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Wireless Physiological and Environmental Monitoring System

Company: Physical Optics Corporation Agency/Program/Year/Phase: DHS / SBIR / 2015 / 2
Abstract: To address the DHS need for a single wireless device that will monitor multiple physiological and environmental conditions of and surrounding a first responder, and relay the information to the incident command, Physical Optics Corporation (POC) proposes to advance the new Wireless Physiological and… more

X-ray Simulation Platform for Explosive Detection Equipment

Company: Triple Ring Technologies Agency/Program/Year/Phase: DHS / SBIR / 2015 / 2
Abstract: This proposed effort will develop the Particle/Ray Interaction Simulation Manager (PRISM) software platform which was begun as a Phase I program. The goal of PRISM is to meet the x-ray simulation needs of the explosive detection community. In Phase I a user survey was conducted of a wide range of… more

Delivering In-Vehicle Messages in Temporary Work Zones

Company: Savari Inc. Agency/Program/Year/Phase: DOT / SBIR / 2014 / 2
Abstract: The primary objective of SBIR Phase II is to design and validate the data flow inside a smart work zone system by designing a framework that would enable exchanging work zone related messages between remote traffic management center server TMCS and the vehicles on the road. The framework will… more

High Gain, High Power PCSS with Integrated Monolithic Optical Trigger

Company: Ness Engineering, Inc. Agency/Program/Year/Phase: DOD / STTR / 2014 / 1
Abstract: The objective of this proposal is to examine the feasibility of a design for a Photoconductive Semiconductor Switch (PCSS) with an integrated optical trigger that can switch at least 30 kV, 1 kA, 20 ns pulses with jitter<100 ps. The PCSS must be triggered without an external laser and the… more

Novel Approaches to Service Virtualization in Mobile Ad Hoc Networks

Company: SUNS-Tech Corp. Agency/Program/Year/Phase: DOD / STTR / 2014 / 2
Abstract: This project focuses on the design and analysis of a scale-free routing approach for mobile ad hoc networks (MANET) that we call automatic incremental routing (AIR), because routing to any destination is automatic from the routing labels assigned to nodes, and incremental in that each node only… more

Prevention of Children's Tympanostomy Tube Otorrhea

Company: O-RAY PHARMA, INC. Agency/Program/Year/Phase: HHS / SBIR / 2014 / 1
Abstract: DESCRIPTION (provided by applicant): Otitis media (infection of the middle ear space) is one of the most common diseases of childhood. Myringotomy with tympanostomy tube (TT) insertion is the most common operation performed on children in the United States. Otorrhea is the most common complication… more

Sustained Release Inner Ear Delivery of Corticosteroid

Company: O-RAY PHARMA, INC. Agency/Program/Year/Phase: HHS / SBIR / 2014 / 2
Abstract: DESCRIPTION (provided by applicant): Cochlear implants have restored hearing in thousands of patients over the last two decades. However, because residual hearing is damaged in the process of insertion, this valuable procedure has been restricted to thosepatients with profound or total deafness.… more

Enzyme Switch: many reporter molecules from a single-molecule-sequencing product

Company: CAERUS MOLECULAR DIAGNOSTICS, INC. Agency/Program/Year/Phase: HHS / SBIR / 2014 / 1
Abstract: DESCRIPTION (provided by applicant): Even as the cost and throughput of commercial sequencers has continued to improve over the last 5 years, there is still a need to further reduce sequencing costs, to increase throughput and sequencing accuracy and to reduce the costs associated with sample… more

Development of Flavivirus Antivirals Targeting Dengue Virus and WNV Protease

Company: CALASIA PHARMACEUTICALS, INC. Agency/Program/Year/Phase: HHS / SBIR / 2014 / 1
Abstract: DESCRIPTION (provided by applicant): Mosquito-borne members of the Flavivirus family include four serotypes of dengue virus (DENV1-4) and West Nile Virus (WNV) and are classified as re-emerging pathogens due to the frequency and severity of recent epidemics. There are an estimated 100 million DENV… more

Frequency-Agile Heterodyne-Driven MMW Signal Generator

Company: RAM Photonics Agency/Program/Year/Phase: DOD / SBIR / 2014 / 2
Abstract: Conventional generation of a high-quality RF carrier (signal) beyond 50GHz requires high precision cavity engineering that inherently restricts contiguous bandwidth coverage. Worse, even if one were capable of fabricating a set of such stabilized, frequency-dense cavities to mimic discrete 30-120GHz… more

Nonlinear-DSP-Enabled RF-Photonic Link

Company: RAM Photonics Agency/Program/Year/Phase: DOD / STTR / 2014 / 1
Abstract: Digital equalizers have been the major enablers in RF communications in terms of managing component imperfections and channel impairments. Specifically, the ever increasing processing power of the dedicating computing processors has availed a steady increase in the ability of complex communication… more

High-Efficiency Polarization-Insensitive Diffraction Grating for All-Glass Monolithic SBC Fiber Laser System

Company: RAM Photonics Agency/Program/Year/Phase: DOD / SBIR / 2014 / 2
Abstract: Spectral beam combination (SBC) of fiber lasers is the most practical approach to DEW-class HELs using diode-pumped fiber lasers. Use of conventional diffraction gratings to combine wavelengths is limited in that metal is inherently absorbing. Regardless of the metal layer thickness, optical power… more

Low-Noise, Parametric, Photonic Oscillator in Short-Wave Infrared (SWIR) Band

Company: RAM Photonics Agency/Program/Year/Phase: DOD / SBIR / 2014 / 2
Abstract: ABSTRACT: In contrast to the NIR band, which is supported by an infrastructure of devices developed to serve telecommunication applications, the SWIR band remains out of reach for critical defense applications. While it is relatively simple to construct a low-noise oscillator within the… more

Ion Channel Screening Using Photoswitches

Company: PHOTOSWITCH BIOSCIENCES, INC. Agency/Program/Year/Phase: HHS / SBIR / 2014 / 1
Abstract: Ion channels are membrane proteins that allow the selective movement of charged molecules through cellular membranes. Many disease states, such as cystic fibrosis, muscular dystrophies, hypertension, and cardiac arrhythmias are caused by ion channel pathologies. Ion channels have been identified by… more

Ion Channel Screening Using Photoswitches

Company: PHOTOSWITCH BIOSCIENCES, INC. Agency/Program/Year/Phase: HHS / SBIR / 2014 / 2
Abstract: DESCRIPTION (provided by applicant): Ion channels are membrane proteins that allow the selective movement of charged molecules through cellular membranes. Many disease states, such as cystic fibrosis, muscular dystrophies, hypertension, and cardiac arrhythmias are caused by ion channel pathologies.… more

High Throughput Data Collection Software for Multiplexed TEM Samples

Company: NANOIMAGING SERVICES, INC. Agency/Program/Year/Phase: HHS / SBIR / 2014 / 1
Abstract: DESCRIPTION (provided by applicant): Transmission electron microscopy is a valuable technique for characterizing biological therapeutics, vaccines, drug delivery vehicles, and nanoparticles. There is considerable evidence that links the physical propertiesof these samples to their bio-distribution,… more

Peripheral administration of nonpeptide somatostatin agonists for ophthalmic dise

Company: CRINETICS PHARMACEUTICALS, INC. Agency/Program/Year/Phase: HHS / SBIR / 2014 / 1
Abstract: Project Summary With an increasing older population, including the generational aging of the baby boomers , age-related eye diseases are common and becoming more prevalent. Currently, it is estimated that 11 million Americans suffer from age-related macular degeneration (AMD) - a number that is… more

Autonomous Characterization Algorithms for Change Detection and Correlation (ACDC)

Company: ExoAnalytic Solutions, Inc Agency/Program/Year/Phase: DOD / SBIR / 2014 / 1
Abstract: ABSTRACT: The modern warfighter requires freedom of action in space for friendly forces, and when necessary, the ability to defeat adversary efforts that interfere or attack US or allied space systems and to negate adversary space capabilities. Freedom of action in space is enabled by Space… more

Integrated Target Characterization Suite Using Multi-Sensor Fusion

Company: ExoAnalytic Solutions, Inc Agency/Program/Year/Phase: DOD / SBIR / 2014 / 2
Abstract: The objective of this effort is to develop and test a multi-sensor data fusion algorithm suite that will fuse information from multiple electro-optic (EO) and radio frequency (RF) sensors to estimate tracked objects physical properties and dynamics for the purpose of aiding in predicting signatures… more

RF/EO Track Correlation and Characterization (RETC2)

Company: ExoAnalytic Solutions, Inc Agency/Program/Year/Phase: DOD / STTR / 2014 / 2
Abstract: In order to counter emerging threats from the Middle East and Southeast Asia, the Ballistic Missile Defense System (BMDS) is acquiring new sensor (e.g. AN/TPY-2 and PTSS type) and weapon technology (SM-3). As these new technologies are fielded, the BMDS's Command, Control, Battle Management… more

Rad-Hard Sigma-Delta 3-Channel ADC for Fluxgate Magnetometers

Company: Pacific Microchip Corporation Agency/Program/Year/Phase: NASA / SBIR / 2014 / 1
Abstract: The proposed project aims to develop a multi-channel analog to digital converter (ADC) required for a fluxgate magnetometer (EPD) employed on NASA's planetary exploration missions. The ADC has to feature very high resolution, radiation hardness (tolerance to SEE and TID), low power consumption… more

Low Power Digital Correlator System for PATH Mission

Company: Pacific Microchip Corporation Agency/Program/Year/Phase: NASA / SBIR / 2014 / 1
Abstract: The NASA's PATH mission employs a synthetic aperture radiometer that produces 768 IF (10MHz - 500MHz) signals. Digitizing the signals results in 1.536Tb/s (1GS/s, 2-bit) data stream. Within the NASA's SBIR contracts NNX12CE50P and NNX13CP01C, Pacific Microchip Corp. has developed a low… more

Integrated Patient Management System for the Improved Treatment of Asthma and Oth

Company: FARUS, LLC Agency/Program/Year/Phase: HHS / SBIR / 2014 / 1
Abstract: DESCRIPTION (provided by applicant): Asthma is increasingly common and expensive. Current estimates place the number of people in the US with asthma at over 25M. Asthma accounts for one-quarter of all emergency room visits in the US. Direct treatment and indirect patient costs rose from 53B in 2002… more

Advanced Infrared Emitter Array (AIREA)

Company: Ostendo Technologies Agency/Program/Year/Phase: DOD / SBIR / 2014 / 1
Abstract: ABSTRACT: Identify approaches to increase spatial resolution of advanced emitter arrays. Provide an analysis of alternatives that evaluates the feasibility of each approach and identifies the best approach to pursue. Provide a system performance prediction for the chosen approach. BENEFIT: … more

Rapid Assembly of Durable Composite Radome Panels and Radome Mounting Interface

Company: Infinite Technologies, Inc Agency/Program/Year/Phase: DOD / SBIR / 2014 / 2
Abstract: ABSTRACT: Current Air Force and industry radome designs are time- and resource-exhaustive, and require frequent maintenance and inspection throughout product lifecycle, due to outdated technologies. Typical panels are constructed with one of several joint types mated to the adjoining panel with… more