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Engineering Microparticles for Taste-Masking and Controlled Release of Pediatric

Company: ORBIS BIOSCIENCES, INC. Agency/Program/Year/Phase: HHS / SBIR / 2014 / 2
Abstract: DESCRIPTION (provided by applicant): New dosage forms are needed to address the shortcomings of current practice with regard to administration of medications to pediatric populations. Specifically, in the absence of pediatric-specific products - formulations that are both palatable (to ensure… more

SBIR Phase II: Innovations in manufacturing technology for a probiotic containing Megasphaera elsdenii NCIMB 41125

Company: MEGASTARTER, LLC Agency/Program/Year/Phase: USDA / SBIR / 2014 / 2
Abstract: Use of high-concentrate diets in cattle production is a common practice in the United States to maximize production efficiency, enhance meat quality, and minimize meat and milk cost of production. Transition from high-fiber to high-concentrate diets is challenging and put the animals at risk for… more

Development and Evaluation of the Online and Applied System for Intervention Skills (OASIS) Program for the Supervision of Professionals Working with Young Children with Autism.

Company: Integrated Behavioral Technologies, Inc. Agency/Program/Year/Phase: ED / SBIR / 2014 / 1
Abstract: This project seeks to develop and evaluate a pilot version of the Online and Applied System for Intervention Skills – Supervision (OASIS-S) a cloud-based portal for the supervision of individuals in service fields that require post-degree supervision. Initially two modules (online and skill-based… more

AirCore Reusable InSitu Sampler for CO2 and Trace Gas Measurements

Company: KALSCOTT Engineering, Inc. Agency/Program/Year/Phase: NASA / SBIR / 2014 / 2
Abstract: A novel design for an in situ air sampling sensor for CO2 and trace gases is proposed. The sensor, named AirCore, provides the advantages of existing in situ sensors (e.g. high resolution) but eliminates possible biases in analysis that often originate from imperfect measurement condition. The… more

Miniature Airborne Methane Sensor

Company: KALSCOTT Engineering, Inc. Agency/Program/Year/Phase: NASA / SBIR / 2014 / 1
Abstract: KalScott Engineering, and the subcontractor, Princeton University propose the development and demonstration of compact and robust methane sensor for small Unmanned Aerial Systems (s-UAS) by synthesizing state-of-the-art, laser-based detection methods with the rapidly increasing s-UAS market. The… more

A turn-key optogenetics and electrophysiology measurement system

Company: PINNACLE TECHNOLOGY, INC Agency/Program/Year/Phase: HHS / SBIR / 2014 / 1
Abstract: ABSTRACT Age-related sleep problems such as advanced sleep phase disorder (ASPD) are estimated to affect at least 1% of middle-aged adults and increase in prevalence with age. While the detrimental effects of sleep disruption with aging are well characterized, detailed insights into the molecular… more

Group housing: A robotic system to track and interact with individuals

Company: PINNACLE TECHNOLOGY, INC Agency/Program/Year/Phase: HHS / SBIR / 2014 / 2
Abstract: DESCRIPTION (provided by applicant): Individually housing animals, even for a short period, is known to have a negative influence on behavior, learning ability, and physiology. Group-housed rodents are better able to cope with stress through improved behavioral and physiological responses.… more

Good Natured Food Campus - An Economic and Cultural Engine for the NorthSide Regeneration Plan

Company: RAINBOW ORGANIC FARMS CO Agency/Program/Year/Phase: USDA / SBIR / 2014 / 1
Abstract: A vastly under-served community, located in an impoverished, 1,500-acre tract in the city of St. Louis, Missouri, is in dire need of increased accessibility to nutritious food. Most of the buildings are torn down, decayed, and abandoned. There are no grocery stores selling nutritious, local, and… more

Development of SAgA Therapy for clearance of NMO-IgG in patients with neuromyelit

Company: ORION BIOSCIENCE, INC. Agency/Program/Year/Phase: HHS / SBIR / 2014 / 1
Abstract: DESCRIPTION (provided by applicant): Orion BioScience Inc. has developed a Soluble Antigen Array (SAgA) therapeutic that displays multiple copies of aquaporin-4 epitope for targeted clearance of the auto reactive NMO-IgG antibody in patients with neuromyelitis optica (NMO). The product is intended… more

Phosphorus removal from ethanol condensed thin stillage to produce a profitable, recycled fertilizer, while improving surface water quality.

Company: KANSAS ENVIRONMENTAL MANAGEMENT ASSOCIATES LLC Agency/Program/Year/Phase: USDA / SBIR / 2014 / 2
Abstract: The expansion of the ethanol industry has led to the wide spread availability and economic pricing of distillers grains (DGS), resulting in significant amounts of DGS being commonly included in animal diets. DGS typically replaces corn and protein supplements in the ration, but is has a much higher… more

Applications and Methods for Continuous Monitoring of Physiological Chemistry

Company: Pinnacle Technology, Inc. Agency/Program/Year/Phase: DOD / STTR / 2014 / 2
Abstract: Point of care (POC) diagnostic devices are a well established market but have significant growth opportunities. Stable off-the-shelf biological recognition elements available in a form that can be readily incorporated into POC devices will be essential for wide spread use and deployment. Other… more

Single-injection, self-contained booster vaccine

Company: ORBIS BIOSCIENCES, INC. Agency/Program/Year/Phase: USDA / SBIR / 2014 / 1
Abstract: Vaccination is a particularly powerful weapon in the fight against wide-spread livestock disease. Commercially available vaccines, however, are often difficult and costly for livestock producers to use properly, leaving individual animals - and by extension the global food supply - at risk. More… more

Microstructured Semiconductor Neutron Detector Arrays for Neutron Scattering Measurements

Company: Radiation Detection Technologies, Inc. Agency/Program/Year/Phase: DOE / SBIR / 2014 / 2
Abstract: There is a need for high-resolution, high-efficiency, and high-rate neutron imaging detectors at neutron scattering facilities. The Oak Ridge National Laboratory Spallation Neutron Source neutron scattering instruments the VULCAN Engineering Diffractometer, the TOPAZ Crystal… more

Portable Neutron Spectrometer

Company: Radiation Detection Technologies, Inc. Agency/Program/Year/Phase: DOD / SBIR / 2014 / 1
Abstract: ABSTRACT: Proposed is the development of an advanced solid state neutron spectrometer (NeuKopis) with directional resolve, building from prototype instruments that have demonstrated the art-of-the-possible. The intrinsic neutron detection efficiency of the refined BENEFITS: Low power, solid state,… more

Late Award - Field-Assembled Component-Based Rotor Blades

Company: Wetzel Engineering, Inc. Agency/Program/Year/Phase: DOE / SBIR / 2014 / 2
Abstract: The utility-scale wind industry is evolving towards very large ( & gt;4MW) machines with blades longer than 70m for both land-based and off-shore installations. There is a rapid ramp in cost associated with ground transportation of blades longer than 65m, rising to a threshold that is… more

Fuel-Air Explosive Technologies from Dual-Use Materials

Company: Energetic Materials Research and Enginee Agency/Program/Year/Phase: DOD / SBIR / 2014 / 2
Abstract: ABSTRACT: In our Phase I SBIR work to date, we constructed an implosion system using carefully-designed components and geometries that reproducibly reacts nearly 100% of the JP10 in the test cell. Using ALE3D we have also been able to qualitatively describe the major hydrodynamic processes… more

3-D Smart Aircraft Conceptual Design Tool

Company: Design, Analysis and Reseach Corporation Agency/Program/Year/Phase: DOD / SBIR / 2014 / 1
Abstract: ABSTRACT: Design, Analysis and Research Corporation (DARcorporation) proposes to develop a 3-D visualization and modification environment as well as higher fidelity modeling capability based on defined geometry to be incorporated into the Advanced Aircraft Analysis (AAA) software. AAA is a… more

Improved Accuracy with Reduced Radiation Dose for SPECT MPI

Company: ADAPTIVEPHARMA, LLC Agency/Program/Year/Phase: HHS / SBIR / 2014 / 1
Abstract: PROJECT SUMMARY/ABSTRACT Coronary Artery Disease (CAD) is responsible for an unacceptable death rate, compromised life quality and economic burden to the US healthcare system. SPECT MPI is widely utilized for diagnosing, management and predicting outcomesof patients with CAD. Recent studies… more

Innovative Tactical Bulk Fuel Delivery System Restraint System

Company: Burchell Professional Group Inc Agency/Program/Year/Phase: DOD / SBIR / 2014 / 1
Abstract: A new innovative tactical fuel bulk system restraint system concept was researched and developed. Analysis confirmed that this new restraint system met all military requirements.

Development of a Sorghum Doubled Haploid Breeding System

Company: HEARTLAND PLANT INNOVATIONS Agency/Program/Year/Phase: USDA / SBIR / 2014 / 1
Abstract: Sorghum acres in the United States and around the world are declining. If this trend is to be reversed, new tools for sorghum crop improvement are needed. Sorghum is a naturally drought-tolerant, heat-resistant crop that can play an important role in meeting ever-increasing global needs for food,… more

HIGH VALUE CANOLA PROTEIN FOR BIO-ADHESIVES APPLICATIONS DERIVED FROM CANOLA MEAL

Company: SUNHAI BIOADHESIVE TECHNOLOGIES LLC Agency/Program/Year/Phase: USDA / SBIR / 2014 / 1
Abstract: Shoes, cars, electronics, self-adhesive notes/envelopes, engineered wood composites, coatings and paints are just a few of the many products requiring adhesives.Many adhesives, however,are made from non-renewable petroleum-based materialsraising concernsfor increased petroleum usage and reliance, a… more

Expanding Precision Particle Fabrication Technology for the Widespread Control of

Company: ORBIS BIOSCIENCES, INC. Agency/Program/Year/Phase: HHS / SBIR / 2013 / 2
Abstract: DESCRIPTION (provided by applicant): A critical need currently exists in the pharmaceutical market for microparticles that can accurately and effectively control the release of poorly water-soluble compounds. Although these poorly water-soluble drugs areprojected to have high clinical efficacy,… more

Electro-Optic Terminal Protection for Radar Systems Phase II

Company: ARC TECHNOLOGY LLC Agency/Program/Year/Phase: DOD / STTR / 2013 / 2
Abstract: The potential threat of directed energy weapons (DEW) and other high peak power electromagnetic transient signals require radar systems to implement front door protection against high power signals. Fast ultra wideband (UWB) and high power microwave (HPM) signals are not successfully blocked by… more

Electrically Generated Haptic Feedback to Simulate Virtual Explosions - Phase II

Company: ARC TECHNOLOGY LLC Agency/Program/Year/Phase: DOD / SBIR / 2013 / 2
Abstract: This proposal details the development of a variable pulsed power system and custom load that simulates the audio, visual, and tactile response of a variety of explosive devices. The system operates by tailoring the driver parameters, such as voltage and current discharge profile, through the… more

AirCore Reusable InSitu Sampler for CO2 and Trace Gas Measurements

Company: KALSCOTT Engineering, Inc. Agency/Program/Year/Phase: NASA / SBIR / 2013 / 1
Abstract: A novel design for an in situ air sampling sensor for CO2 and trace gases is proposed. The sensor, named AirCore, provides the advantages of existing in situ sensors (e.g. high resolution) but eliminates possible biases in analysis that often originate from imperfect measurement condition. The… more