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Decision Making under Uncertainty for Dynamic Spectrum Access

Company: InfoBeyond Technology LLC Agency/Program/Year/Phase: DOD / STTR / 2014 / 1
Abstract: ABSTRACT: Due to scarcity of spectrum, Dynamic Spectrum Access (DSA) becomes a needed technology to improve the utilization of electromagnetic spectrum for DoD satellite communication. However, current DSA approaches are developed for terrestrial communications without addressing the unique… more

Secure Efficient Cross-domain Protocols

Company: InfoBeyond Technology LLC Agency/Program/Year/Phase: DOD / STTR / 2014 / 1
Abstract: ABSTRACT: Coordinating and sharing information across multi-level security (MLS) networks are of great interest in many military applications. However, it is very challenging to accomplish those goals due to the heterogeneous security classifications of different network domains. The recent… more

Circulating Blood-Based Diagnostic for Mild Cognitive Impaired Victims

Company: ADVANCED GENOMIC TECHNOLOGY, LLC Agency/Program/Year/Phase: HHS / SBIR / 2014 / 2
Abstract: DESCRIPTION (provided by applicant): This project aims to generate blood tests for: 1. mild cognitive impairment (MCI), and 2. conversion risk from MCI to full-blown Alzheimer's disease (AD). We have reported that systemic footprints, increases in key micro- RNA (miR) levels, are identifiable… more

Synthetic Language Interface Toolkit for Chat (SynChat)

Company: TiER1 Performance Solutions, LLC Agency/Program/Year/Phase: DOD / SBIR / 2014 / 2
Abstract: ABSTRACT: The ability to access high-quality training anywhere and anytime continues to grow in importance due to the complex nature of operational team environments. Training simulations that use virtual agents that respond and behave like live teammates enhance training and help achieve… more

Common Situation Awareness Tool (CSAT)

Company: TiER1 Performance Solutions, LLC Agency/Program/Year/Phase: DOD / STTR / 2014 / 1
Abstract: Tier1 Performance Solutions proposes to develop CSAT (Common Situation Awareness Tool), a solution that supports more effective event integration and task management, in order to improve situation awareness and knowledge sharing for missile defense system users and stakeholders. At the core of the… more

SBIR Phase I: Educators' Coach for Learner Interventions and Performance Strategies

Company: TiER1 Performance Solutions, LLC Agency/Program/Year/Phase: NSF / SBIR / 2014 / 1
Abstract: This SBIR Phase I project proposes to develop a novel electronic performance support system (EPSS), the Educators' Coach for Learner Interventions and Performance Strategies (E-CLIPS), to aid faculty in the design of online learning content. The face of higher education is dramatically changing… more

Selective Availability Anti-Spoofing Module (SAASM) Compliant GPS Receiver for GEO

Company: Minerva Systems & Technologies, LLC Agency/Program/Year/Phase: DOD / SBIR / 2014 / 1
Abstract: The objective of this proposal is to develop Selective Availability Anti-Spoofing Module (SAASM) compliant GPS receiver for Geosynchronous Earth Orbit (GEO) applications. In this proposal, we explore an approach to design the GEO GPS SAASM receiver based on improved techniques for signal acquisition… more

Novel flavonoids as anti-inflammatory agents in alcoholism

Company: NAPROGENIX, INC Agency/Program/Year/Phase: HHS / SBIR / 2014 / 1
Abstract: DESCRIPTION (provided by applicant): Flavonoids are ubiquitous secondary metabolites in plants with many known health benefits, which are mostly ascribed to their potent anti-oxidant activity. However, a search for novel nicotinic ligands, using high throughput pharmacological screening of a… more

Harvesting specific plant metabolites from hairy root cultures using magnetized n

Company: NAPROGENIX, INC Agency/Program/Year/Phase: HHS / STTR / 2014 / 1
Abstract: DESCRIPTION: Plants produce a wide variety of valuable bioactive metabolites, but these are commonly present in low concentrations in the wild-type plant. This makes the separation and purification of these compounds complicated and expensive. The applicant company, Naprogenix Inc, has developed a… more

SBIR Phase I: A novel biological method to suppress Bacillus thuringiensis (Bt) Toxin resistance

Company: Paratechs Corp. Agency/Program/Year/Phase: NSF / SBIR / 2014 / 1
Abstract: The broader impact/commercial potential of this Small Business Innovation Research (SBIR) Phase I project is the development of a technology to sustain the efficacy of transgenic plants expressing the Bacillus thuringiensis (Bt) toxin. Transgenic expression of Bt toxins is a major tool for the… more

Development of SVAD System for HF Therapy

Company: SCR, INC. Agency/Program/Year/Phase: HHS / SBIR / 2014 / 1
Abstract: DESCRIPTION (provided by applicant): The objective of this proposal is to complete the engineering development and pre-clinical testing of the SCR SVAD system to provide partial cardiac assist in patients with less advanced stage heart failure (HF). HF isincreasing worldwide and represents a major… more

SBIR Phase I: Measurement and Control of Mass and Velocity Rates in Bulk Solids Distribution Systems

Company: Tribo Flow Separations, LLC Agency/Program/Year/Phase: NSF / SBIR / 2014 / 1
Abstract: This Small Business Innovation Research (SBIR) Phase I project demonstrates the feasibility of using a new, non-invasive vibroacoustic method that simultaneously measures solids and air flow rates within highly-branched pneumatic conveyance piping. The method determines characteristic vibrations of… more

Novel reporter cell lines for neurotoxicant assays

Company: TRANSPOSAGEN BIOPHARMACEUTICALS, INC. Agency/Program/Year/Phase: HHS / SBIR / 2014 / 1
Abstract: DESCRIPTION (provided by applicant): While it has been demonstrated that gene mutations are associated with an increasing number of neurodegenerative syndromes, environmental neurotoxicants remain a key factor in the etiology of many such diseases. For example, exposure to pesticides such as maneb… more

Novel method to create knockout rats using endonucleases and spermatogonial stem

Company: TRANSPOSAGEN BIOPHARMACEUTICALS, INC. Agency/Program/Year/Phase: HHS / SBIR / 2014 / 2
Abstract: DESCRIPTION (provided by applicant): The laboratory rat is a preferred rodent model in pre-clinical drug studies. Their larger size facilitates procedures otherwise difficult in mice, includng studies using instrumentation, blood sampling, and surgeries, and allows for ten times the amount of tissue… more

SBIR Phase II: Advanced Hydrodesulfurization Catalysts

Company: Advanced Energy Materials, LLC Agency/Program/Year/Phase: NSF / SBIR / 2014 / 2
Abstract: The broader impact/commercial potential of this Small Business Innovation Research (SBIR) Phase II project is in removing sulfur compounds from various fuels such as diesel, gasoline and mixture of refined fuels known as transmix. It is critically important to reduce sulfur levels below 10 ppm as… more

Development of TransApical to Aorta Double Lumen Cannula for a Neonate LVAD

Company: W-Z BIOTECH, LLC Agency/Program/Year/Phase: HHS / SBIR / 2014 / 1
Abstract: DESCRIPTION (provided by applicant): Left ventricular assist device (LVAD) support allows the neonate with congenital heart disease or cardiomyopathy to grow to a larger body weight that is more feasible for complex surgical correction or heart transplant.A paracorporeal LVAD, the Berlin heart ExCor… more

Development of an effective non-antibiotic dry-off agent for the dairy industry

Company: AMELGO Agency/Program/Year/Phase: USDA / SBIR / 2014 / 2
Abstract: Intramammary infection (a.k.a., mastitis) is the largest attributable cause of lost productivity, discarded milk, chronic morbidity, and prophylactic antibiotic use in the dairy industry. The majority of new infections are associated with the dry period, during which the udders are temporarily… more

Biological vector control reducing arboviruses, including Dengue and Chikungunya

Company: MOSQUITOMATE, INC. Agency/Program/Year/Phase: HHS / SBIR / 2014 / 2
Abstract: DESCRIPTION (provided by applicant): In the absence of effective, approved drugs or vaccines, vector control remains the only means of intervention for many against mosquito-borne diseases. This problem grows more complex with the recent establishment of multiple exotic mosquito species and… more

Electro-Optic and Infrared Situational Awareness Display

Company: Hitron Technologies Agency/Program/Year/Phase: DOD / SBIR / 2014 / 1
Abstract: To address a Navy need for a high resolution full color situational awareness displays to optimize human interface for Navy personnel, ships, and crafts, Hitron Technologies Inc. proposes to develop a see-through full color transparent flexible display with collaboration of Liquid Crystal Institute… more

Exosomal drug formulations

Company: 3P BIOTECHNOLOGIES, INC. Agency/Program/Year/Phase: HHS / STTR / 2014 / 1
Abstract: DESCRIPTION (provided by applicant): More people in the U.S. (160,340 per year) die of lung cancer than of prostate, breast, and colon cancer combined. The most common type of lung cancer, non-small-cell lung cancer (NSCLC), accounts for 75% of all lung cancers. Regrettably, 85% of all patients… more

STTR Phase I: A Student Centered Adaptive Learning Engine

Company: TutorGen, Inc. Agency/Program/Year/Phase: NSF / STTR / 2014 / 1
Abstract: This STTR Phase I project proposes to develop and validate a student centered adaptive learning engine that is focused on improving learning outcomes using data collected from new and existing educational technology projects combined with advanced technology to automatically generate adaptive… more

STTR Phase I: A Novel Abdominal Stimulator to Assist with Ventilator Weaning in Patients

Company: Liberate Medical LLC Agency/Program/Year/Phase: NSF / STTR / 2014 / 1
Abstract: The broader impact/commercial potential of this Small Business Technology Transfer (STTR) Phase I project, in which a new device and approach to weaning patients from mechanical ventilation is proposed, is a reduction in public health care expenditure and a reduction in morbidity for the half a… more

High Power, Long Endurance MnO2/CFx Battery for Sonobuoys Based on Interpenetrating Conductive Network

Company: Nanowise LLC Agency/Program/Year/Phase: DOD / SBIR / 2014 / 1
Abstract: The need for the United States Navy to maintain a superior global Anti-Submarine Warfare capability is heavily dependent on sonobouys and Navy has identified a need to develop batteries to power sonobuoys which have higher power capabilities than currently used technology. Nanowise LLC proposes to… more

Rapid Synthetic Environment Tool for Virtual Battlespace 2 (VBS2)

Company: enomalies Agency/Program/Year/Phase: DOD / SBIR / 2014 / 1
Abstract: This proposal is in response to rapid modeling need in our military force. We plan to develop and demonstrate a framework that will allow warfighters to rapidly acquire and edit geospecific terrain databases, including both building exterior and interiors. The output of our models will be in… more

SBIR Phase I: A Novel Approach to Cholesteatoma Treatment

Company: MICROBIAL ROBOTICS, LLC Agency/Program/Year/Phase: NSF / SBIR / 2014 / 1
Abstract: This Small Business Innovation Research (SBIR) Phase I Project will develop the first non-surgical cure for cholesteatoma. Cholesteatomas are congenital or acquired lesions of the temporal bone that primarily affect the middle ear and mastoid. These lesions are highly destructive and can cause… more