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Displaying 51 – 75 of 196 Awards
Company: PATHFINDER THERAPEUTICS Agency/Program/Year/Phase: HHS / SBIR / 2006 / 1
Abstract: DESCRIPTION (provided by applicant): For the past eight years, an image-guided liver surgery system has been developed by engineers and clinicians at several academic institutions, including Vanderbilt University and Washington University in St. Louis. In mid-2004, after initial investigations… more
Company: PROTEIN DISCOVERY, INC. Agency/Program/Year/Phase: HHS / SBIR / 2006 / 1
Abstract: DESCRIPTION (provided by applicant): We describe a novel fractionation and concentration system for high throughput analysis of low abundance polypetides in serum samples by matrix-assisted laser desoption ionization (MALDI) mass spectrometry (MS). We propose to develop this polypeptide analysis… more
Company: SCI-TEC, INC. Agency/Program/Year/Phase: HHS / SBIR / 2006 / 1
Abstract: DESCRIPTION (provided by applicant): The goal of this project is to develop a new highly sensitive and cost effective Reverse Transcription Quantitative Bioluminescence Assay (RT-qBLA) for high-throughput detection and quantification of large (mRNA) and small (microRNA) RNAs in diverse biological… more
Company: TELESENSORS, INC. Agency/Program/Year/Phase: HHS / SBIR / 2006 / 1
Abstract: DESCRIPTION (provided by applicant): Innovative technologies for sensitive and selective monitoring of alcohol and its metabolites in humans are of continuing importance to the National Institute of Alcoholism and Alcohol Abuse (NIAAA). Although there has been progress in developing real-time,… more
Company: ATOM SCIENCES, INC. Agency/Program/Year/Phase: HHS / SBIR / 2005 / 1
Abstract: DESCRIPTION (provided by applicant): A novel microarray-based system is proposed for diagnosis of tuberculosis and tuberculosis-like respiratory infections. This diagnostic system offers a parallel method to screen clinical samples for the presence of DNA sequences from Mycobacterium tuberculosis,… more
Company: CRYOMAGNETICS, INC. Agency/Program/Year/Phase: HHS / SBIR / 2005 / 2
Abstract: DESCRIPTION (provided by applicant): The development of a cryogen-free, actively-shielded 7.0 T high resolution superconducting magnet for Ion Cyclotron Resonance Fourier Transform Mass Spectrometry (ICR-FTMS) will significantly reduce system operating costs, improve operator safety, and simplify… more
Company: MOLECULAR DESIGN INTERNATIONAL, INC. Agency/Program/Year/Phase: HHS / SBIR / 2005 / 2
Abstract: DESCRIPTION (provided by applicant): This application represents the Phase II version of SBIR grant R43 AR049621 entitled "Non-Irritating Retinoids for the Treatment of Aging Skin". Studies carried out prior to Phase I and during the Phase I portion of this project have demonstrated that a synthetic… more
Company: PATHFINDER THERAPEUTICS Agency/Program/Year/Phase: HHS / SBIR / 2005 / 1
Abstract: DESCRIPTION (provided by applicant): One of the important developments in disease treatment over the past decade has been the development of image-guided procedures. The rise of such systems has also been associated with a contraction of the market with a few companies becoming the dominant players… more
Company: SCI-TEC, INC. Agency/Program/Year/Phase: HHS / SBIR / 2005 / 1
Abstract: DESCRIPTION (provided by applicant): The goal of this project is to develop a new microarray system for performing gene expression analysis directly with total RNA without labeling and reverse transcription to cDNA. Achieving this goal will provide a critical breakthrough and establish a new… more
Company: Third Dimension Technologies Agency/Program/Year/Phase: HHS / SBIR / 2005 / 1
Abstract: DESCRIPTION (provided by applicant): The goal of this Phase I SBIR project is to demonstrate the feasibility of a high-resolution truly three-dimensional (3D) color display for use in Medical data display applications. Such a display would tremendously improve remote (telepresence) medical… more
Company: Atmospheric Glow Technologies Agency/Program/Year/Phase: HHS / SBIR / 2004 / 2
Abstract: DESCRIPTION (provided by applicant): The sterilization of complex medical devices is difficult due to narrow channels and the presence of optics and electronics. Atmospheric Glow Technologies will develop the Steriglow 210 for room temperature sterilization of these devices using the One Atmosphere… more
Company: CELTEK BIOSCIENCE, LLC Agency/Program/Year/Phase: HHS / SBIR / 2004 / 1
Abstract: DESCRIPTION (provided by applicant): The extracellular assemblies of amyloid peptides in the brain play a central role in the pathology and subsequent cognitive decline in Alzheimer's disease (AD). The long-term goal of this application is to develop a novel therapeutic treatment for AD by targeting… more
Company: CRYOMAGNETICS, INC. Agency/Program/Year/Phase: HHS / SBIR / 2004 / 1
Abstract: DESCRIPTION (provided by applicant): The development of a cryogen-free, actively-shielded 7.0 T high-resolution superconducting magnet for Ion Cyclotron Resonance Fourier Transform Mass Spectrometry (ICR-FTMS) will significantly reduce system operating costs and simplify operation. Bio-scientists… more
Company: GENOME EXPLORATION, INC. Agency/Program/Year/Phase: HHS / SBIR / 2004 / 1
Abstract: N/A
Company: GRYPHUS DIAGNOSTICS, LLC Agency/Program/Year/Phase: HHS / SBIR / 2004 / 1
Abstract: DESCRIPTION (provided by applicant): The long-term goal of this project is to develop an effective and rapid in vitro diagnostic (IVD) test for the evaluation of patient vaginal fluid specimens for vulvovaginal candidiasis using secreted aspartyl proteinase (SAP) as a biomarker. Vulvovaginal… more
Company: ADVANCED BREATH DIAGNOSTICS, LLC Agency/Program/Year/Phase: HHS / SBIR / 2003 / 2
Abstract: DESCRIPTION (provided by applicant): Galactosemia is a potentially lethal, but preventable, disease of newborns. In Phase I of this grant, we demonstrated that a 13C-galactose breath test could be used to assess the degree of impairment of whole body galactose oxidation in more than 90 galactosemic… more
Company: ADVANCED BREATH DIAGNOSTICS, LLC Agency/Program/Year/Phase: HHS / SBIR / 2003 / 1
Abstract: DESCRIPTION (provided by applicant): Galactosemia is a potentially lethal, but preventable, disease of newborns. In Phase I of this grant, we demonstrated that a 13C-galactose breath test could be used to assess the degree of impairment of whole body galactose oxidation in more than 90 galactosemic… more
Company: Atmospheric Glow Technologies Agency/Program/Year/Phase: HHS / SBIR / 2003 / 2
Abstract: DESCRIPTION (provided by applicant): Atmospheric Glow Technologies proposes a novel method of cold sterilization and biofilm destruction of medical and dental materials. The effort will use the One Atmosphere Uniform Glow Discharge Plasma (OAUGDP) technology to attack and destroy biofilms, which… more
Company: Atmospheric Glow Technologies Agency/Program/Year/Phase: HHS / SBIR / 2003 / 1
Abstract: DESCRIPTION (provided by applicant): Atmospheric Glow Technologies proposes a novel method of cold sterilization and biofilm destruction of medical and dental materials. The effort will use the One Atmosphere Uniform Glow Discharge Plasma (OAUGDP) technology to attack and destroy biofilms, which… more
Company: ATOM SCIENCES, INC. Agency/Program/Year/Phase: HHS / SBIR / 2003 / 2
Abstract: DESCRIPTION (provided by applicant): The aim of the research project is to further develop the dual hybridization diagnostic genotyping method into a multiplex assay capable of using unlabeled, unamplified DNA as the target. The feasibility of the dual hybridization method was demonstrated in Phase… more
Company: ATOM SCIENCES, INC. Agency/Program/Year/Phase: HHS / SBIR / 2003 / 1
Abstract: DESCRIPTION (provided by applicant): The aim of the research project is to develop a very inexpensive and rapid capacitance measurement technique that can be used as a diagnostic test to identify specific infectious organisms, their resistance to antimicrobial drugs, and their pathogenicity in a… more
Company: ATOM SCIENCES, INC. Agency/Program/Year/Phase: HHS / SBIR / 2003 / 2
Abstract: DESCRIPTION (provided by applicant): The aim of the research project is to develop a very inexpensive and rapid capacitance measurement technique that can be used as a diagnostic test to identify specific infectious organisms, their resistance to antimicrobial drugs, and their pathogenicity in a… more
Company: CELTEK BIOSCIENCE, LLC Agency/Program/Year/Phase: HHS / SBIR / 2003 / 1
Abstract: DESCRIPTION (provided by applicant): Our long-term goal is to develop a novel therapeutic treatment of human prostate cancer (PCA) by sensitizing PCA cells to apoptosis induced by tumor necrosis factor (TNF)-alpha or other cytotoxic agents. Conventional therapeutic treatments of PCA, such as… more
Company: MOLECULAR DESIGN INTERNATIONAL, INC. Agency/Program/Year/Phase: HHS / SBIR / 2003 / 1
Abstract: DESCRIPTION (provided by applicant): Molecular Design International, Inc. (MDI) has designed and synthesized three synthetic retinoids based on the removal of the free carboxylic acid proton and replacement with an ester moiety in 14-all trans retinoic acid (RA), 13-cis retinoic acid (13-cis RA)… more
Company: PROTEIN DISCOVERY, INC. Agency/Program/Year/Phase: HHS / SBIR / 2003 / 1
Abstract: N/A
Displaying 51 – 75 of 196 Awards
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