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Technology for Removal of Heavy Metals and Arsenic from Juice

Company: XPLOSAFE, LLC Agency/Program/Year/Phase: USDA / SBIR / 2014 / 1
Abstract: The discovery that many fruit juices and brown rice syrup contain significant concentrations of arsenic or heavy metals such as lead and cadmium has raised concern amongst the public, government regulators, and food and juice producers. This contamination occurs both from natural and anthropogenic… more

A Wnt Modulator for Treatment of Age-related Macular Degeneration

Company: CHARLESSON, LLP Agency/Program/Year/Phase: HHS / SBIR / 2014 / 1
Abstract: PROJECT SUMMARY/ABSTRACT Age-related macular degeneration (AMD) is characterized by progressively decreased central vision and visual acuity and remains a leading cause of vision loss and blindness in aged Americans. Currently, the standard of care for AMD is intravitreal vascular endothelial… more

Quantum Dot Mid-Wave Infrared Focal Plane Array

Company: Nanolight, Inc. Agency/Program/Year/Phase: DOD / STTR / 2014 / 1
Abstract: The objective of this proposal is to develop novel lead salt semiconductor quantum dot (QD) mid-infrared detectors for sensing and imaging applications. The proposed development is based on our recent study of PbSe photoconductive (PC) detector with a rec

Development of a Novel IR Detector for Improved CO2 Subsurface Sequestration Monitoring

Company: Amethyst Research, Inc. Agency/Program/Year/Phase: DOE / SBIR / 2014 / 1
Abstract: Low cost and accurate monitoring of sequestered gases such as CO2 is critical to insure that sequestered gases are not reentering the atmosphere. Management requires, in part, improved atmospheric and ground monitoring of greenhouse gases through sensors capable of measuring the flux,… more

Low Dark Current, Extended Wavelength SWIR Sensors Using Hydrogenated Unipolar Barrier InGaAs

Company: Amethyst Research, Inc. Agency/Program/Year/Phase: DOD / SBIR / 2014 / 2
Abstract: In this Phase II program, improved performance SWIR sensors with extended wavelength response to 2.5 microns will be developed using two disruptive technologies, which Amethyst has successfully demonstrated in the Phase I program: unipolar barrier (e.g., nBn) detector structures, and defect… more

Fluorescent Lateral Flow Assay for Diagnosis of Cocciodioidomycosis

Company: IMMUNO-MYCOLOGICS, INC. Agency/Program/Year/Phase: HHS / SBIR / 2014 / 1
Abstract: Coccidioidomycosis, also known as Valley Fever, is a disease caused by inhalation of Coccidioides arthroconidia. This disease is endemic to the southwestern United States, parts of Mexico, and Central and South America. Every year approximately 150,000 people in the United States become infected… more

Rabbit InMAD Discovery of Novel Biomarkers for POC Tuberculosis Diagnostic Assay

Company: IMMUNO-MYCOLOGICS, INC. Agency/Program/Year/Phase: HHS / STTR / 2014 / 1
Abstract: DESCRIPTION (provided by applicant): Tuberculosis (TB) is a chronic infectious disease that infects approximately one-third of the world's population. Eighty-five percent of the estimated 9.4 million new cases of TB in 2008 occurred in resource-limited countries located in Asia and Africa. In… more

Small blood pumps for small patients

Company: VADOVATIONS, INC. Agency/Program/Year/Phase: HHS / SBIR / 2014 / 1
Abstract: PROJECT SUMMARY/ABSTRACT Heart failure and congenital heart defects threaten the lives of several thousand children each year. The only FDA-approved long term pediatric heart support device is the Berlin Heart Excor, which is based on 30+ year old technology and is fraught with complications… more

STTR Phase I: Sensulin AVT: A 24-hour glucose-responsive insulin

Company: Sensulin, LLC Agency/Program/Year/Phase: NSF / STTR / 2014 / 1
Abstract: This Small Business Technology Transfer (STTR) Phase I project?s primary objective is to develop a glucose-responsive platform for 24-hour delivery of insulin for type 1 and type 2 diabetes, which will cover the patient?s entire daily dose in a single administration. The company?s drug delivery… more

Mannheimia haemolytica outer membrane vesicle-based vaccine for Shipping Fever in cattle

Company: SOLIDTECH ANIMAL HEALTH, INC. Agency/Program/Year/Phase: USDA / SBIR / 2014 / 1
Abstract: "Shipping Fever" is the main cause of illness/death in beef cattle in North America, resulting in & gt;$500 million/year of losses due to treatment costs, poor weight gain, reduced carcass value and death. Mannheimia haemolyticabacteria causes the most serious form of shipping fever,… more

STTR Phase I: Efficient Mid-Infrared Interband Cascade Lasers

Company: Applied Quantum Enovation LLC Agency/Program/Year/Phase: NSF / STTR / 2014 / 1
Abstract: This Small Business Technology Transfer (STTR) Phase I project will develop efficient interband cascade lasers based on innovative hybrid waveguides using dielectric and metal layers. The hybrid-waveguide interband cascade lasers will be much less demanding in the growth of device structures and… more

Detectors with Improved Near-to-Mid IR Performance and Reduced Cooling Requirements

Company: Amethyst Research Inc. Agency/Program/Year/Phase: NASA / STTR / 2014 / 2
Abstract: This program will develop an ultra-high performance infrared detector manufacturing technology with improved performance and cost effectiveness, and reduced cooling requirements when compared to the best commercially available HgCdTe and InGaAs detectors. This will be accomplished using a… more

SBIR Phase I: Development of long service life vacuum insulation composites

Company: MaxQ Research LLC Agency/Program/Year/Phase: NSF / SBIR / 2014 / 1
Abstract: This Small Business Innovation Research Phase I project is focused on development of a novel manufacturing method for producing compartmentalized vacuum composites that exhibit superior thermal and structural efficiency. The proposed efforts will enable mass production of these materials and… more

Multiple Mechanism (MULTIMECH) Body Armor

Company: TechVen Technologies, LLC Agency/Program/Year/Phase: DOD / SBIR / 2014 / 1
Abstract: Body armor used today is an achievement of modern science, constructed of high tensile strength, manmade fibers and ultra hard, impervious ceramics. As impressive as this armor is, however, one of the most critical areas of armor testing methodology has remained largely unchanged from its National… more

Label-free platform for applications in drug discovery

Company: SENSIQ TECHNOLOGIES, INC. Agency/Program/Year/Phase: HHS / SBIR / 2014 / 2
Abstract: DESCRIPTION: Incremental improvements in label free screening technologies over the past decade have not produced the capability necessary to support the changing needs of drug discovery programs. Persistent artifacts related to non-specific binding, promiscuous binding, precipitation, complex… more

Scale-Up of ATPE Technology to Produce Highly Enriched Semiconducting SWCNTs

Company: SouthWest NanoTechnologies (SWeNT) Agency/Program/Year/Phase: DOC / SBIR / 2014 / 1
Abstract: Single-walled carbon nanotubes (SWCNTs) have unique material properties making them very attractive for use in a variety of electronic applications. However, as-grown SWCNTs contain a mixture of tubes with heterogeneous optical and electronic properties. The chiral species must be separated in order… more

Work Tool Innovation for Farm Land Management and Wildfire Abatement

Company: HILL MANUFACTURING, INC. Agency/Program/Year/Phase: USDA / SBIR / 2014 / 1
Abstract: For rural farmers and ranchers with small and mid-sized operations who suffer losses in efficiency due to unproductive pastures and damage and property loss due to wild fires, the envisioned tree saw is an auxiliary tractor attachment with the potential to rapidly and safely remove large trees,… more

HIGH PRESSURE MONOLITH ELECTROOSMOTIC PUMP

Company: MicroChem Solutions Agency/Program/Year/Phase: DOE / STTR / 2014 / 2
Abstract: The objective of lab-on-chip (LOC) is to integrate and perform multiple analytical processes on a microchip platform. So far, most LOC research has been focused on electrophoretic separations. Limited progress has been made on multi-process integration, due mainly to the lack of a robust and… more

Proactive Methodology for Identifying Problem Aerospace Parts

Company: Anautics, Inc. Agency/Program/Year/Phase: DOD / SBIR / 2013 / 2
Abstract: ABSTRACT: The proposed solution would provide the United States Air Force (USAF) a thin client application for proactively identifying problem parts. Our solution is dependant on a digital Bill of Materials (BOM) which we also provide a tool for importing and loading the cleansed parts structure… more

Developing A Novel Therapy for Diabetic Retinopathy

Company: CHARLESSON, LLP Agency/Program/Year/Phase: HHS / SBIR / 2013 / 1
Abstract: DESCRIPTION (provided by applicant): Diabetic retinopathy (DR) is a common complication of diabetes and a leading cause of vision loss in the United States. Unfortunately, there is no FDA-approved pharmacotherapy for DR. Current treatments in clinical practice and trails, such as laser… more

Expanding Precision Particle Fabrication Technology for the Widespread Control of

Company: TRANSTIMULATION RESEARCH, INC. Agency/Program/Year/Phase: HHS / SBIR / 2013 / 1
Abstract: DESCRIPTION (provided by applicant): Diabetes affects more than 8% of Americans and costs over 174 billion in 2007 in USA. Recently bariatric surgery, such as Roux-en-Y gastric bypass, has been proposed for treating diabetic patients with obesity due to its hypoglycemic effect on postprandial blood… more

ULTRA-HIGH PERFOMANCE SOLID-STATE REFRIGERATION USING II-VI LOW DIMENSIONAL STRUCTURE

Company: Amethyst Research, Inc. Agency/Program/Year/Phase: DOD / SBIR / 2013 / 1
Abstract: ABSTRACT: This program targets development of a high-performance thermoelectric (TE) cooler with a figure-of-merit, ZT>3, which greatly exceeds currently available technology. The cooler is fabricated using Group II-VI compound semiconductors, i.e. HgCdSe or HgCdTe, using a low dimensional… more

Detectors with Improved Near-to-Mid IR Performance and Reduced Cooling Requirements

Company: Amethyst Research, Inc. Agency/Program/Year/Phase: NASA / STTR / 2013 / 1
Abstract: This STTR Phase I proposal addresses a NASA need for improved near-to-mid IR detectors for imaging and spectroscopy. High performance IR detectors with cutoff wavelengths in the range of 2.5?5.0 microns will be developed using InGaAs / AlAsSb semiconductor materials. The proposal uses a two-pronged… more

Immunoassay for diagnosis of invasive fungal disease

Company: IMMUNO-MYCOLOGICS, INC. Agency/Program/Year/Phase: HHS / STTR / 2013 / 1
Abstract: DESCRIPTION (provided by applicant): Early diagnosis of infectious disease is critical to patient outcome. An important early question is - is it a fungus, a bacterium or a virus? A rapid answer to this question would allow preemptive treatment that cansave lives. The goal of this project is a… more

Flow Cytometry Assay for Detection of Cryptococcal Antigen

Company: IMMUNO-MYCOLOGICS, INC. Agency/Program/Year/Phase: HHS / SBIR / 2013 / 2
Abstract: Cryptococcal meningitis (CM) kills more than 600,000 HIV-infected individuals globally per year, with the highest yearly incidence occurring in sub-Saharan Africa. There is a critical need for a simple diagnostic tool for cryptococcosis that can be used in resource-limited countries. An innovative… more