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Agency:HHS
Phase:Phase I
Program:STTR
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Displaying 26 – 50 of 1573 Awards
Company: PHOENICIA BIOSCIENCES, INC. Agency/Program/Year/Phase: HHS / STTR / 2013 / 1
Abstract: DESCRIPTION (provided by applicant): Chronic refractory, or non-healing, wounds or ulcerations of the extremities represent a major medical condition affecting millions of patients. A chronic wound is defined as a wound that does not show signs of significant healing, or progresses, after use of… more
Company: INTEGRATED BIOTHERAPEUTICS, INC. Agency/Program/Year/Phase: HHS / STTR / 2013 / 1
Abstract: DESCRIPTION (provided by applicant): Up to 170 million people worldwide are chronically infected with HCV Hepatitis C virus (HCV) putting the infected individuals at significant risk for cirrhosis, liver failure and liver cancer. End- stage liver diseasecaused by HCV is the leading indication of… more
Company: KINETIC CERAMICS, INC. Agency/Program/Year/Phase: HHS / STTR / 2013 / 1
Abstract: DESCRIPTION (provided by applicant): Congenital cardiovascular defects, specifically single ventricle abnormalities, constitute the most common cause of death among infants born with birth defects. Even after surgically rerouting the single ventricle circulation via the Fontan procedure, the… more
Company: Kitware Inc. Agency/Program/Year/Phase: HHS / STTR / 2013 / 1
Abstract: DESCRIPTION (provided by applicant): Image-based evaluation of pathologies over time is complicated by variability in image acquisition and patient positioning, deformations due to respiratory and cardiac motion, and the clinical standard in radiology of comparing unaligned images. This application… more
Company: Kitware Inc. Agency/Program/Year/Phase: HHS / STTR / 2013 / 1
Abstract: DESCRIPTION (provided by applicant): Nearly 1.7 million Americans suffer traumatic brain injury (TBI) annually, which constitutes an important and significant US medical health concern. Although neuroimaging plays an important role in pathology localization and surgical planning, TBI clinical care… more
Company: NEW ENGLAND BIOLABS, INC. Agency/Program/Year/Phase: HHS / STTR / 2013 / 1
Abstract: DESCRIPTION (provided by applicant): Type II restriction enzymes (REases) are indispensible tools of modern medical research. It has long been a goal of REase manufacturers to be able to offer programmable specificity enzymes, where the sequence recognizedand resulting cutting activity can be… more
Company: PARABON COMPUTATION, INC. Agency/Program/Year/Phase: HHS / STTR / 2013 / 1
Abstract: DESCRIPTION (provided by applicant): PUBLIC HEALTH RELEVANCE PUBLIC HEALTH RELEVANCE:
Company: POLARIS HEALTH DIRECTIONS, INC. Agency/Program/Year/Phase: HHS / STTR / 2013 / 1
Abstract: DESCRIPTION (provided by applicant): The Institute of Medicine (IOM) strongly recommends that all breast cancer patients who are ending active treatment have a survivorship plan. Such a plan should assist patients in moving back to their primary care physician (PCP), provide advice for reducing… more
Company: POLARIS HEALTH DIRECTIONS, INC. Agency/Program/Year/Phase: HHS / STTR / 2013 / 1
Abstract: DESCRIPTION (provided by applicant): Management of Type 1 diabetes requires vigilant monitoring by patients who often encounter numerous barriers that can impede proper management. Barriers can include educational, psychosocial, and support issues. PolarisHealth Directions, a small business, and… more
Company: PRISM CLINICAL IMAGING INC. Agency/Program/Year/Phase: HHS / STTR / 2013 / 1
Abstract: DESCRIPTION (provided by applicant): The goal of this project is to develop functional magnetic resonance imaging (fMRI) tools to assist the diagnosis and treatment of human patients with a brain tumor or other operable pathology. The specific focus of this proposal is to produce a practical,… more
Company: PRISM CLINICAL IMAGING INC. Agency/Program/Year/Phase: HHS / STTR / 2013 / 1
Abstract: DESCRIPTION (provided by applicant): The diagnosis and treatment of patients with brain tumors and other diseases is often critically dependent on functional neuroimaging (e.g. fMRI) to identify healthy brain tissue that must be avoided during invasive surgery or radiation treatment. But,… more
Company: RADIANT CREATIVE GROUP, LLC Agency/Program/Year/Phase: HHS / STTR / 2013 / 1
Abstract: DESCRIPTION (provided by applicant): Mobile phone technology offers a variety of opportunities for innovative approaches to health communication and intervention. These opportunities have been amplified by the emergence of next-generation smartphone devices that are capable of rich multimedia and… more
Company: TRANSGENOMIC, INC. Agency/Program/Year/Phase: HHS / STTR / 2013 / 1
Abstract: DESCRIPTION (provided by applicant): Cancers develop from the life-long accumulation of critical somatic mutations due to DNA-damaging agents that lead to cells transforming into tumor-forming cells. These low-level tumor-associated somatic DNA mutations can have profound implications for… more
Company: VALA SCIENCES, INC. Agency/Program/Year/Phase: HHS / STTR / 2013 / 1
Abstract: DESCRIPTION (provided by applicant): The proposed project is a Phase I STTR collaboration between Vala Sciences Inc, a small business that specializes in the development of cell-based high content/high throughput assays, and the Sanford Burnham Medical Research Institute, a worldwide leader in… more
Company: VIROGENICS, INC. Agency/Program/Year/Phase: HHS / STTR / 2013 / 1
Abstract: DESCRIPTION (provided by applicant): An increasing variety of diseases are being shown to be due to immunological processes, including diabetes, and now Alzheimer's disease (AD). AD is the most prevalent age-associated disease and growing evidence suggeststhat aspects of the innate immune… more
Company: ZEN-BIO, INC. Agency/Program/Year/Phase: HHS / STTR / 2013 / 1
Abstract: DESCRIPTION (provided by applicant): Characterization of human tumor samples and cell lines in combination with inhibitor studies in animal models has established a central role for the Hh pathway in a vast array of cancer types, including small-cell lung, pancreatic, oesophageal, prostate, breast,… more
Company: PLX PHARMA, INC. Agency/Program/Year/Phase: HHS / STTR / 2013 / 1
Abstract: DESCRIPTION (provided by applicant): Colorectal cancer is the third leading cause of cancer-related deaths in the U.S. Based on numerous epidemiological studies and recent prospective trials; the use of daily aspirin is associated with a significant reduction in colorectl cancer incidence, deaths… more
Company: CELLDEX THERAPEUTICS, INC. Agency/Program/Year/Phase: HHS / STTR / 2013 / 1
Abstract: DESCRIPTION (provided by applicant): The overarching goal of this proposal is to evaluate a novel method to mobilize and procure a hematopoietic stem cell (HSC) allograft which we hypothesize will lead to rapid hematopoietic engraftment but cause less graft versus host disease (GVHD) compared to… more
Company: VIDASYM, INC. Agency/Program/Year/Phase: HHS / STTR / 2013 / 1
Abstract: DESCRIPTION (provided by applicant): Inflammatory bowel diseases (IBD) involve chronic inflammation of all or part of the digestive tract. Symptoms may include abdominal pain, severe diarrhea and malnutrition. IBD primarily includes ulcerative colitis (UC)and Crohn's disease (CD). In the West,… more
Company: COLLABORATIVE DRUG DISCOVERY, INC. Agency/Program/Year/Phase: HHS / STTR / 2013 / 1
Abstract: DESCRIPTION (provided by applicant): Identification and Validation of Targets of Phenotypic High Throughput Screening Hits for Chagas Disease Project Summary Nearly 10 million people in Latin America are infected with the eukaryotic parasite Trypanosoma cruzi, the causative agent of Chagas disease.… more
Company: ARCADIA BIOSCIENCES, INC. Agency/Program/Year/Phase: HHS / STTR / 2013 / 1
Abstract: DESCRIPTION (provided by applicant): Celiac disease (CD) is the most common food sensitive enteropathy known, affecting approximately 1% of the population and its incidence appears to be on the rise. In addition, non-celiac gluten sensitivity (GS) has recently been revealed to be a distinct… more
Company: Immuno-Mycologics INC Agency/Program/Year/Phase: HHS / STTR / 2013 / 1
Abstract: DESCRIPTION (provided by applicant): Early diagnosis of infectious disease is critical to patient outcome. An important early question is - is it a fungus, a bacterium or a virus? A rapid answer to this question would allow preemptive treatment that cansave lives. The goal of this project is a… more
Company: ARISAPH PHARMACEUTICALS, INC. Agency/Program/Year/Phase: HHS / STTR / 2013 / 1
Abstract: DESCRIPTION (provided by applicant): In the United States, around 76,250 new cases of melanoma and 9,180 melanoma-related deaths are predicted for 2012. With the therapeutic options currently available, metastatic melanoma patients face the bleak prospectof at best, 10 month's survival and a… more
Company: PAUL H. BROOKES PUBLISHING COMPANY, INC. Agency/Program/Year/Phase: HHS / STTR / 2013 / 1
Abstract: DESCRIPTION (provided by applicant): Effective early intervention depends on reliable screening of risk for communication impairments as soon as possible. Established infant communication risk factors include poor attention, gestures, social connectedness,exploratory play, and speech. Although these… more
Company: ARBOR ULTRASOUND TECHNOLOGIES, LLC Agency/Program/Year/Phase: HHS / STTR / 2013 / 1
Abstract: DESCRIPTION (provided by applicant): This proposal describes a novel, low-cost, high-performance compact carotid ultrasound imaging system to meet the clinical point-of-care needs for stenosis assessment based upon consensus practice criteria guidelines. At the same time, this system will meet the… more
Displaying 26 – 50 of 1573 Awards
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