Program/Year/Phase: USDA / SBIR / 2010 / 1
Abstract: Domestic textile manufacturing has suffered a sad fate over the course of the last 15 years and competition with imported products has reduced capacity in the U.S. textile and apparel sectors, and the domestic textile industry no longer consumes the majority of the cotton produced in the United… more

Discrete Geometry Toolkit for Shape Optimization

Company: Optimal, LLC Agency/Program/Year/Phase: NASA / SBIR / 2010 / 1
Abstract: Simulation-based design optimization has been steadily maturing over the past two decades, but not without its own unique and persistent challenges. The proposed project will develop a novel solution to one of the long-standing bottlenecks in simulation-based design optimization. Particularly, we… more

Multi-Mechanistic Cosmetic Coating to Protect Skin from Thermal Injury

Company: SciGenesis, LLC Agency/Program/Year/Phase: DOD / SBIR / 2010 / 2
Abstract: SciGenesis will optimize the multi-mechanistic thermally protective cosmetic coating developed during our Phase I efforts in order to maximize thermal protection and impart optimum spreadability, coverage, and stability. The optimized prototype will then become the base formulation for research to… more

Pressure Sensitive Adhesive (PSA) Development

Company: SciGenesis, LLC Agency/Program/Year/Phase: DOD / SBIR / 2010 / 1
Abstract: In this Phase I, SciGenesis is adapting adhesive materials and techniques from our current adhesive projects to the development of a pressure sensitive adhesive that will meet rigorous NAVAIR requirements for military applique coatings. Our group has successfully incorporated stimuli-responsive… more

Method of Locating Unexploded Ordnance

Company: MAV6 Agency/Program/Year/Phase: DOD / SBIR / 2010 / 2
Abstract: UARS (Unexploded ordnance Asset RFID System) is a secure, active radio frequency identification (RFID) system that when equipped to munitions provides a method for underground geolocation in the event that munitions do not explode. Additionally UARS provides a method for authenticated wireless… more

Space and Operational Environmental Protection for Thin Multijunction Solar Cells

Company: HYBRID PLASTICS Agency/Program/Year/Phase: DOD / SBIR / 2010 / 1
Abstract: The recent development of colorless, transparent polyimides provides a break-out solution for the operational and environmental protection of thin multijunction solar cells. The incorporation of polyhedral oligomeric silsesquioxanes into the polyimide backbone renders these systems radiation hard… more

Hemostatic Agent Development

Company: HYBRID PLASTICS Agency/Program/Year/Phase: DOD / SBIR / 2010 / 1
Abstract: The proposed effort comprises a treatment combination using the platelet binding hemostatic capability of Nanoscopic Chemicals known as POSS trisilanols in combination with hyaluronic acid media, and antibiotic drugs in liquid and foam form. Mechanistically, liquid POSS trisilanols are injectable… more

Ultra Low Power Electronics for Autonomous Micro-Sensor Applications

Company: Camgian Microsystems Corporation Agency/Program/Year/Phase: DOD / SBIR / 2010 / 1
Abstract: This program aims to develop an ultra low power System-on-a-Chip (SoC) technology that will enable >10x improvements in size and endurance over current generation wireless micro-sensor networks. This will be achieved through the integration of advanced circuit and architectural design methods… more