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SBIR Phase I: Controlled Drug Release from and Degradation of PEG-Hydrogels

Company: PROLYNX, LLC Agency/Program/Year/Phase: NSF / SBIR / 2013 / 1
Abstract: … are independently predictable, simple to control, and do not show the initial bursts of drug release or terminal drug-dumping characteristic of encapsulating systems. Commercial success will be achieved by a) partnerships where we use our technology for proprietary drugs of … more

Holographic Video Display (HVD)

Company: HOLOEYE Systems, Inc. Agency/Program/Year/Phase: DOD / SBIR / 2013 / 1
Abstract: … in standard stereo displays. In this program HSI will study and design key components of this system. As it evolves this holography development will provide new realism to displays including near to eye, multiuser monitors, and projection displays. BENEFIT: Drug creation,… more

Probiotics for Maintaining Dolphin (Tursiops truncatus) Health and the Readiness of the U.S. Navy"s Marine Mammal Systems

Company: Accacia International LLC Agency/Program/Year/Phase: DOD / STTR / 2013 / 1
Abstract: …s and detect underwater mines. The maintenance and betterment of health of these dolphins in captivity is a priority in order to improve the fitness and readiness of these animals for defense missions. Accacia International proposes to develop probiotic pharmaceuticals to treat… more

Probiotics for Maintaining Dolphin (Tursiops truncatus) Health and the Readiness of the U.S. Navy"s Marine Mammal Systems

Company: Agave BioSystems, Inc. Agency/Program/Year/Phase: DOD / STTR / 2013 / 1
Abstract: Agave BioSystems, with their academic partners at the Mote Marine Laboratory, proposes to develop probiotic pharmaceuticals from indigenous commensal microbes to enhance gastrointestinal health in the bottlenose dolphin (Tursiops truncatus). The dolphin gastrointestinal… more

New 3He Replacement Sensors for DOE Material Control and Accountability

Company: Radiation Monitoring Devices, Inc. Agency/Program/Year/Phase: DOE / SBIR / 2013 / 2
Abstract: … physics research, nuclear waste cleanup, nuclear treaty verification, geological exploration and development of new sources to effectively address our nations future energy needs. Proposed detectors will also permit scientific research enabling development of new drugs,… more

Nondestructive Evaluation of Thick Outer Mold Line Paints and Coatings

Company: ChromoLogic LLC Agency/Program/Year/Phase: DOD / SBIR / 2013 / 1
Abstract: … coatings on aircraft carriers, naval ships, and submarines. In the civilian market, CIMOSA could used to detect oxidative corrosion in coatings on commercial airplanes and automobiles, detection of false coatings on counterfeit electrical components, counterfeit drug… more

Enhanced Monomer (Isosorbide) Synthesis from Biomass (cellulose) Source

Company: Compact Membrane Systems, Inc. Agency/Program/Year/Phase: DOE / SBIR / 2013 / 1
Abstract: … in collaboration with the group of Professor Robin Rogers at the University of Alabama, will develop new technology for the acid catalyzed conversion of the plant-derived sugar sorbitol to isosorbide, a diol of interest as a chemical intermediate, pharmaceutical… more

Development of an Acoustic Instrument for Bubble Size Distribution Measurement in Mercury

Company: Dynaflow, Inc. Agency/Program/Year/Phase: DOE / SBIR / 2013 / 2
Abstract: … development of the proposed instrument will have wide commercial and scientific applications and benefits. In addition to the Spallation Neutron Source application, the instrument will find applications in oceanographic, biological, chemical, pharmaceutical, energy, and… more

Inverse Synthetic Aperture Radar (ISAR) For Terrestrial Targets

Company: Electromagnetic Systems, Inc. Agency/Program/Year/Phase: DOD / SBIR / 2013 / 2
Abstract: …ng and a game changer for automated target recognition". Air Force transition systems include Dismount Detection Radar (DDR) and other next generation Air Force ISR radar systems. Non DoD transitions opportunities exist in border security applications and drug enforcement… more

Safe and Renewable Plasticizers from Cellulose

Company: Exelus, Inc. Agency/Program/Year/Phase: DOE / SBIR / 2013 / 1
Abstract: … safe and renewable. Unfortunately, the feedstock sorbitol is produced in too small quantities and at too high of a price to be competitive with petroleum-derived phthalates. As a result of the cost, isosorbide is largely restricted to highly specialized uses in pharmaceuticals… more

Three-Dimensional Test Materials for Solid Supports

Company: Prime Synthesis Agency/Program/Year/Phase: DOC / SBIR / 2013 / 1
Abstract: …, and are well within the technical capabilities of PSI. The proposed structural studies would be of great value in developing a family of HybridCPG products that could dramatically reduce the manufacturing costs of several important classes of advanced … more

SBIR Phase I: Amphiphilic copolymers as thickening agents for personal care products

Company: ATRP Solutions, Inc. Agency/Program/Year/Phase: NSF / SBIR / 2013 / 1
Abstract: … potential of this project is the need to replace PEG-based personal care additives, driven by reports that these materials contain toxic side products left after the manufacturing process, such as 1,4-dioxane, among others. The United States Food and Drug… more

Geographically-Aware and Targeted Secure Information Dissemination (GATSID)

Company: IMAGE MATTERS Agency/Program/Year/Phase: DOD / SBIR / 2013 / 1
Abstract: … and social constraints. BENEFIT: The completion of this project will result in the creation of a secure alert dispatch system for mobile devices that can be used with confidence in adverse communications and hostile environments, including warfighting, peace-keeping, drug… more

SBIR Phase I: UV Plasma-Shell Device for Novel Photocatalytic Process

Company: Imaging Systems Technology Agency/Program/Year/Phase: NSF / SBIR / 2013 / 1
Abstract: … systems that will result from this research will help to spread access to clean water. Additional promising applications for the UV light emitting Plasma-shells include sterilization of surface areas, purification of air, medical light therapy, protein analysis, drug… more

Large Scale, Low Temperature Microplasma UV Lighting Tiles for Water Purification and Sterilization

Company: Eden Park Illumination, Inc. Agency/Program/Year/Phase: DOE / SBIR / 2013 / 2
Abstract: … ranges in a slim and flat form factor. UV light is an efficient light source for a number of chemical processes and disinfection methods available commercially. It is known to be extremely effective for neutralizing pathogens (bacteria, viruses, cysts) and drugs such… more

SBIR Phase I: Novel Polymer Brush-like Architecture for Temperature Dependent Cell Release and Attachment

Company: Innovative Surface Technologies, Inc. Agency/Program/Year/Phase: NSF / SBIR / 2013 / 1
Abstract: … simple equipment, is manufacture-friendly, cost-effective, and is available in formats needed for tissue engineering and high-throughput applications. Thus, clinical applications of cell types that were previously considered impossible may be realized, and cell therapy, drug… more

Improved Method for the Production of Tetrahydrofuran from Biomass

Company: Kse, Inc. Agency/Program/Year/Phase: DOE / SBIR / 2013 / 1
Abstract: …arge volume commodity chemical used in the production of polytetramethylene ether glycol (PTMEG), a component of polyurethane stretch fibers (Spandex) and as an industrial solvent with applications in polyvinyl chloride (PVC) cements, pharmaceuticals and… more

Small Molecule Antiviral Agents Against Flaviviruses

Company: L2 DIAGNOSTICS, LLC Agency/Program/Year/Phase: DOD / SBIR / 2013 / 2
Abstract: …, dengue viruses, and other flaviviruses. In Phase I of this project, we identified several candidate tetrapeptides able to neutralize multiple flaviviruses in in-vitro assays. These very short peptides have a molecular weight below 500, affording them the favorable drug… more

Flexible, Energy Efficient Ammonia Synthesis

Company: Lynntech, Inc. Agency/Program/Year/Phase: DOE / SBIR / 2013 / 1
Abstract: … energy source. Commercial Applications and Other Benefits Demand for ammonia in the United States continues to increase. The primary use of ammonia is as a fertilizer; but it is also needed for diverse applications such as com- mercial cleaning products, pharmaceutical… more

SBIR Phase I: Tool for cancer protein crystallization based on intrinsically disordered protein

Company: MOLECULAR KINETICS, INC. Agency/Program/Year/Phase: NSF / SBIR / 2013 / 1
Abstract: …cing crystallization. This new application of our entropic bristle technology will allow the three-dimensional structures of proteins to be determined more quickly and reliably. Knowledge of the structures of disease-related proteins is extremely valuable in designing drugs that… more

SBIR Phase I: New Fluorescent Biosensors for Signaling in Living Cells

Company: MONTANA MOLECULAR, LLC Agency/Program/Year/Phase: NSF / SBIR / 2013 / 1
Abstract: This Small Business Innovation Research (SBIR) Phase I project will establish the feasibility of developing a genetically-encoded biosensor to monitor levels of cyclic adenosine monophosphate (cAMP), an important second messenger component of drug signaling pathways. Unlike… more

The Most Efficient (TME) Cold Chain Container for Blood

Company: Resodyn Corporation Agency/Program/Year/Phase: DOD / SBIR / 2013 / 1
Abstract: Resodyn Corporation proposes to develop a novel cold chain system with a Lifetime Warranty for the vacuum container. The container composes a passive energy efficient system for transporting blood and pharmaceuticals in hostile environments for up to three days. Capacity is… more

Marking of Components for Avoidance of Counterfeit Parts

Company: NanoInk, Inc. Agency/Program/Year/Phase: DOD / SBIR / 2013 / 1
Abstract: … method for IC packages of all shapes and materials that can protect against relabeling, delidding and outright copying. The approach is a novel application of the NanoEncryption platform which has been successfully commercialized for the protection of … more

Cryogenically Flexible, Low Permeability Thoraeus Rubber H2 Dispenser Hose

Company: NanoSonic, Inc. Agency/Program/Year/Phase: DOE / SBIR / 2013 / 1
Abstract: … nanocomposites with ultra-thin (10 100 nm), uniform layers of particles that maintain EMI shielding (up to -100 dB over 4 18 GHz) upon mechanical strains up to 50 % elongation. NanoSonics partner, ILC Dover, is the leading manufacturer of flexible pharmaceutical containment… more

Characterizing the Impact of Ionospheric Wave Structures on Coordinate Registration.

Company: NorthWest Research Associates, Inc. Agency/Program/Year/Phase: DOD / SBIR / 2013 / 1
Abstract: …ed OTHR Coordinate Registration accuracy. Improved CR accuracy will enhance the applicability of OTHR as a wide area surveillance asset for Air Force and Homeland Security applications with dramatic cost savings over alternative microwave radar solutions. In the US counter … more