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Intracellular Detection of Small Molecules in Live Cells

Company: Agave BioSystems, Inc. Agency/Program/Year/Phase: DOD / STTR / 2014 / 2
Abstract: ABSTRACT: Protection of first responders who are exposed to hazards including chemical warfare agents (CWAs) is a very critical need. The need is derived from not only their welfare but their ability to respond, protect the community and provide logistical support to the response. A simple… more

Intracellular Detection of Small Molecules in Live Cells

Company: Agave BioSystems, Inc. Agency/Program/Year/Phase: DOD / STTR / 2014 / 2
Abstract: ABSTRACT: Protection of first responders who are exposed to hazards including chemical warfare agents (CWAs) is a very critical need. The need is derived from not only their welfare but their ability to respond, protect the community and provide logistical support to the response. A simple… more

Intracellular Detection of Small Molecules in Live Cells

Company: Agave BioSystems, Inc. Agency/Program/Year/Phase: DOD / STTR / 2014 / 2
Abstract: ABSTRACT: Protection of first responders who are exposed to hazards including chemical warfare agents (CWAs) is a very critical need. The need is derived from not only their welfare but their ability to respond, protect the community and provide logistical support to the response. A simple… more

Reworkable Epoxy Bonding for Superconductor Multi-chip Modules

Company: HYPRES. Inc. Agency/Program/Year/Phase: DOD / STTR / 2014 / 2
Abstract: HYPRES, in collaboration with University of Arkansas (UA), proposes to develop a method for manufacturing superconductor multi-chip modules (MCMs) using nano-engineered cryogenic adhesives. A superconductor MCM comprises a carrier and several flipped chips. Before final assembly on the carrier,… more

SBIR Phase I: Novel Zeolite Membranes for Olefin/Paraffin Separation

Company: Bettergy Corp. Agency/Program/Year/Phase: NSF / SBIR / 2013 / 1
Abstract: This Small Business Innovation Research Phase I project proposes to develop a highly permeable inorganic membrane for olefin/paraffin separation. Zeolite membranes have a number of advantages over polymer membranes and other inorganic membranes, including greater chemical and mechanical stability,… more

Carbon Aerogel Natural Gas Sorbent Energy Storage Material

Company: Ceralink, Inc. Agency/Program/Year/Phase: DOE / SBIR / 2013 / 1
Abstract: Unprecedented reserves of natural gas have recently been unlocked from previously uneconomical shale formations in the United States, leading to a rapid decline in the price of this fossil fuel energy source. In the U.S., natural gas vehicle utilization has been limited by several factors, including… more

Wind Tunnel High Temperature Heater Element

Company: C9 Corporation Agency/Program/Year/Phase: DOD / SBIR / 2013 / 1
Abstract: ABSTRACT: C9 Proposes to Develop a high Temperature Heating Element to Augment the Wind Tunnel at AEDC. The element will be fabricated by molding a creamic composite molding compound using methods developed for other defense and commercial applications. The element will be capable of surface… more

Light Weight, Scalable Manufacturing of Telescope Optics

Company: ReliaCoat Technologies, LLC Agency/Program/Year/Phase: NASA / SBIR / 2013 / 1
Abstract: NASA's future X-ray astronomy missions will require X-ray optics that have large effective areas, are lightweight, and cost effective. Recent X-ray telescopes, such as the Chandra Observatory, utilized reflectors made from zerodur which were up to 20mm thick. The thickness of the reflector as… more

SBIR Phase I: Bioactive, High-Strength Contrast Agents for Orthopedic and Bone Applications

Company: Transparent Materials, LLC Agency/Program/Year/Phase: NSF / SBIR / 2013 / 1
Abstract: This Small Business Innovation Research (SBIR) Phase I project seeks to develop bioactive, high-strength contrast agents for use in orthopedic and bone implant applications. There is a clear clinical need for improved contrast agents that increase the strength, toughness and abrasion wear of… more

SBIR Phase I: Innovative Modified Microbial Surfactants: Biobased Solutions for Industrial and Environmental Applications

Company: Synthezyme Agency/Program/Year/Phase: NSF / SBIR / 2013 / 1
Abstract: This Small Business Innovation Research Phase-I project will address the development of modified sophorolipid (MSL) surfactant molecules by simple and scalable modification of natural SLs adopting "green chemistry principles". Natural SLs will be produced through fermentation with yeast… more

SBIR Phase I: Designing an Immune System Response Into High-Temperature Ceramic Matrix Composite Materials (CMC)

Company: Free Form Fibers L.L.C. Agency/Program/Year/Phase: NSF / SBIR / 2013 / 1
Abstract: This Small Business Innovation Research Phase I project is designed to evaluate a novel interphase nanocoating designed for Silicon Carbide (SiC) fibers, which is intended to behave as a biomimetic immune system for high-temperature Ceramic Matrix Composites (CMCs) exposed to an oxidizing… more

High Fidelity Digital Human Models for Protective Equipment Design

Company: CRYE ASSOCIATES LLC Agency/Program/Year/Phase: DOD / STTR / 2013 / 2
Abstract: Today the evaluation methods employed in the development and assessment of soldier borne Personal Protective Equipment (PPE) system designs are often extremely slow, expensive, and subjective, resulting in significant delays and expense in the fielding of improved designs. Recent rapid advancements… more

Diamond Beam Flux, Timing and Position Monitors for Synchrotron Radiation Facilities

Company: Sydor Instruments, Llc Agency/Program/Year/Phase: DOE / SBIR / 2013 / 2
Abstract: The effectiveness of synchrotron radiation science has been hindered by the limited availability of advanced diagnostics. In many cases, the capability to produce photon fluxes has outpaced the ability to detect and measure the resultant photons. Synchrotron applications are becoming more… more

A Low Cost Modular Approach to Flight Testing of Hypersonic Systems

Company: Acent Laboratories Llc Agency/Program/Year/Phase: DOD / SBIR / 2013 / 2
Abstract: ABSTRACT: Airbreathing hypersonic weapon systems utilizing ramjet/scramjet and/or combined cycle engines will open the door to many new capabilities for the warfighter. Applications include systems ranging from small tactical hypersonic missiles, hypersonic intelligence, surveillance &… more

A Design Study for Megawatt Class Waveguide Input Coupler for Synchrotron Light Source Superconducting Cavities

Company: Advanced Energy Systems, Inc Agency/Program/Year/Phase: DOE / SBIR / 2013 / 1
Abstract: Modern synchrotrons are providing higher beam currents and demanding more RF power from the superconducting cavities. The maximum RF power available without beam is limited by the maximum power rating of the WR1800 waveguide RF ceramic window used in the fundamental power coupler. Operation at… more

Ultrafast Electron Diffraction Device for Time-Resolved Chemical Imaging

Company: Advanced Energy Systems, Inc Agency/Program/Year/Phase: DOE / SBIR / 2013 / 1
Abstract: Because of the need to operate in a space-charge-dominated regime, the generation and preservation of femtosecond electron beams is a major challenge for chemical dynamics and accelerator technology R & amp;D. Electrons from a photo-cathode radio frequency (RF) gun can be used as scattering … more

Developing Rugged, High Quantum Efficiency, Graphene Photocathodes

Company: Advanced Energy Systems, Inc Agency/Program/Year/Phase: DOE / SBIR / 2013 / 1
Abstract: Photocathodes have been the focus of intense experimental and theoretical development for many decades, and their use in RF photoinjectors has been indispensible for the evolution of light sources such as free-electron lasers. At present there is a significant science and technology gap for… more

In-Service Fatigue Loads Data Gathering with CSG

Company: Advanced Global Services Agency/Program/Year/Phase: DOD / SBIR / 2013 / 2
Abstract: ABSTRACT: A direct sensing of stress and fatigue and their visualization is very attractive and has been pursued for decades. Prognostica is a new and unique tracking, sensing, and prognosticating technology that allows for exactly that. Based on the results achieved in the Phase I effort it is… more

High-capacity and Cost-effective Manufacture of Chloroperoxidase

Company: Agave BioSystems, Inc. Agency/Program/Year/Phase: DOD / STTR / 2013 / 2
Abstract: The chloroperoxidase enzyme from the filamentous fungus Caldariomyces fumago has applications in industrial chemical synthesis and the detection and inactivation of chemical warfare agents. Chloroperoxidase is capable of regio- and enantioselective oxygenations and halogenations of organic… more

Multiplex Immunoassays in the Development of Vaccines Against Enteric Pathogens

Company: Agave BioSystems, Inc. Agency/Program/Year/Phase: DOD / SBIR / 2013 / 2
Abstract: Bacterial enteric pathogens causing travelers"diarrhea (TD) in developing countries include enterotoxigenic E. coli (50%), Camplyobacter jejuni, Shigella sonnei and Shigella flexneri, while Norovirus is a common viral cause. High risk regions for TD include areas where US service members are… more

Probiotics for Maintaining Dolphin (Tursiops truncatus) Health and the Readiness of the U.S. Navy"s Marine Mammal Systems

Company: Agave BioSystems, Inc. Agency/Program/Year/Phase: DOD / STTR / 2013 / 1
Abstract: Agave BioSystems, with their academic partners at the Mote Marine Laboratory, proposes to develop probiotic pharmaceuticals from indigenous commensal microbes to enhance gastrointestinal health in the bottlenose dolphin (Tursiops truncatus). The dolphin gastrointestinal microbiome will be… more

SBIR Phase I: Quantifying consumer rationale expressed in free text online discussions

Company: dMetrics Inc. Agency/Program/Year/Phase: NSF / SBIR / 2013 / 1
Abstract: This Small Business Innovation Research (SBIR) Phase I project aims at developing a targeted semantic processing framework for the analysis of online conversations. A particular focus is given to improving the state-of-the art in the design of semi-supervised syntactic and semantic parsers capable… more

Advanced Software Defined Radio Capabilities and Information Dominance - Applying ANDRO"s Transmission Cyberspace Solution

Company: ANDRO Computational Solutions, LLC Agency/Program/Year/Phase: DOD / SBIR / 2013 / 1
Abstract: This proposed research is to investigate and validate Software Defined Radio (SDR) based, multi-function portable network sensing and intrusion detection algorithms suitable for small dismounted radio platforms used to support Command and Control (C2) standard sensor interfaces carried in the field… more

Automated Target Characterization and Correlation with Heterogeneous Kinematic and Feature Data for Sensor Hand-Over

Company: ANDRO Computational Solutions, LLC Agency/Program/Year/Phase: DOD / SBIR / 2013 / 1
Abstract: We propose to develop and implement a set of algorithms within a unified target characterization and correlation framework capable of operating in a multiple heterogeneous sensor environment where detection, classification, localization and track priority information is exchanged among multiple… more

Graphics Processing Unit (GPU) Acceleration for Cosite Interference Prediction Tools

Company: ANDRO Computational Solutions, LLC Agency/Program/Year/Phase: DOD / SBIR / 2013 / 1
Abstract: Simulation tools that exist today for prediction of cosite interference in complex RF environments are able to accurately model complex platforms but they are quickly constrained by computational limits on traditional workstations. The focus of this research will be on updating existing… more