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Phase:Phase I
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Displaying 21826 – 21850 of 22474 Awards
Company: GENESIS LABORATORIES, INC Agency/Program/Year/Phase: HHS / SBIR / 1985 / 1
Abstract: N/A
Company: GENESIS LABORATORIES, INC Agency/Program/Year/Phase: HHS / SBIR / 1985 / 1
Abstract: N/A
Company: Genesys Research, Inc. Agency/Program/Year/Phase: HHS / SBIR / 1985 / 1
Abstract: HAMSTER OVARY CELLS IN RESPONSE TO PRESENT CONCERNS REGARDING THE EFFICACY OF THE L5178Y MOUSE LYMPHOMA CELL MUTAGENESIS ASSAY (MLA) AT THE TK LOCUS, THERE ARE NEEDS TO EXAMINE FURTHER THE HYPOTHESIS THAT THE PRESENCE OF SMALL MOUSE LYMPHOMA COLONIES IN A BIMODAL DISTRIBUTION OF COLONY SIZES IS… more
Company: Genesys Research, Inc. Agency/Program/Year/Phase: HHS / SBIR / 1985 / 1
Abstract: IN RESPONSE TO PRESENT CONCERNS REGARDING THE EFFICACY OF THE L5178Y MOUSE LYMPHOMA CELL MUTAGENESIS ASSAY (MLA) AT THE TK LOCUS, THERE ARE NEEDS TO DETERMINE WHETHER VARIABILITY IN MUTATION FREQUENCY RATIOS BETWEEN EXPERIMENTS IS COMPOUND SPECIFIC OR THE RESULT OF VARIABILITY IN TESTING CONDITIONS… more
Company: Genetic Diagnostics Corp Agency/Program/Year/Phase: HHS / SBIR / 1985 / 1
Abstract: RECENT STUDIES IN MANY LABORATORIES HAVE DEMONSTRATED THE PRESENCE OF 2 UBIQUITOUS, CLOSELY RELATED ENZYMES, THE CALCIUM-ACTIVATED PROTEASES (CAP I AND II). IN BRAIN, THE CAP ENZYMES ACT ON NEUROFILAMENT PROTEINS AND LEAD TO THE DEGRADATION OF THESE NEURONAL COMPONENTS. THE NEUROFILAMENT PROTEINS… more
Company: Genetics Data Services Inc. Agency/Program/Year/Phase: HHS / SBIR / 1985 / 1
Abstract: N/A
Company: GENTEST CORPORATION Agency/Program/Year/Phase: HHS / SBIR / 1985 / 1
Abstract: N/A
Company: Gentronix Laboratories, Inc. Agency/Program/Year/Phase: HHS / SBIR / 1985 / 1
Abstract: A MERGER OF TECHNOLOGIES INVOLVING POLYMER FIBER OPTICS, POLYMER PHTHALOCYANINE PHOTO VOLTAICS AND ELECTRODE CELL ADHESION SURFACES HAS RESULTED IN THE CONCEPT OF A NOVEL SENSORY PROSTHESIS WHICH USES FINE (510) POLYMER OPTICAL FIBERS INSTEAD OF METAL WIRES. USING A PHOTO CONVERSION MECHANISM AT… more
Company: Genzyme Corp. Agency/Program/Year/Phase: HHS / SBIR / 1985 / 1
Abstract: HETEROANTISERA AGAINST INTERFERON (IFN) AND INTERLEUKIN-2 (IL-2) ARE HIGHLY IMMUNOSUPPRESSIVE WHEN INJECTED INTO EXPERIMENTAL ANIMALS. THESE ANTICYTOKINES IMPAIR THE GENERATION OF CYTOLYTIC T CELLS, THE REJECTION OF TRANSPLANTED TUMORS, AND OTHER CELLULAR IMMUNE FUNCTIONS. MURINE MONOCLONAL… more
Company: Giner, Inc. Agency/Program/Year/Phase: HHS / SBIR / 1985 / 1
Abstract: N/A
Company: Good Health Communications Agency/Program/Year/Phase: HHS / SBIR / 1985 / 1
Abstract: CAREGIVERS OF DEMENTED ELDERLY PERSONS EXPERIENCE A HIGH DEGREE OF STRESS. VIDEO PROGRAMS THAT TEACH RELAXATION AND MOTIVATE PRACTICE AND APPLICATION MAY BE A VIABLE, COST-EFFECTIVE WAY TO SUPPORT AND ENHANCE CAREGIVERS' HEALTH AND EFFICACY. IN PHASE I, SUBJECTS (SS) ARE PRIMARY CAREGIVERS OF… more
Company: Granite Diagnostics Agency/Program/Year/Phase: HHS / SBIR / 1985 / 1
Abstract: COLORECTAL CARCINOMA IS ONE OF THE MOST PREVALENT AND LETHAL CANCERS IN THE UNITED STATES. ACCORDING TO THE AMERICAN CANCER SOCIETY, THERE ARE 130,000 NEW CASES EACH YEAR. EARLY DIAGNOSIS IS DIFFICULT AND THERE IS NO DIAGNOSTIC TEST WITH A HIGH POSITIVE PREDICTIVE VALUE IN THE EARLY STAGES OF THE… more
Company: Greenmark Inc Agency/Program/Year/Phase: HHS / SBIR / 1985 / 1
Abstract: TECHNOLOGY DEVELOPED ABROAD HAS INDICATED THE FEASIBILITY OF PREPARING DENTAL CASTINGS OF TITANIUM AND TITANIUM ALLOYS BY BOTH ELECTRIC ARC AND VERTICAL CENTRIFUGAL CASTING IN AN ARGON ENVIRONMENT. WE PROPOSE TO EVALUATE THE FEASIBILITY OF THESE CASTING TECHNIQUES TO FABRICATE PARTIAL DENTURE… more
Company: H. G. Pars Pharmaceutical Labo Agency/Program/Year/Phase: HHS / SBIR / 1985 / 1
Abstract: H. G. PARS PHARMACEUTICAL LABORATORIES' LONG-TERM GOAL IS TO DEVELOP AND MARKET AN ORALLY ACTIVE ANTIHYPERTENSIVE DRUG FROM ITS SERIES OF SULFUR AND NITROGEN CANNABINOID ANALOGS. HYPOTENSIVE CANNABINOIDS ARE BELIEVED TO EXERT THEIR EFFECTS BY ALTERING CENTRAL SYMPATHETIC NERVOUS SYSTEM ACTIVITY BUT… more
Company: H. G. Pars Pharmaceutical Labo Agency/Program/Year/Phase: HHS / SBIR / 1985 / 1
Abstract: THE MODIFICATION OF -LACTAM ANTIBIOTICS CONTINUES TO BE A PROMISING MEANS FOR THE IMPROVEMENT OF THIS VERY IMPORTANT CLASS OF ANTIMICROBIALS. THE VARIED USEFUL ATTRIBUTES OF THE NEW OXACEPHALOSPORIN MOXALACTAM, NAMELY BROAD SPECTRUM OF ACTIVITY, FAVORABLE PHARMACOKINETIC PROFILE, AND STABILITY,… more
Company: H. G. Pars Pharmaceutical Labo Agency/Program/Year/Phase: HHS / SBIR / 1985 / 1
Abstract: CURRENT BACTERIOCIDAL AND FUNGICIDAL AGENTS ARE UNSATISFACTORY FOR USE ON SENSITIVE SOFT TISSUE OR MUCOUS MEMBRANE. THERE IS NO KNOWN CHEMICAL AGENT WHICH POSSESSES BROAD-RANGE BACTERIOCIDAL AND FUNGICIDAL ACTIVITY AND IS NONIRRITANT TOWARDS OCULAR TISSUE. THE DISCOVERY OF SUCH AN AGENT WOULD BE… more
Company: H. G. Pars Pharmaceutical Labo Agency/Program/Year/Phase: HHS / SBIR / 1985 / 1
Abstract: AN EFFECTIVE ORAL MALE ANTIFERTILITY AGENT, WHICH IS BOTH NONTOXIC AND REVERSIBLE, IS NOT CURRENTLY AVAILABLE. GOSSYPOL, THE MOST PROMISING NONSTEROIDAL MALE ANTIFERTILITY LEAD, HAS AN UNACCEPTABLY NARROW THERAPEUTIC RATIO. WE PROPOSE THAT THE THERAPEUTIC RATIO MAY BE IMPROVED BY ALTERATION OF THE… more
Company: Hampshire Instruments, Inc. Agency/Program/Year/Phase: HHS / SBIR / 1985 / 1
Abstract: UNDERSTANDING THREE-DIMENSIONAL STRUCTURAL RELATIONSHIPS IN CELLS AND TISSUES IS IMPORTANT IN BOTH BASIC MEDICAL SCIENCE AND CLINICAL PATHOLOGY DIAGNOSIS. TO HELP ADDRESS THIS NEED, HAMPSHIRE INSTRUMENTS IS DEVELOPING A HIGH-RESOLUTION THREE-DIMENSIONAL OPTICAL MICROSCOPY WORKSTATION WITH… more
Company: Handicapped Childrens Technolo Agency/Program/Year/Phase: HHS / SBIR / 1985 / 1
Abstract: A STUDY IS PROPOSED WHICH WILL DETERMINE THE FEASIBILITY OF DEVELOPING A COMPUTER BASED MODEL FOR ADMINISTERING ASSESSMENT AND THERAPY TO MENTALLY RETARDED/DEVELOPMENTALLY DISABLED INFANTS AND CHILDREN. THE PRINCIPAL AIM OF PHASE I IS TO SURVEY CURRENT TECHNOLOGIES AS THEY RELATE TO THERAPY AND… more
Company: HAWAII BIOTECH, INC. Agency/Program/Year/Phase: HHS / SBIR / 1985 / 1
Abstract: THE OBJECTIVE OF THIS PROJECT IS TO USE IMMUNOLOGICAL METHODS TO PURIFY AND CHARACTERIZE THE 50 KDA ANOREXIGEN ISOLATED PREVIOUSLY IN LOW YIELDS USING CONVENTIONAL PROCEDURES. A SMALL AMOUNT OF THE PURIFIED ANOREXIGEN IS PRESENTLY AVAILABLE AND WILL BE USED TO GENERATE A SET OF MONOCLONAL ANTIBODIES… more
Company: Hem Research, Inc. Agency/Program/Year/Phase: HHS / SBIR / 1985 / 1
Abstract: THE GOAL OF THIS RESEARCH PROJECT IS TO DEVELOP A NUCLEIC ACID HYBRIDIZATION ASSAY FOR HTLV-III/LAV VIRAL DNA AND MRNA WHICH CAN BE COMPLETED WITHIN TWO HOURS, HAS MINIMAL BIOHAZARD ASSOCIATED WITH PERFORMING THE TEST, AND IS APPROPRIATE FOR AUTOMATION. THE PROBE ASSAY WILL BE TESTED FOR SENSITIVITY… more
Company: Hepar Industries, Inc. Agency/Program/Year/Phase: HHS / SBIR / 1985 / 1
Abstract: CURRENTLY THERE IS NO EFFECTIVE ORAL PROPHYLACTIC FOR THROMBOEMBOLIC DISORDERS. AS A RESULT, AFFLICTED INDIVIDUALS MUST RECEIVE SINGLE OR MULTIPLE INJECTIONS OF MEDICATION EACH DAY. THE EFFECTIVENESS OF HEPARIN AS AN ANTICOAGULANT IS WELL KNOWN. HOWEVER, HEPARIN MUST BE ADMINISTERED BY INJECTION.… more
Company: Hi-mag Inc Agency/Program/Year/Phase: HHS / SBIR / 1985 / 1
Abstract: N/A
Company: Hipple Cancer Research Agency/Program/Year/Phase: HHS / SBIR / 1985 / 1
Abstract: N/A
Company: Hipple Cancer Research Agency/Program/Year/Phase: HHS / SBIR / 1985 / 1
Abstract: N/A
Displaying 21826 – 21850 of 22474 Awards
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