Development of a Hybrid Dynamic Stent
Company: CorInnova Incorporated Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1Abstract: … that are best suited to minimize wall stresses and promote re-endothelialization are least suited to retain intimal flaps and inhibit platelet aggregation. Fortunately, these concerns are most significant along different time frames post-stent deployment. CorInnova is… more
Online patient self-assessment system for care and research of joint and skin dis
Company: CPM SYSTEMS, INC. Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1Abstract: … are no practical, integrated systems for assessing biomedical,psychosocial, and behavioral (BPSB) issues--and physicians often lack the time and resources for such total care. SOLUTION: Our goal is to extend an existing online patient (pt) self-assessment system, called Care… more
Rapid intercalator removal from size-selected DNA for next generation sequencing
Company: DIFFINITY GENOMICS, INC. Agency/Program/Year/Phase: HHS / STTR / 2012 / 1Abstract: … Science introduceda disruptive product for DNA size selection that electrically switches the desired DNA fragments out of the gel and obviates the need for physically extracting the DNA. Due to its speed and labor saving protocol, the Sage Science Pippin Prep is… more
The Use of Micro-Channel Reactors for Process Intensification in the Production of Transportation Fuels from Biomass
Company: InnovaTek, Inc. Agency/Program/Year/Phase: DOE / SBIR / 2012 / 1Abstract: … Compared to cellulose and lignin, hemicelluloses are generally much less stable and are prone to degradation during chemical or thermal treatments. For this reason, hemicellulose is considered an underutilized biomass component in most biomass conversion processes. InnovaTek ,… more
Point of Care Detection of Respiratory Viruses
Company: LUCIGEN CORPORATION Agency/Program/Year/Phase: HHS / SBIR / 2012 / 2Abstract: … multiplex testing capabilities residing in a single, inexpensive device wil enable near point of care diagnostics for a number of serious infectious agents. The research design for achieving this goal includes four processing elements: 1) A one step sample prep that can be… more
Automated Large and Mid Scale Nucleic Acid Preparation
Company: MACCONNELL RESEARCH CORPORATION Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1Abstract: …cessing instrument that will purify one milligram or more of plasmid DNA from recombinant culture in 60 minutes.The purification method to be employed in this work is a derivative of proven electrophoretic separation technology that our company developed for automated mini-prep… more
Improved Resin Injection Repairs for Polymer Composite Materials
Company: Performance Polymer Solutions Inc. Agency/Program/Year/Phase: DOD / SBIR / 2012 / 1Abstract: …. Large integrated composite structures, low scrap rates, high integrity structural repair, and suitability to the manufacturing shop floor are all primary drivers for this proposed repair technology and will be enabled by our innovative combination of surface prep, repair… more
A Novel Fractionation and Concentration System for Improved Biological Detection
Company: InnovaPrep LLC Agency/Program/Year/Phase: DHS / SBIR / 2012 / 2Abstract: … and detection components requiring
very small volumes, (b) deficiencies in removing inhibitory environmental material and (c) an inability to separate, and thus, differentiate whole
pathogens from exogenous materials derived from those pathogens. InnovaPrep is… more
Universal Bio-Sample Preparation Module
Company: Physical Optics Corporation Agency/Program/Year/Phase: DOD / SBIR / 2012 / 2Abstract: …, CBD is seeking a platform technology for automated, universal sample preparation for biosensor systems using small volumes of samples in complex matrices. To address this need, Physical Optics Corporation (POC) proposes to develop a Universal Bio-sample Preparation (UniBio… more
Deployable Pan-flavivirus and Pan-alphavirus Assays for Screening Pools of Medically Relevant Arthropod
Company: CUSTOMARRAY, INC. Agency/Program/Year/Phase: DOD / SBIR / 2012 / 2Abstract: … this prototype detection assay as a launching pad for developing the instrumentation necessary to automate the assay and create a truly field-deployable system. In this proposal, we outline our strategy for this automation. We will (1) automate the sample prep system to… more
SBIR Phase II: Efficient Manufacturing of Nanostructured Flexible Transparent Conducting Electrodes
Company: Innova Dynamics Agency/Program/Year/Phase: NSF / SBIR / 2012 / 2Abstract: This Small Business Innovation Research (SBIR) Phase II project aims to develop high-performance transparent conductors as a replacement to Indium Tin Oxide (ITO) in touchscreens. ITO suffers from a number of disadvantages, including being one of the most expensive components of a touchscreen device… more
Electrically conductive aircraft transparency materials via Innlay surface-embedding
Company: Innova Dynamics Agency/Program/Year/Phase: DOD / SBIR / 2012 / 2Abstract: This Small Business Innovation Research (SBIR) Phase II project proposal to the U.S. Department of Defense, NAVAIR, Navy, outlines the plan for the qualification of robust, non-delaminating, highly conductive aircraft transparency materials using the Innlay (TM) surface-embedding technology platform… more
Practical Non-contact ECG Electrodes for Prep-free Monitoring
Company: Cognionics Agency/Program/Year/Phase: NASA / SBIR / 2012 / 1Abstract: Cognionics has developed a high-quality, low-noise, dry/non-contact ECG electrode that can obtain signals even through layers of clothing without any skin preparation. Although the idea of a non-contact electrode is not new and has been previously investigated by other research groups, a successful… more
Integrated system for preparation of NGS libraries from crude biological samples
Company: SAGE SCIENCE, INC. Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1Abstract: … to microfluidic sample preparation. A single continuous-flow technology is used to manipulate and separate cells, subcellular organelles, and large genomicDNA molecules (that exhibit particle-like properties). The use of a common technology for all sample prep steps… more
Interactive Multimedia Intervention to Improve Colonoscopy and Bowel Prep Adhere
Company: QURVE LEARNING, LLC Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1Abstract: DESCRIPTION (provided by applicant): Mortality from colorectal cancer (CRC) can be reduced through screening programs. Regardless of the primary strategy (fecal occult blood testing, sigmoidoscopy, colonoscopy, fecal DNA, computed tomographic colonography[virtual colonoscopy]) colonoscopy is… more
SBIR Phase I: Efficient manufacturing of nanostructured flexible transparent conducting electrodes
Company: Innova Materials Agency/Program/Year/Phase: NSF / SBIR / 2011 / 1Abstract: This Small Business Innovation Research (SBIR) Phase I project aims to develop efficient manufacturing of nanostructured flexible transparent conducting electrodes (TCEs) with low resistivity and high durability. Flexible nanostructured TCEs will be produced by using the proprietary… more
Electrically conductive aircraft transparency materials via Innlay surface-embedding
Company: Innova Materials Agency/Program/Year/Phase: DOD / SBIR / 2011 / 1Abstract: This Small Business Innovation Research (SBIR) Phase I project proposal to the U.S. Department of Defense (DoD), Navy, requests funding for Innova Dynamics, Inc. to enable innovative manufacturing of robust, non-delaminating, highly conductive aircraft transparency materials… more
Improved Landing Gear Grinding/Finishing Methods on Hard Wear Resistant Surfaces
Company: (ES3) ENGINEERING & SOFTWARE SYSTEM SOLUTION, INC. Agency/Program/Year/Phase: DOD / SBIR / 2011 / 2Abstract: …ently replacing chrome plating with High Velocity Oxygenated Fuel (HVOF) applied tungsten carbide-cobalt (WC-Co and WC-Co-Cr) coatings. These coatings require diamond wheels for finish grinding the HVOF coatings as well as aluminum oxide grinding wheels for base metal prep and… more
BioPrep: A Novel Microfluidic Cartridge for Universal Bio-sample Preparation
Company: CFD Research Corporation Agency/Program/Year/Phase: DOD / SBIR / 2011 / 1Abstract: … a host of detection moieties (e.g., DNA, RNA, proteins, peptides, whole cells). Ideally, a fieldable bio-sample preparation platform should be rapid, compact, reagent-less, automated, require minimal user training, and universal. We propose to develop a general purpose Bio… more
Online patient self-assessment for chronic pancreatic and other pain
Company: CPM SYSTEMS, INC. Agency/Program/Year/Phase: HHS / SBIR / 2011 / 1Abstract: … CPP through apinhole. SOLUTION: Our objective is to develop an assessment for the biomedical, psychosocial, behavioral, and quality-of-life (biopsychosocial, BPS) dimensions of CPP for an existing online, branching, patient self- assessment system called CarePrep, thereby… more
Integrated Online Assessment and Intervention Targeting Health Disparities
Company: CPM SYSTEMS, INC. Agency/Program/Year/Phase: HHS / SBIR / 2011 / 1Abstract: … prevalent than preventive care. SOLUTION: Our objective is to deploy a clinical methodology and infrastructure to ensure delivery of patient-centered care to minority and disadvantaged patients. Our work builds on an online, patient self-assessment system called CarePrep, now… more
Web-based Biopsychosocial Assessment and Intervention for Alcohol Misuse
Company: CPM SYSTEMS, INC. Agency/Program/Year/Phase: HHS / SBIR / 2011 / 1Abstract: … the chart. If you want to know about AMU, patients must be asked directly; providers will not know and paper questionnaires cannot be scaled into an effective solution. SOLUTION: Our work builds on an operational, Web-based, patient self-assessment system called CarePrep that… more
Fuel Cell Range Extender for Battery-Powered Airport Ground Support Equipment
Company: InnovaTek, Inc. Agency/Program/Year/Phase: DOE / SBIR / 2011 / 1Abstract: …tended range through integration with a fuel cell that operates on renewable liquid hydrocarbon fuel will meet the needs of airlines and ground handling companies to reduce emissions and fuel costs and provide the convenience of a standard liquid refueling operation. InnovaTek… more
CATALYTIC MEMBRANE REACTOR FOR THE PRODUCTION OF HYDROGEN FROM BUTANOL
Company: InnovaTek, Inc. Agency/Program/Year/Phase: DOD / STTR / 2011 / 2Abstract: A compact and efficient fuel processor that provides clean hydrogen from a high energy density liquid fuel such as butanol will allow fuel cell technology to be realized in military and commercial markets for portable applications. InnovaTek, and its proposal partner Indiana -… more
Rapid Concentration and Detection of E. Coli in Liquid Samples
Company: InnovaPrep LLC Agency/Program/Year/Phase: HHS / SBIR / 2011 / 1Abstract: … bacteria fromreal apple juice and spinach wash water into a small volume, which is easily analyzed by advanced detectors, will enable rapid detection of small numbers of bacteria; and, in turn will provide for improved consumer safety and reduced product recalls. InnovaPrep… more