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Displaying 26 – 50 of 196 Awards
Company: MAX MOBILITY Agency/Program/Year/Phase: HHS / SBIR / 2009 / 2
Abstract: DESCRIPTION (provided by applicant): OptiPush Wheelchair Training System Wheelchair users are over twice as likely to be obese as people in the general population. The solution to obesity in the wheelchair user population is the same as it is in the gener al population, a healthy diet and regular… more
Company: SCI-TEC, INC. Agency/Program/Year/Phase: HHS / SBIR / 2009 / 1
Abstract: DESCRIPTION (provided by applicant): The goal of this SBIR project is to develop a new drug discovery platform for screening tyrosine kinase inhibitors. The main innovation of the proposed platform is the use of a multi-enzyme assay, which is able to measu re efficiency and identify inhibition… more
Company: ATOM SCIENCES, INC. Agency/Program/Year/Phase: HHS / SBIR / 2008 / 1
Abstract: DESCRIPTION (provided by applicant): The aim of the proposed research is to develop an enabling technology that will allow development of a molecular diagnostic for identification and discrimination among closely related bacterial species that cause signif icant disease at low microorganism numbers.… more
Company: GENHUNTER CORPORATION Agency/Program/Year/Phase: HHS / SBIR / 2008 / 1
Abstract: DESCRIPTION (provided by applicant): Much efforts in gene expression analysis in the past have been focused mainly on the messenger RNAs (mRNAs), thanks to the availability of Differential Display (DD), SAGE and DNA microarray technologies, which all targ et the poly(A) tails present in most… more
Company: MOLECULAR DESIGN INTERNATIONAL, INC. Agency/Program/Year/Phase: HHS / SBIR / 2008 / 2
Abstract: DESCRIPTION (provided by applicant): MDI 301 is a synthetic retinoid that is similar to all-trans retinoic acid (RA) in its ability to stimulate collagen synthesis and inhibit the major collagen-degrading enzymes in skin. A feature that distinguishes MDI 301 from RA is its lack of irritation when… more
Company: MOLECULAR DESIGN INTERNATIONAL, INC. Agency/Program/Year/Phase: HHS / SBIR / 2008 / 1
Abstract: DESCRIPTION (provided by applicant): MDI-301 is a synthetic retinoid. MDI-301, like RA, induces collagen synthesis and reduces expression of collagen-degrading matrix metalloproteinases in the skin. This agent also induces epidermal thickening. However, un like RA, MDI-301 is non-irritating when… more
Company: Notus Laboratories, Inc. Agency/Program/Year/Phase: HHS / SBIR / 2008 / 1
Abstract: DESCRIPTION (provided by applicant): Our long-term research goal is to develop an ophthalmic, nanofiber-based, biodegradable device that will provide extended release of therapeutic agents to the posterior segment of the eye via transscleral and intravitr eal approaches. This platform device will… more
Company: RXBIO, INC. Agency/Program/Year/Phase: HHS / SBIR / 2008 / 1
Abstract: DESCRIPTION (provided by applicant): Bone marrow and gastrointestinal mucosa are highly sensitive to radiation exposure. Radiation-induced damage to bone marrow and the gastrointestinal tract could be lethal in events such as nuclear accidents or radiation terrorism, depending on radiation doses,… more
Company: SCI-TEC, INC. Agency/Program/Year/Phase: HHS / SBIR / 2008 / 2
Abstract: DESCRIPTION (provided by applicant): The goal of this project is to develop a new highly sensitive and cost effective RNA Bioluminescent Assay (RT-qBLA) for high-throughput detection and quantification of RNA and DNA in biological samples. The assay imple ments the same detection concept known from… more
Company: Third Dimension Technologies Agency/Program/Year/Phase: HHS / SBIR / 2008 / 2
Abstract: DESCRIPTION (provided by applicant): The goal of this Phase II SBIR project is to develop and build an Engineering Demonstration version of a unique and innovative truly three-dimensional (3D) display for use with 3D Medical data and in Medical Telepresenc e applications. There are presently many… more
Company: ATOM SCIENCES, INC. Agency/Program/Year/Phase: HHS / SBIR / 2007 / 1
Abstract: DESCRIPTION (provided by applicant): The aim of this research is to develop a locus-specific DNA amplification process suitable for highly multiplexed detection of pathogenic mycobacteria in environmental samples. Specifically, this project aims to develo p an assay to identify the presence of… more
Company: GENOME EXPLORATION, INC. Agency/Program/Year/Phase: HHS / SBIR / 2007 / 2
Abstract: DESCRIPTION (provided by applicant): Alcohol abuse and its medical consequences have a significant negative impact on society, the economy and our health. Currently, however, no clinically available laboratory test can reliably diagnose excessive alcohol u se throughout the population or predict the… more
Company: MAX MOBILITY Agency/Program/Year/Phase: HHS / SBIR / 2007 / 2
Abstract: DESCRIPTION (provided by applicant): The PVA clinical practice guidelines for preserving upper limb function following spinal cord injury recommends that wheelchair users minimize the force required to complete upper limb tasks, avoid positioning the hand above the shoulder and avoid extreme… more
Company: PATHFINDER THERAPEUTICS Agency/Program/Year/Phase: HHS / SBIR / 2007 / 2
Abstract: DESCRIPTION (provided by applicant): For the past eight years, an image-guided liver surgery system has been developed by engineers and clinicians at several academic institutions, including Vanderbilt University and Washington University in St. Louis. In mid-2004, after initial investigations… more
Company: PROTEIN DISCOVERY, INC. Agency/Program/Year/Phase: HHS / SBIR / 2007 / 2
Abstract: DESCRIPTION (provided by applicant): High Throughput Fractionation and Concentration System for MALDI-MS This Small Business Innovative Research (SBIR) Phase II project aims to build upon the successful work completed in the Phase I feasibility study to op timize and construct a prototype system for… more
Company: RXBIO, INC. Agency/Program/Year/Phase: HHS / SBIR / 2007 / 1
Abstract: DESCRIPTION (provided by applicant): The goal of this Phase I proposal is to perform lead optimization of a novel small molecular radioprotectant based on the Rx100 scaffold. Rx100, a metabolically stabilized analog of phospholipid growth factor lysophosph atidic acid (LPA), has shown promising… more
Company: SCI-TEC, INC. Agency/Program/Year/Phase: HHS / SBIR / 2007 / 1
Abstract: DESCRIPTION (provided by applicant): The goal of this project is to develop a new, highly sensitive, and cost-effective RNA Enzymatic Luminescence Assay (qELA) for high-throughput detection and quantification of microRNA in biological samples. The a ssay implements the same detection concept… more
Company: SCI-TEC, INC. Agency/Program/Year/Phase: HHS / SBIR / 2007 / 2
Abstract: DESCRIPTION (provided by applicant): The goal of this project is to develop a new microarray platform for performing high-multiplexed analysis of RNA and DNA without chemical modification of target molecules for detection. The main innovation of the propos ed approach is the use nanometer-size… more
Company: AMERIGENICS, INC. Agency/Program/Year/Phase: HHS / SBIR / 2006 / 1
Abstract: DESCRIPTION (provided by applicant): The proposed Universal Fingerprinting Chips (UFCs) are microarrays of thousands of oligonucleotide probes designed to interrogate the "sequence space" occupied by essentially any genome or transcriptome. The probe sequences are selected according to specific… more
Company: ATOM SCIENCES, INC. Agency/Program/Year/Phase: HHS / SBIR / 2006 / 1
Abstract: DESCRIPTION (provided by applicant): Project Summary - A new syndrome-based diagnostic system for rapid detection and identification of category B and C priority pathogens is proposed. Phase 1 will focus on V. cholerae genes and genes from similar pathogens. The technique relies upon a… more
Company: GENOME EXPLORATION, INC. Agency/Program/Year/Phase: HHS / SBIR / 2006 / 1
Abstract: DESCRIPTION (provided by applicant): Alcohol abuse and its medical consequences have a significant negative impact on society, the economy and our health. Currently, however, no clinically available laboratory test can reliably diagnose excessive alcohol use throughout the population or predict the… more
Company: MAX MOBILITY Agency/Program/Year/Phase: HHS / SBIR / 2006 / 1
Abstract: DESCRIPTION (provided by applicant): Wheelchair users are over twice as likely to be obese as people in the general population. The solution to obesity in the wheelchair user population is the same as it is in the general population, a healthy diet and regular exercise. The limited availability of… more
Company: MAX MOBILITY Agency/Program/Year/Phase: HHS / SBIR / 2006 / 1
Abstract: DESCRIPTION (provided by applicant): The PVA clinical practice guidelines for preserving upper limb function following spinal cord injury recommends that wheelchair users minimize the force required to complete upper limb tasks, avoid positioning the hand above the shoulder and avoid extreme… more
Company: MOLECULAR DESIGN INTERNATIONAL, INC. Agency/Program/Year/Phase: HHS / SBIR / 2006 / 1
Abstract: DESCRIPTION (provided by applicant): MDI 301 is a synthetic retinoid that is similar to all-trans retinoic acid (RA) in its ability to stimulate collagen synthesis and inhibit the major collagen-degrading enzymes in skin. A major feature that distinguishes MDI 301 from RA is its lack of irritation… more
Company: PATHFINDER THERAPEUTICS Agency/Program/Year/Phase: HHS / SBIR / 2006 / 2
Abstract: DESCRIPTION (provided by applicant): One of the important developments in disease treatment over the past decade has been the development of image-guided procedures. The rise of such systems has also been associated with a contraction of the market with a few companies becoming the dominant players… more
Displaying 26 – 50 of 196 Awards
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