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Agency:HHS
Year:2011
Phase:Phase I
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Displaying 76 – 100 of 782 Awards
Company: AGILTRON, INC. Agency/Program/Year/Phase: HHS / SBIR / 2011 / 1
Abstract: DESCRIPTION (provided by applicant): The overall goal of this proposed research is to adopt an inexpensive IR camera and image analysis software for non-contact monitoring the breath of a premature infant. Sleep apnea in these patients can lead to significant health problems, even death. Existing… more
Company: AGILTRON, INC. Agency/Program/Year/Phase: HHS / SBIR / 2011 / 1
Abstract: Agiltron proposes to develop volumetric optical coherence microscopic imaging technology for the full anterior chamber of the rabbit eye with high depth resolution, high speed, and high sensitivity to quantitatively assess the depth and extent of initial injury (001) in ocular irritant test. Studies… more
Company: AKINA, INC. Agency/Program/Year/Phase: HHS / SBIR / 2011 / 1
Abstract: DESCRIPTION (provided by applicant): The objective of this Phase I study is to develop an intra-oral, adhesive film which can cover and protect various mouth sores and deliver low doses of pain relieving lidocaine and anti-inflammatory doxycycline to thesore site. In particular, we will focus on… more
Company: AKONNI BIOSYSTEMS, INC. Agency/Program/Year/Phase: HHS / SBIR / 2011 / 1
Abstract: DESCRIPTION (provided by applicant): ABSTRACT Aseptic encephalitis and meningitis are potentially fatal diseases defined by acute swelling of the brain or protective membranes covering the brain and spinal cord. These diseases can be caused by viruses,bacteria, fungi and parasites. Viruses are… more
Company: 21ST CENTURY THERAPEUTICS, INC. Agency/Program/Year/Phase: HHS / SBIR / 2011 / 1
Abstract: Radiotherapy can potentially inflict serious damage on healthy normal organs. For example, pneumonitis and fibrosis are two well-recognized adverse effects from lung cancer radiotherapy: Currently, amifostine (Ethyol) is the only approved radioprotector indicated to reduce xerostomia associated with… more
Company: Radiation Monitoring Devices, Inc. Agency/Program/Year/Phase: HHS / SBIR / 2011 / 1
Abstract: DESCRIPTION (provided by applicant): This proposal's main objective is the development of a novel Perfusion Monitoring Device (PMD) based upon diffuse correlation spectroscopy (DCS), which will enable microsurgeons to assess the level of vascularization ofburied (prelaminated) flaps and the… more
Company: Radiation Monitoring Devices, Inc. Agency/Program/Year/Phase: HHS / SBIR / 2011 / 1
Abstract: DESCRIPTION (provided by applicant): The onset of hemorrhagic shock is a major cause of death in emergency departments and trauma centers. Currently there is no clinically accepted quantitative monitor of the onset of hemorrhagic shock. Death from hemorrhagic shock results from diminished capillary… more
Company: Radiation Monitoring Devices, Inc. Agency/Program/Year/Phase: HHS / SBIR / 2011 / 1
Abstract: DESCRIPTION (provided by applicant): Positron Emission Tomography (PET) is a functional imaging technique with the potential to quantify the rates of biological processes in vivo. The availability of short-lived positron-emitting isotopes of carbon, nitrogen, oxygen and especially fluorine allows… more
Company: ALLTRANZ, INC. Agency/Program/Year/Phase: HHS / SBIR / 2011 / 1
Abstract: DESCRIPTION (provided by applicant): With over 8.5% of the U.S. population and 75 million people worldwide meeting the diagnostic criteria for alcohol use disorders (AUDs), alcohol abuse is among the top three preventable public health problems in the U.S.and the world. AUDs, commonly referred to as… more
Company: VASCULOX, INC. Agency/Program/Year/Phase: HHS / SBIR / 2011 / 1
Abstract: DESCRIPTION (provided by applicant): Organ transplantation is one of the great success stories of modern medicine. However, the supply of suitable organs lags far behind the need and many patients die while waitlisted for organs. While there have been manyrecent strides in organ procurement,… more
Company: AM BIOTECHNOLOGIES, LLC Agency/Program/Year/Phase: HHS / SBIR / 2011 / 1
Abstract: DESCRIPTION (provided by applicant): Functional RNA molecules such as aptamers, siRNAs, miRNAs, and related compounds have enormous potential as human therapeutics and as tools for elucidating gene regulation in vivo. To reach this potential, such molecules must be highly potent and highly nuclease… more
Company: AMBERGEN, INC Agency/Program/Year/Phase: HHS / SBIR / 2011 / 1
Abstract: DESCRIPTION (provided by applicant): Sequencing of the human genome has led to a new and even more ambitious goal - characterization of the human proteome. Such an endeavor involves not only understanding the function of hundreds of thousands of differentproteins expressed in human cells but also… more
Company: AMERICAN STEM CELL, INC. Agency/Program/Year/Phase: HHS / SBIR / 2011 / 1
Abstract: DESCRIPTION (provided by applicant): Three primary sources of hematopoietic stem cells (HSCs) are routinely used in HSC therapy. These include mobilized peripheral blood, bone marrow and umbilical cord. While each source has its individual benefits, cord blood has seen increased usage over the past… more
Company: AMERICAN STEM CELL, INC. Agency/Program/Year/Phase: HHS / SBIR / 2011 / 1
Abstract: DESCRIPTION (provided by applicant): The three primary sources of hematopoietic stem cells (HSCs) for bone marrow transplant are: mobilized peripheral blood, bone marrow, and umbilical cord. While each source has its individual benefits and limitations, cord blood has seen increased usage over the… more
Company: AMRON CORPORATION Agency/Program/Year/Phase: HHS / SBIR / 2011 / 1
Abstract: DESCRIPTION (provided by applicant): The research proposed here will show the feasibility of an electronic method to measure and report hand hygiene compliance, called Monitor for Hand Hygiene on Patient Contact (MHHPC). MHHPC will determine, record and report whether anyone touching a hospital… more
Company: ANGION BIOMEDICA CORPORATION Agency/Program/Year/Phase: HHS / SBIR / 2011 / 1
Abstract: DESCRIPTION (provided by applicant): Alcoholic and non-alcoholic liver fibrosis remains an unsolved challenge for the hepatologist as it can lead to cirrhosis and end-stage liver disease, a life-threatening condition that necessitates liver transplantation. Current therapeutic strategies for the… more
Company: APHIOS CORPORATION Agency/Program/Year/Phase: HHS / SBIR / 2011 / 1
Abstract: This Phase I, SBIR contract is to conduct a thorough biological and phytochemical analysis of Harpagophytum procumbens. This should result in discovery of new biologically active molecules and/or a more comprehensive understanding of the contributions madeby the known constituents.
Company: APHIOS CORPORATION Agency/Program/Year/Phase: HHS / SBIR / 2011 / 1
Abstract: The contractor will identify methodologies for broad spectrum inactivation of pathogens in red blood cell concentrates(RBCC). RBCCs are the main components of blood used in transfusion medicine, yet currently there are no FDAapproved methods for broad spectrum pathogen inactivation for RBCCs;… more
Company: APPLIED BEHAVIORAL RESEARCH, LLC Agency/Program/Year/Phase: HHS / SBIR / 2011 / 1
Abstract: DESCRIPTION (provided by applicant): Our recent series of innovative randomized trials evaluating the efficacy of various strategies for training clinicians to use evidence based therapies in alcohol and drug abuse has indicated that while both in-personworkshop and computer-assisted training can… more
Company: ARAVASC, INC. Agency/Program/Year/Phase: HHS / SBIR / 2011 / 1
Abstract: Esophageal cancer is a deadly disease with limited treatment options. In addition to modest effects, toxic chemo-therapy drugs cripple patients with debilitating side-effects. This proposal utilizes an Esophageal Theranostic Delivery System (ETDS), to address this clinical need with a multi-modal… more
Company: ARMAGEN TECHNOLOGIES, INC. Agency/Program/Year/Phase: HHS / SBIR / 2011 / 1
Abstract: DESCRIPTION (provided by applicant): Type II Mucopolysaccharidosis (MPS), also known as Hunter's syndrome, is an genetic disease that affects the lysosomal enzyme, iduronate-2-sulfatase (IDS). Consequently, patients with MPS-II develop extensive lysosomalstorage product accumulation in tissues… more
Company: ARMAGEN TECHNOLOGIES, INC. Agency/Program/Year/Phase: HHS / SBIR / 2011 / 1
Abstract: DESCRIPTION (provided by applicant): Erythropoietin (EPO) is a potential new pharmaceutical to treat vascular disease of the brain, including stroke. However, EPO is a large molecule pharmaceutical that does not cross the capillary endothelial wall in brain, which forms the blood-brain barrier (BBB)… more
Company: ARTERIOCYTE, INC. Agency/Program/Year/Phase: HHS / SBIR / 2011 / 1
Abstract: DESCRIPTION (provided by applicant): Malaria results from infection by one of five species of mosquito-borne parasite. Each year, these protists infect 350-500 million worldwide and kill over one million people. Over three billion people living in tropicalregions are exposed to malaria every year.… more
Company: ARTIFICIAL CELL TECHNOLOGIES, INC. Agency/Program/Year/Phase: HHS / SBIR / 2011 / 1
Abstract: DESCRIPTION (provided by applicant): Respiratory syncytial virus (RSV) is the most important cause of severe lower respiratory tract illness in infants and the elderly. There is no approved vaccine despite decades of effort. Early attempts to develop a formalin- inactivated vaccine (FI-RSV) resulted… more
Company: Ashwin-Ushas Corporation, Inc. Agency/Program/Year/Phase: HHS / SBIR / 2011 / 1
Abstract: DESCRIPTION (provided by applicant): Age-Related Macular Degeneration (ARMD) afflicts up to 40% of the aging population [1-30]. Studies [6-30] show that gt 70% of the visually impaired population in the US is over 60, and within this, ARMD is the largest cause of impairment. A primary characteristic… more
Displaying 76 – 100 of 782 Awards
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