Multi-Robot Systems for Subsurface Planetary Exploration
Company: Astrobotic Technology, Inc. Agency/Program/Year/Phase: NASA / STTR / 2012 / 1Abstract: The proposed innovation is a heterogeneous multi-robot team developed as a platform for effective subsurface planetary exploration. State-of-art robotic exploration is based on single-robot systems with human controllers augmented by limited automation. This system requires near-constant… more
Development of Wnt Pathway Inhibitors for Colorectal Cancer
Company: STEMSYNERGY THERAPEUTICS, INC. Agency/Program/Year/Phase: HHS / SBIR / 2012 / 2Abstract: DESCRIPTION (provided by applicant): StemSynergy Therapeutics Inc. (SSTI) is a biopharmaceutical company focused on the discovery, development, and commercialization of drugs that target pathways fundamental to stem cells and cancer stem cells. The WorldHealth Organization estimates that over 12… more
Targeting stem cell populations in lung cancer by modulating the Wnt and p53 path
Company: STEMSYNERGY THERAPEUTICS, INC. Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1Abstract: DESCRIPTION (provided by applicant): Despite significant advancements in modern medicine with regards to surgery, radiation therapy and imaging of tumors, the survival rate for patients with non-small-cell lung carcinoma (NSCLC) remain almost identical to20 years ago. Current therapies targeting the… more
SBIR Phase I: Online High Fidelity 3D Modeling of Produce Using Low Cost Sensors
Company: Neya Systems, LLC Agency/Program/Year/Phase: NSF / SBIR / 2012 / 1Abstract: This Small Business Innovation Research (SBIR) Phase I project investigates the feasibility of employing high?resolution, colorized, 3D models of food produce captured with structured light technology to identify (ID) and sort produce by quality. The feasibility of accomplishing this within the… more
Target Localization Using Multi-Static Sonar with Drifting Sonobuoys
Company: Scientific Innovations, Inc Agency/Program/Year/Phase: DOD / SBIR / 2012 / 2Abstract: A novel yet mature technique will be used to assimilate coherent-source multistatic ASW data obtained from drifting acoustic sources and receivers. We will demonstrate the technique's ability to correctly estimate the locations of drifting buoys from acoustic data only even when the buoys may… more
SBIR Phase II: Software-as-a-Service Customized Machine Translation for Commercial Language Service Providers and Their Clients
Company: Safaba Agency/Program/Year/Phase: NSF / SBIR / 2012 / 2Abstract: This Small Business Innovation Research Phase-II project develops advanced technology capabilities for constructing and deploying client-adapted automated language translation systems within commercial settings that are used by globalizing enterprises and the language service provider companies… more
Long Term Implantable ICP Monitor for Hydrocephalus Patients
Company: NEURODX DEVELOPMENT, LLC Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1Abstract: DESCRIPTION (provided by applicant): This Phase I SBIR will develop ICPCheck, the first long term implantable, non-invasively readable intracranial pressure (ICP) monitor for hydrocephalus patients. This device will result in improved clinical management of hydrocephalus by providing a rapid and… more
Development of manufacturing technology for the practical application of specialized and environmentally sensitive nutrients, enzymes, immune-stimulating compounds and biologics to aquafeeds
Company: Zeigler Brothers, Inc. Agency/Program/Year/Phase: DOC / SBIR / 2012 / 1Abstract: Zeigler Bros., Inc. (ZBI) has teamed with Harrisvaccines, Inc. (HV) to develop a new aquafeed manufacturing platform for the practical application of underutilized feed additives. These include enzymes, immune-stimulating compounds and biologics that require specialized protection to ensure they… more
Controlled Release of Topical Nitric Oxide for Treating Cutaneous Injuries
Company: Zeomedix Agency/Program/Year/Phase: DOD / SBIR / 2012 / 2Abstract: In this proposal Zeomedix proposes to develop a dressing for infected trauma wounds based on its zeolite encapsulating nitric oxide (NO) technology. Nitric oxide has been shown to enhance the wound healing process as well as act as a powerful antibacterial agent. However, delivery of nitric oxide… more
Novel Formulation of Flu Vaccine for the Aged
Company: DMX, INC. Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1Abstract: DESCRIPTION (provided by applicant): In the US, about 36,000 deaths occur each year due to influenza and its associated diseases, and 85% of these deaths are in the elderly population. Immunization with flu vaccine is considered the best way to prevent seasonal epidemics and pandemics of influenza.… more
Robust and Efficient Anti-Phishing Techniques
Company: Wombat Security Technologies Agency/Program/Year/Phase: DOD / SBIR / 2012 / 2Abstract: Phishing fools end-users into disclosing sensitive information or downloading malware. Commercially available solutions have shown limited success in stopping these attacks. We aim to refine and commercialize novel anti-phishing email and web filtering techniques that overcome these limitations.… more
Innovative High Temperature Heat Pipes for Spacecraft Nuclear Fission Systems
Company: Advanced Cooling Technologies, Inc. Agency/Program/Year/Phase: NASA / SBIR / 2012 / 1Abstract: NASA Glenn is examining small fission reactors for future space transportation and surface power applications. The reactors would have an 8 to 15 year design life that could be available for a 2020 launch to support future NASA science missions. Both 1 kWe thermoelectric and 3 kWe Stirling systems… more
Passivation Coatings for RF Power Devices
Company: Advanced Cooling Technologies, Inc. Agency/Program/Year/Phase: DOE / SBIR / 2012 / 2Abstract: This project aims to increase the reliability of radio frequency (RF) devices used in accelerator facilities by reducing/eliminating corrosion and erosion produced from the high purity de-ionized water cooling systems. Although metal interconnects are required for electrical and thermal … more
Hybrid Solar Coal Gasifier
Company: Advanced Cooling Technologies, Inc. Agency/Program/Year/Phase: DOE / SBIR / 2012 / 1Abstract: This Small Business Innovation Research project proposes to develop a first-of-its-kind hybrid solar-coal gasification technology. The current direct heating gasification technology has two shortcomings: (1) greenhouse gases, resulted from the coal combustion, diluting the syngas product, and… more
Electrical and Thermal Coupled Fast SiC Device Model for Circuit Simulations
Company: Advanced Cooling Technologies, Inc. Agency/Program/Year/Phase: DOD / SBIR / 2012 / 1Abstract: Silicon carbide (SiC) based devices are currently under investigation for their improved efficiency and high thermal stability. Compared to silicon, SiC has an exceptionally high thermal conductivity and also exhibits better mechanical properties. However, limited research has been performed on SiC… more
A Non-Catalytic Fuel Flexible Reformer
Company: Advanced Cooling Technologies, Inc. Agency/Program/Year/Phase: DOD / SBIR / 2012 / 1Abstract: The proposed SBIR Phase I program will develop an innovative fuel flexible reformer for a portable Solid Oxide Fuel Cell (SOFC) power generation system used in the battlefields. The fuel reformer is non-catalytic and can operate with different fuels including methanol, propane, and JP fuels,… more
Adaptive VCS Condenser with Integrated VCHPs for Aircraft Thermal Management
Company: Advanced Cooling Technologies, Inc. Agency/Program/Year/Phase: DOD / SBIR / 2012 / 1Abstract: ABSTRACT: Next-generation aircraft are experiencing increasing thermal challenges due to heat generation from avionics, as well as requirements to lift this heat to temperatures high enough for rejection from the platform. Efforts have demonstrated vapor compression systems (VCS) offer a… more
Heat-pipe Embedded Foam Exhaust Recovery System
Company: Advanced Cooling Technologies, Inc. Agency/Program/Year/Phase: DOD / SBIR / 2012 / 1Abstract: This Small Business Innovation Research Phase I project will develop an advanced thermoelectric generator (TEG) that will improve the overall efficiency of 100-kW class generator sets (gensets). Advanced Cooling Technologies, Inc. (ACT) proposes a novel thermoelectric generation system to convert… more
Development of a Small Molecule Inhibitor for EBV Latent Infection
Company: VIRONIKA, LLC Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1Abstract: DESCRIPTION (provided by applicant): The goal of this SBIR research program is to develop a novel small molecule inhibitor of latent Epstein-Barr Virus (EBV) infection. EBV is a ubiquitous gamma- herpesvirus that has been classified by the World Health Organization as a human carcinogen. Vironika,… more
Treatment of Inflammatory Bowel Disease with Ceramidase Inhibitors
Company: APOGEE BIOTECHNOLOGY CORPORATION Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1Abstract: DESCRIPTION (provided by applicant): The goal of this program is to develop novel inhibitors of human neutral ceramidase (ASAH2) that are effective as therapeutic agents for Inflammatory Bowel Diseases (IBDs). Sphingolipids are being increasingly recognized as key mediators of inflammation, and are… more
Mobile Software for Assisting Individuals in Overcoming Urinary Incontinence
Company: TOUCHTOWN, INC. Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1Abstract: DESCRIPTION (provided by applicant): There is a hidden epidemic of urinary incontinence (UI) in the United States. Thirteen to twenty million Americans suffer from UI, including 10% to 30% of women and 1.5% to 5% of men. Ten percent of women have symptomsso severe that they undergo surgery for UI or… more
ALEXSA Standardization for Clinical Use
Company: ASSESSMENTS ILLUSTRATED Agency/Program/Year/Phase: HHS / STTR / 2012 / 2Abstract: DESCRIPTION (provided by applicant): This STTR Phase II application is to finalize the one-of-its-kind Assessment of Liability and Exposure to Substance use and antisocial behavior(c) (ALEXSA(c)) for educator, pediatric, prevention and epidemiology uses. The ALEXSA system, first funded by a NIDA… more
SBIR Phase I: Non-Invasive Intracranial Pressure Monitor
Company: Third Eye Diagnostics, Inc. Agency/Program/Year/Phase: NSF / SBIR / 2012 / 1Abstract: This Small Business Innovation Research (SBIR) Phase I project proposes to develop a noninvasive intracranial pressure (ICP) monitor based on a pilot clinical study correlating ocular blood pressure and blood flow parameters to ICP. The proposed novel device will combine several standard medical… more
Urban Forestry Modeling and Prioritization Tools
Company: Avencia Incorporated Agency/Program/Year/Phase: USDA / SBIR / 2012 / 2Abstract: The Urban Forestry Modeling and Prioritization Tools project addresses the research and tasks necessary for creating cost effective, web-based software that assists urban foresters with strategically selecting planting locations in order to maximize impact on both the environment and local… more
Experimental and Analytical Techniques for the Validation of Complex Gas Turbine Engine Rotor Systems
Company: BLADE DIAGNOSTICS CORP. Agency/Program/Year/Phase: DOD / SBIR / 2012 / 1Abstract: Develop a low-cost high cycle fatigue experimental and analytical capability to evaluate complex gas turbine engine rotor and airfoil systems for the purpose of component and design tool validation.