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Next-Generation Micro-chip Carrier for Cooling of Satellite Payload Electronics

Company: ThermAvant Technologies, LLC Agency/Program/Year/Phase: DOD / SBIR / 2014 / 2
Abstract: ABSTRACT: A chip carrier for high power density electronics made from low CTE materials and embedded with an oscillating heat pipe will be applied to a real world satellite electronics device to transform high heat flux (e.g. 100-300W/cm2) at the device package to a lower heat flux at the heat sink… more

Tumor-toxic CD47 mAb therapy for leukemia: a proof of concept study

Company: VASCULOX, INC. Agency/Program/Year/Phase: HHS / STTR / 2013 / 1
Abstract: DESCRIPTION (provided by applicant): CD47 has emerged as a novel therapeutic target in hematologic cancers. Leukemias expressing the highest levels of CD47 have the worst prognosis. Increased CD47 expression is thought to protect cancer cells from phagocytic clearance by sending a don't eat me… more

Anti-CD47 mAb Therapy to Improve Kidney Transplantation

Company: VASCULOX, INC. Agency/Program/Year/Phase: HHS / SBIR / 2013 / 2
Abstract: DESCRIPTION (provided by applicant): Organ transplantation is a lifesaving option for those with end stage renal disease. In spite of many improvements in organ procurement, transplant procedures and immune suppression, the damage done by ischemia-reperfusion injury (IRI) remains problematic,… more

Magnetic Flow Sorter for Pancreatic Islet Isolation

Company: APT THERAPEUTICS, INC. Agency/Program/Year/Phase: HHS / SBIR / 2013 / 1
Abstract: DESCRIPTION (provided by applicant): Bone metastasis is common in patients with advanced breast, prostate, and lung cancers as these tumors have a remarkable ability to metastasize to bone. Two-thirds of patients with metastatic bone cancer experience severe pain which is usually described as dull… more

Thermal Management Improvements for Transmit/Receive Modules

Company: ThermAvant Technologies, LLC Agency/Program/Year/Phase: DOD / SBIR / 2013 / 1
Abstract: An oscillating heat pipe (OHP) embedded substrate made from low coefficient of thermal expansion (CTE) material(s) will be designed, simulated, optimized, fabricated, and empirically tested to demonstrate the OHP technology's ultra-high heat transfer rates under real-world microchip operating… more

Cylindrical Geometry Energy Storage Cooling Architectures

Company: ThermAvant Technologies, LLC Agency/Program/Year/Phase: DOD / SBIR / 2013 / 1
Abstract: ThermAvant Technologies, LLC and University of Texas at Arlington propose to design, model, fabricate and empirically test conformal fitting cylindrical energy storage heat cooling packages. ThermAvant will optimize cylindrical battery array cooling solutions that balance size, weight, coolant flow… more

Reconstruction Algorithms for High-Energy Computed Tomography Images of Rocket Motors

Company: Lickenbrock Technologies LLC Agency/Program/Year/Phase: DOD / SBIR / 2013 / 2
Abstract: ABSTRACT: High Energy X-ray computed tomography (CT) is used to inspect the integrity of solid rocket motors. The purpose of this proposal is to improve the detection of defects when they are obscured due to physical limitations of CT. Lickenbrock has developed an advanced variant of the… more

Property/Composition Model for Phosphate Glasses Containing Hanford AZ102 LAW

Company: MO-SCI Corporation Agency/Program/Year/Phase: DOE / STTR / 2013 / 1
Abstract: Nuclear power is a key component in the strategy to meet the countrys energy goals and technologies are needed to improve the reliability of current reactors and disposing safely of nuclear wastes. Vitrification is considered the preferred process for nuclear waste disposal and the U.S. Department… more

Computational tools to analyze SNP data from patients with mental illness

Company: PARTEK, INC. Agency/Program/Year/Phase: HHS / SBIR / 2013 / 2
Abstract: DESCRIPTION (provided by applicant): The broad, long-term objective of the proposed research is to develop and market a commercial software product that can be used to facilitate the analysis of genetic changes in order to elucidate chromosomal abnormalities that underlie diseases such as autism… more

Optical Instruments for Non-Intrusive Off-Body Measurements in Hypersonic Flight Experiments

Company: Innovative Technology Applications Co., Agency/Program/Year/Phase: DOD / STTR / 2013 / 2
Abstract: ABSTRACT: Under this Small Business Technology Transfer (STTR) program, Innovative Technology Applications Company (ITAC), LLC and the University of Notre Dame (UND) are working to develop new optical instruments that will enable nonintrusive, off-body measurements of flow parameters in hypersonic… more

Non-Lethal Munitions for Defeating Improvised Explosive Devices (IEDs)

Company: Loki, Incorporated Agency/Program/Year/Phase: DOD / SBIR / 2013 / 1
Abstract: The objective of the proposed research and development work is to create non-lethal munitions that generate high-power microwave (HPM) pulses to defeat the electronics used to activate Improvised Explosive Devices (IEDs) or to attack blasting caps to pre-detonate IEDs. To provide the best Phase I… more

SBIR PHASE II TOPIC 294, DETECTION OF PROTEIN GLYCOSYLATION; HHSN261201300047C; P

Company: MEDIOMICS, LLC Agency/Program/Year/Phase: HHS / SBIR / 2013 / 2
Abstract: Not Available

Laser Cleaning of Optics and Coatings for High Energy Laser Applications

Company: MetaStable Instruments, Inc. Agency/Program/Year/Phase: DOD / SBIR / 2013 / 1
Abstract: Attenuated total internal reflection laser cleaning will be investigated as a solution to DPAL window contaminantion.

3 kW High Performance Permanent Magnet Alternator

Company: QM Power, Inc Agency/Program/Year/Phase: DOD / SBIR / 2013 / 2
Abstract: QM Power will design, build and test a high performance 3kW alternator using Parallel Path Magnetic Technology (PPMT) with no at risk rare earth magnet materials that is smaller, lighter and more efficient than the existing alternator that uses rare earth magnets. The Parallel Path Magnetic… more

Plasma Fairings for Quieting Aircraft Landing Gear Noise

Company: Innovative Technology Applications Co. Agency/Program/Year/Phase: NASA / SBIR / 2013 / 1
Abstract: A major component of airframe noise for commercial transport aircraft is the deployed landing gear. The noise from the gear originates due to complex, unsteady bluff body flow separation from gear components and the subsequent multiple interactions of unsteady wakes with downstream undercarriage… more

Identification of Landing Gear Aeroacoustic Noise Sources with the Synthetic Array Technique

Company: Innovative Technology Applications Co. Agency/Program/Year/Phase: NASA / SBIR / 2013 / 1
Abstract: In this program, Innovative Technology Applications Company (ITAC), LLC and collaborators propose to advance "synthetic phased array" technology to improve understanding of noise from landing gear. The technology, initially developed in a previous NASA SBIR project for trailing edge noise,… more

Lightweight Fiber Reinforced Transparent Composites for Armored Ground/Sea Vehicles

Company: Habsonic LLC Agency/Program/Year/Phase: DOD / SBIR / 2013 / 1
Abstract: The main objective of this work is to develop and commercialize light-weight transparent composites with high tensile strength, toughness and impact resistance. Novel techniques will be developed for the design and manufacturing of these lightweight composite materials with improved blast resistance… more

Mesodissection Device Phase II

Company: MEDSOCKET OF MISSOURI, INC. Agency/Program/Year/Phase: HHS / SBIR / 2013 / 1
Abstract: DESCRIPTION (provided by applicant): Physicians, no matter how well prepared, generate an average of two clinical questions per every three patient encounters. In 2009, the 1.3 billion visits to physicians' offices, hospital outpatient departments, and hospital emergency departments produced… more

SBIR Phase I: MyCCMajors: A Knowledge-Based System to Improve Student Advisement at Two Year Colleges

Company: Townsend Communications, Inc Agency/Program/Year/Phase: NSF / SBIR / 2013 / 1
Abstract: This Small Business Innovation Research (SBIR) Phase I project seeks to improve academic advisement for seven million community college students. Advisement is a major weakness in student progress toward degree completion. The research determines whether an Internet-based advisement instrument that… more

SBIR Phase I: Securing Industrial Control Networks with Network Forecasting

Company: Observable Networks, LLC Agency/Program/Year/Phase: NSF / SBIR / 2013 / 1
Abstract: The innovation of network forecasting is a new approach to securing industrial control networks that is based upon 1) discovering, monitoring, and modeling all devices on a network, 2) using these models to predict future device behavior, 3) evaluating past predictions with current observations of… more

Monodispersed magnetic nanoparticles for improved diagnostic imaging. Phase II: S

Company: CONFLUENCE LIFE SCIENCES, LLC Agency/Program/Year/Phase: HHS / SBIR / 2013 / 1
Abstract: DESCRIPTION (provided by applicant): Pancreatic cancer (PC) is the fourth leading cause of death from cancer in the US. Treatment options for this disease are extremely limited and prognosis is poor. At present, less than 6% of PC patients are alive afterfive years with an average survival time… more

Hollow Fiber Concentrating Pipette Tip for Improved Pathogen Detection in Foods

Company: INNOVAPREP, LLC Agency/Program/Year/Phase: HHS / SBIR / 2013 / 2
Abstract: Abstract Rapid microbiological methods offer great potential for increasing the reliability of pathogen detection in foods while reducing labor costs and product hold times, however, small analysis volumes limit the usefulness of these methods. Pre-enrichment is often used to overcome this… more

Modular, Rapid, Common Hardware-in-the-loop Framework Development

Company: WideBand Corporation Agency/Program/Year/Phase: DOD / SBIR / 2012 / 2
Abstract: The Phase II technical objective of this project is to implement the technology conceived in Phase I into hardware prototypes that can be tested in an actual HWIL test lab environment. The developments and experience acquired in Phase I will be used to design and assemble a fully functional central… more

Treatment of Transplant Reperfusion with CD47 antibody

Company: VASCULOX, INC. Agency/Program/Year/Phase: HHS / SBIR / 2012 / 2
Abstract: DESCRIPTION (provided by applicant): Vasculox, Inc. is developing a humanized anti-CD47 mAb for reducing ischemia-reperfusion injury (IRI) in organ transplantation. In spite of improvements in surgical technique, organ preservation and immunosuppression, IRI remains a serious limitation and is… more

Adjunctive Use of Apyrase to Fibrinolytic Therapy

Company: APT THERAPEUTICS, INC. Agency/Program/Year/Phase: HHS / SBIR / 2012 / 2
Abstract: DESCRIPTION (provided by applicant): Acute myocardial infarction is the leading cause of death in most industrialized nations. The estimated annual incidence in the US is 865,000 events, with ST-segment elevation myocardial infarction (STEMI, severe AMI)comprising an estimated 500,000 events per… more