First Generation of Controlled-Release Bacteriocins/Anti-Microbials
Company: ORBIS BIOSCIENCES, INC. Agency/Program/Year/Phase: DOD / SBIR / 2012 / 1Abstract: Combat ration Intermediate Moisture (IM) products use low pH and water content (aw) to discourage bacterial growth. The long-term goal of this proposal is to maintain the microbial stability of ration components over a two-year shelf life while increasing the pH and aw values for an improved… more
Precision Particle Fabrication-enabled Betamethasone-loaded Microspheres for Tran
Company: ORBIS BIOSCIENCES, INC. Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1Abstract: DESCRIPTION (provided by applicant): Current approaches to treat sudden sensorineural hearing loss (SSNHL) do not maintain inner ear drug concentrations within an appropriate therapeutic window for sufficient lengths of time to achieve therapeutic effect.A novel delivery system for long-term,… more
Engineering Microparticles for Taste-Masking and Controlled Release of Pediatric
Company: ORBIS BIOSCIENCES, INC. Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1Abstract: DESCRIPTION (provided by applicant): Pediatric drug development presents many unique challenges in the effective treatment of diseases in children, from adequate dosing information and pediatric-specific testing to palatable flavor profiles and effective delivery formats. A novel technology that… more
STRETCH ROLL FORMING
Company: Fairmount Technologies LLC Agency/Program/Year/Phase: DOD / SBIR / 2012 / 2Abstract: During the Phase I SBIR project funded by DLA, Fairmount Technologies (FT) has developed and proven a new CNC metal forming process called stretch roll forming (SRF) that can produce complex parts made out of extrusions without part-specific dies. The proofof- concept machine developed has stretch… more
Electronic Location Reporting for Individuals With Cognitive Disabilities
Company: INTELLISPEAK, LLC Agency/Program/Year/Phase: HHS / SBIR / 2012 / 2Abstract: DESCRIPTION (provided by applicant): The proposed effort is aimed at the development and evaluation of a wireless electronic location system for reporting the location of individuals with autism and other cognitive disabilities, who may wander or elope. This is a very vexing and routine problem for… more
Electronic Location Reporting for Individuals With Alzheimers Disease and other D
Company: INTELLISPEAK, LLC Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1Abstract: DESCRIPTION (provided by applicant): The proposed effort is aimed at the evaluation of a wireless electronic location system for reporting the location of individuals with Alzheimer's Disease and other Dementia (ADOD), who tend to wander or elope. This isa very vexing and routine problem for… more
Electrically Generated Haptic Feedback to Simulate Virtual Explosions
Company: ARC Technology Agency/Program/Year/Phase: DOD / SBIR / 2012 / 1Abstract: This proposal details the development of a variable pulsed power circuit and custom load that simulates the audio, visual, and tactile response of a variety of explosive devices. The system operates by tailoring the voltage and current discharge profile through the stimulus generator at the… more
AirCore Reusable InSitu Sampler for CO2 and Trace Gas Measurements
Company: KALSCOTT Engineering, Inc. Agency/Program/Year/Phase: NASA / SBIR / 2012 / 1Abstract: The AirCore is a simple and novel atmospheric air column sampler to validate satellite observation data of greenhouse gases, using a lightweight, inexpensive coated stainless steel coil. The simple design of the leads to cost savings during manufacture and operation. The addition of a UAV to the… more
Miniature WCDMA Payload
Company: KALSCOTT Engineering, Inc. Agency/Program/Year/Phase: DOD / SBIR / 2012 / 1Abstract: Under U.S. defense policy, the Navy is responsible for delivering satellite communications to"disadvantaged"users, the term for intelligence officials and troops working in remote areas, often with no more resources than backpacks or small vehicles. MUOS is slated to provide coverage for… more
Chemical-Biological Forensic Evidence Container with Agent and Tamper Resistant Tools
Company: NanoScale Materials, Inc. Agency/Program/Year/Phase: DOD / STTR / 2012 / 2Abstract: The proposed research incorporates several inventions to produce structural components that are assembled into a highly enhanced Toxic Material Forensic Container (TMFC) for transport and storage of contaminated articles. Bio-hazardous materials are frequently encountered in investigations, and the… more
Applications and Methods for Continuous Monitoring of Physiological Chemistry
Company: PINNACLE TECHNOLOGY, INC Agency/Program/Year/Phase: DOD / STTR / 2012 / 1Abstract: With the notable exception of glucose, most metabolic biomarkers cannot be accurately, and practically measured over long periods, in vivo and in real-time. A primary reason is stable, selective enzymes suitable for biosensors are not available. Biosensors could revolutionize acute and long-term… more
A non-invasive high-throughput sleep stage analysis system
Company: PINNACLE TECHNOLOGY, INC Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1Abstract: DESCRIPTION (provided by applicant): Degeneration of sleep quality with age is a well-documented phenomenon. While much is known regarding the characterization of this decline, remarkably little of the physiology or genetic underpinnings are understood. Age-related sleep changes in rodents (mice +… more
A Nicotine Biosensor for Addiction Studies
Company: PINNACLE TECHNOLOGY, INC Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1Abstract: DESCRIPTION (provided by applicant): Tobacco-related deaths cost the United States approximately 200 billion each year. Nicotine is singularly responsible for the dependence-forming properties of tobacco smoking and, once introduced to the body, rapidly affects the brain within 15 seconds. Breaking… more
A Tissue Implantable Microbiosensor
Company: PINNACLE TECHNOLOGY, INC Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1Abstract: DESCRIPTION (provided by applicant): The aim of this application is to develop, prototype, validate, manufacture and commercialize a new, generalized microbiosensor designed for non-human use and based on functionalized nanoparticles. The microbiosensors produced will enable in vivo monitoring of a… more
SBIR Phase II: Clean Tool: A unified approach to wafer cleaning
Company: Uncopiers, Inc. Agency/Program/Year/Phase: NSF / SBIR / 2012 / 2Abstract: This Small Business Innovation Research (SBIR) Phase II project aims to develop a single wafer processing clean tool for semiconductor wafer cleaning at all stages of wafer processing. The method relies on using acoustically controlled micro-cavitation to remove on-wafer particles. This is a… more
Innovative high-airflow smokehouse design with novel method of controlling airflow to cook faster&to reduce temperature&color variation
Company: HANSON, ROBERT Agency/Program/Year/Phase: USDA / SBIR / 2012 / 1Abstract: Industrial smokehouses are large forced-air convection batch ovens used to cook and smoke meat products such as bacon, ham, bologna, whole turkeys, chicken breast, snack sticks, jerky, smoked sausage, hotdogs, sliced luncheon meats, and other smoked meats. These huge smokehouses are crucial to the… more
Phosphorus removal from ethanol thin stillage to produce a low phosphorus livestock feed and a valuable granular fertilizer.
Company: KANSAS ENVIRONMENTAL MANAGEMENT ASSOCIATES LLC Agency/Program/Year/Phase: USDA / SBIR / 2012 / 1Abstract: Grain ethanol production byproducts or ?coproducts? are commonly used in modern beef finishing rations. The term distillers grains (DGS) is intended to include these and similar coproducts. The expansion of the ethanol industry has led to the wide spread availability and economic pricing of DGS,… more
SBIR Phase I: High Quality and Low Cost Bulk Aluminum Nitride Substrates for UV LEDs
Company: Nitride Solutions Inc. Agency/Program/Year/Phase: NSF / SBIR / 2012 / 1Abstract: This Small Business Innovation Research Phase I project will investigate the feasibility of growth of high-quality and low-cost bulk aluminum nitride (AlN) substrates by vapor phase deposition. The performance of nitride-based devices, such as light-emitting diodes (LEDs), lasers, and transistors,… more
Hydrogen/Bromine Energy Storage System
Company: TVN Systems, Inc. Agency/Program/Year/Phase: DOE / STTR / 2012 / 1Abstract: "It is our objective to develop a cost effective, durable and reliable hydrogen-bromine flow battery system for small-scale electrical energy storage applications. H2/Br2 flow battery technology has been around for decades, however, the lack of low-cost and durable electrode and membrane materials… more
Hydrogen/Bromine Energy Storage System
Company: TVN Systems, Inc. Agency/Program/Year/Phase: DOE / STTR / 2012 / 2Abstract: "It is our objective to develop a cost effective, durable and reliable hydrogen-bromine flow battery system for small-scale electrical energy storage applications. H2/Br2 flow battery technology has been around for decades, however, the lack of low-cost and durable electrode and membrane materials… more
Multi-day Pain Management Therapy with Novel Injectable Formulation
Company: ORBIS BIOSCIENCES, INC. Agency/Program/Year/Phase: HHS / SBIR / 2011 / 1Abstract: DESCRIPTION (provided by applicant): Our long term goal is to widespread the use of PPF technology for promoting effective production of drug-encapsulating microparticles with uniform size and physical characteristics that can be leveraged to release a specific drug at controlled rates over… more
SBIR TOPIC 294 PHASE I - DEVELOPMENT OF GLYCOSYLATION - SPECIFIC RESEARCH
Company: APTAKON, INC. Agency/Program/Year/Phase: HHS / SBIR / 2011 / 1Abstract: The function of many cancer related proteins is modulated by modifications such as phosphorylation and glycosylation. The development of antibodies that recognize site-specific phosphorylation has vastly improved our understanding of signal transductionand cancer cell physiology and regulation.… more
Best Practices for IntelliDrive Enabled Mobile Application Development
Company: Mygistics Inc. Agency/Program/Year/Phase: DOT / SBIR / 2011 / 1Abstract: The scope of this research initiative addresses what is best practice for delivering mobile applications while ensuring a safe, consistent experience given the differing communications standards, operating systems and hardware limitations of existing and prospective personal communications… more
DEVELOPMENT OF A RAPID IN VITRO SCREENING ASSAY FOR DETECTION OF CANCER BIOMARKERS IN URINE AND BLOOD.
Company: Nanoscale Corporation Agency/Program/Year/Phase: HHS / SBIR / 2011 / 1Abstract: The goal of the project is to develop a rapid in vitro screening assay for detection of cancer biomarkers in urine and blood. The aim is testing and optimization of nanoparticle sensors, based on cyanine dyes that are chemically linked to Fe/Fe3O4 nanoparticles via protease-selective consensus… more
Electro-Optic Terminal Protection for Radar Systems
Company: ARC Technology Agency/Program/Year/Phase: DOD / STTR / 2011 / 1Abstract: Recent advances in directed energy weapons (DEW) require radar systems to implement front door protection against high power signals. Although nonlinear protection elements have been successfully employed in the past, fast ultra wideband (UWB) and high power microwave (HPM) signals are not… more