Assured Information Sharing in Clouds
Company: InfoBeyond Technology LLC Agency/Program/Year/Phase: DOD / STTR / 2012 / 1Abstract: ABSTRACT: In the future, numerous military database, documentation, and mission-critical information systems will be migrated to the clouds, due to cloud cost-efficiency and accessing flexibility. However, the cloud servers are generally untrusted either for data owners or users. In this proposal,… more
Distributed storage in wireless mesh networks
Company: InfoBeyond Technology LLC Agency/Program/Year/Phase: DOD / SBIR / 2012 / 1Abstract: Simply encrypted data storage is unable to prevent data loss or compromise if the storage device is damaged or compromised by an adversary. Distributed data storage is the alternative that divides the original data into fragments and secretly stored them on distributed devices with certain… more
Scalable Dynamic Matrix Completion for Information Processing and Link Discovery
Company: InfoBeyond Technology LLC Agency/Program/Year/Phase: DOD / SBIR / 2012 / 2Abstract: We investigate a problem of significant practical importance, namely, the recovery of the data matrix from a partial set of its entries that are collected in a noisy environment (i.e., a noisy partial matrix). Our proposed Near-Optimal Matrix Completion (NOMC) target to provide a leading approach… more
An Innovative Software Tool for Blades Stress Estimation during Multiple Simultaneous Vibratory Mode
Company: Advanced Dynamics, Inc. Agency/Program/Year/Phase: DOD / STTR / 2012 / 1Abstract: ABSTRACT: ADI and ASU propose to develop a novel methodology for blade peak stress prediction from limited strain gage/tip-timing measurements when multiple vibratory modes are present. The current protocol assumes that only one mode is present and only provides upper and lower bound estimates of… more
Transdermal Naltrexone for Opiate Addiction and Alcoholism
Company: ALLTRANZ, INC. Agency/Program/Year/Phase: HHS / STTR / 2012 / 1Abstract: DESCRIPTION (provided by applicant): According to the National Survey of Drug Use and Health (NSDUH) of 2008, 7.2 million Americans are in need of treatment for Substance-Related Disorders (SRDs), and a large proportion of those need treatment for opiate pain reliever, heroin, and alcohol addiction.… more
Competency-based Adaptive Training System
Company: Tier 1 Performance Solutions, LLC Agency/Program/Year/Phase: DOD / SBIR / 2012 / 1Abstract: TiER1 Performance Solutions proposes to develop CATS (Competency-based Adaptive Training System), a system to address common warfighter training needs in the Air and Space Operations Center. A major goal of this effort is to prepare warfighters for mission readiness by integrating a Learning… more
Computational Modeling aided Near Net Shape Manufacturing for Aluminum Alloys
Company: ATI, INC. Agency/Program/Year/Phase: NASA / SBIR / 2012 / 1Abstract: This program will focus on developing and validating computational models for near-net shape processing of aluminum alloys. Computational models will be developed for deformation modeling and for texture generation. Characterization of two aluminum alloys including flow stress, forgeability, and… more
Long-Term Broad-Spectrum Prevention of Implant-Related Infections
Company: BIOMEDICAL DEVELOPMENT CORPORATION Agency/Program/Year/Phase: HHS / STTR / 2012 / 1Abstract: DESCRIPTION (provided by applicant): Deep wound infection following total joint arthroplasty is a devastating complication for physician and patient, a leading cause of morbidity, and a significant economic burden to the healthcare system. With an aging population and increased life expectancies,… more
Vestibular-Topographical Memory Markers for Those At Risk for Alzheimer's Disease
Company: BIOMEDICAL DEVELOPMENT CORPORATION Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1Abstract: DESCRIPTION (provided by applicant): Despite years of research, the cause of Alzheimer's disease remains essentially unknown. Topographic memory impairments are arguably the earliest cognitive deficits observed in Alzheimer's disease, and the brain areas involved in topographic memory are… more
FastFES Neural Prothesis for Stroke Ambulation and Rehabilitation
Company: CUSTOMKYNETICS, INC. Agency/Program/Year/Phase: HHS / SBIR / 2012 / 2Abstract: DESCRIPTION (provided by applicant): This FastTrack SBIR proposal aims to disseminate a Functional Electrical Stimulation (FES) technology for stroke ambulation and neuromotor rehabilitation. The FastFES paradigm integrates two rehabilitation approaches,fast-paced treadmill walking and FES, in a… more
Device for Delivery of Rolipram to Liver for Treatment of Alcoholic Liver Disease
Company: ENDOPROTECH, INC. Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1Abstract: DESCRIPTION (provided by applicant): Alcoholic Liver Disease (ALD) remains a leading cause of death from liver disease in the U.S., and there is still no FDA-approved therapy. Abnormal cytokine metabolism is a major feature of ALD. Elevated serum concentrations of tumor necrosis factor (TNF-) and… more
Delivery of Polyphenols in Gum for Treatment of Gingivitis
Company: FOUR TIGERS, LLC Agency/Program/Year/Phase: HHS / STTR / 2012 / 2Abstract: DESCRIPTION (provided by applicant): Periodontitis represents a polymicrobial disease, in which a complex microbial ecology that matures in biofilms in the subgingival sulcus triggers a chronic immune-inflammatory lesion that destroys soft and hard tissues of the periodontium. Despite the great… more
Simple, Low Cost, Rapidly Deployable System for Forming Ultra High Performance Concrete (UHPC) in the Field.
Company: NuForm Materials, LLC Agency/Program/Year/Phase: DOD / SBIR / 2012 / 1Abstract: We propose the development of a simple, low cost technology for the field placement of ultra-high performance concrete (UHPC) that consists of a modified Gunite system and an improved UHPC formulation. The Gunite system includes modifications that overcome a number of problems related to the… more
Enhancing mammalian glycoprotein production in the baculovirus expression vector
Company: PARATECHS CORP. Agency/Program/Year/Phase: HHS / SBIR / 2012 / 2Abstract: DESCRIPTION (provided by applicant): The baculovirus expression vector system (BEVS) is a proven, powerful and versatile method of eukaryotic protein expression. It is used to produce vaccines, diagnostics, and biologically active proteins for a multitudeof research projects. Like all expression… more
Delayed Tolerance Induction in Living Related Donor Renal Transplant Recipients
Company: REGENEREX, LLC Agency/Program/Year/Phase: HHS / STTR / 2012 / 1Abstract: DESCRIPTION (provided by applicant): We have developed a protocol that reproducibly induces transplantation tolerance in individuals undergoing a living related donor kidney transplant. Three subjects have been off all immunosuppression for 10 months, 2 months, and 1 month respectively and have… more
Development of a Plasma Biomarker of Alzheimer's Disease
Company: SCOUT DIAGNOSTICS Agency/Program/Year/Phase: HHS / STTR / 2012 / 1Abstract: DESCRIPTION (provided by applicant): The major barriers to preventing or treating Alzheimer's disease (AD) are its unknown pathogenesis/etiology and the lack of an objective, sensitive and specific biomarker of the disease, particularly at the early stageswhen therapeutic interventions would… more
Counterpulsation Device with Integrated EKG System for Chronic Partial Circulator
Company: SCR, INC. Agency/Program/Year/Phase: HHS / SBIR / 2012 / 2Abstract: DESCRIPTION (provided by applicant): Heart failure (HF) remains one of the largest unsolved problems in health care today and continues to increase in incidence and cost ( 34.8 billion in US in 2008). Prognosis remains limited especially in patients with advanced heart failure. Transplantation is… more
BIOMARKER FOR EARLY DETECTION OF CHRONIC KIDNEY DISEASE
Company: SEQUELA Agency/Program/Year/Phase: HHS / SBIR / 2012 / 2Abstract: DESCRIPTION (provided by applicant): There are an estimated 26 million Americans with early chronic kidney disease (CKD). Early diagnosis and treatment are the only cost-effective means to reverse this growing problem. NIH recognizes the challenge to diagnose CKD early during its initiation and… more
Flame-Assisted Flash Sintering of Ceramic Coatings for Heat Exchangers
Company: nGimat, LLC Agency/Program/Year/Phase: DOD / SBIR / 2012 / 1Abstract: ABSTRACT: nGimat proposes to develop a novel technique to sinter ceramic films deposited onto metallic substrates by combining two efficient and inexpensive techniques: flame sintering and field-assisted"flash"sintering. The creativeness of this approach lies in the concept to use a… more
Development of Double Lumen Cannula for Percutaneous Right Heart Support
Company: W-Z BIOTECH, LLC Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1Abstract: DESCRIPTION (provided by applicant): Left ventricular assist devices (LVADs) are increasingly applied to treat advanced heart failure, demonstrating improvement of morbidity/mortality and quality of life. Right heart failure (RHF) affects up to 40% of LVADpatients and significantly contributes to… more
A Contaminant Tolerant Solvent for Carbon Capture in Existing Coal-Fired Power Plants
Company: Green Technology Ltd Co. Agency/Program/Year/Phase: DOE / STTR / 2012 / 2Abstract: In the context of post-combustion CO2 capture processes, solvents with fast CO2 absorption rates will require more energy for regeneration. This challenge is exacerbated when aqueous solvents are applied to the capture of post-combustion CO2 from a utility gas stream, which contains such unique… more
Biological vector control reducing arboviruses, including Dengue and Chikungunya
Company: MosquitoMate, Inc. Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1Abstract: DESCRIPTION (provided by applicant): In the absence of effective, approved vaccines or therapeutic measures against dengue and other mosquito borne pathogens, public health efforts must focus on the control of mosquito vectors that are required for transmission. Unfortunately, effective control… more
Cost Effective Seawater Desalination With ICP Element Arrays
Company: Okeanos Technologies, LLC Agency/Program/Year/Phase: EPA / SBIR / 2012 / 1Abstract: Okeanos Technologies is developing a desalination system that used Ion Concentration Polarization (ICP) elements and modular arrays. ICP can separate water from solutes and contaminants far more efficiently than Reverse Osmosis (RO) or Electrodialysis(ED) because no extreme hydraulic pressures or… more
Development of a Novel Therapeutic for Alzheimer' Disease
Company: COPLEX THERAPEUTICS, LLC Agency/Program/Year/Phase: HHS / STTR / 2012 / 1Abstract: DESCRIPTION (provided by applicant): Traditional approaches to drug development for Alzheimer's disease are becoming increasingly expensive and in many cases disappointingly unsuccessful. Based on preliminary in vitro and in vivo studies we have identifieda novel lactam derivative of the… more
SBIR Phase I: No Heat Spray Drying Technology
Company: ZoomEssence, Inc. Agency/Program/Year/Phase: NSF / SBIR / 2012 / 1Abstract: This Small Business Innovation Research (SBIR) Phase I project aims to eliminate the use of heat during the process of spray drying liquid emulsions into powders. Typically, a liquid emulsion consists of a high-value liquid ingredient emulsified with a carrier system that when dried captures the… more