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Agency:HHS
Company: Labthermics Technologies, Inc. Agency/Program/Year/Phase: HHS / SBIR / 1986 / 1
Abstract: N/A
Company: Labthermics Technologies, Inc. Agency/Program/Year/Phase: HHS / SBIR / 1986 / 1
Abstract: N/A
Company: Laguna Research Laboratory Agency/Program/Year/Phase: HHS / SBIR / 1986 / 1
Abstract: THE PROJECT IS AIMED AT THE DEVELOPMENT OF AN INEXPENSIVE, COMPACT, AND EFFICIENT GENERATOR OF THERAPEUTIC AEROSOLS SUITABLE FOR INHALATION THERAPY FOR ADULTS, INFANTS, AND CHILDREN. THE DEVICE IS EXPECTED TO PRODUCE MONODISPERSE AEROSOLS, WITH FIXED AND KNOWN DROP SIZE, DETERMINED BY THE AEROSOL… more
Company: LARGE SCALE BIOLOGY CORPORATION Agency/Program/Year/Phase: HHS / SBIR / 1986 / 1
Abstract: N/A
Company: Lasergenics Corporation Agency/Program/Year/Phase: HHS / SBIR / 1986 / 1
Abstract: PANCREATIC CARCINOMA NOW RANKS AS THE FOURTH MOST COMMON CAUSE OF CANCER DEATH IN MAN. AT THIS TIME, IT IS EXTREMELYDIFFICULT TO DIAGNOSE UNTIL IT IS AT AN ADVANCED STATE, RESULTING IN A DISMAL 5-YEAR SURVIVAL RATE OF 2 PERCENT. THEREFORE, A METHOD TO DIAGNOSE PANCREATIC CANCER AT AN EARLY STAGE… more
Company: Lasergenics Corporation Agency/Program/Year/Phase: HHS / SBIR / 1986 / 1
Abstract: LASERS ARE BEING APPLIED TO A GROWING NUMBER OF SURGICAL PROCEDURES BECAUSE THEY CAN REDUCE TRAUMA, PROMOTE MORE RAPID HEALING, REDUCE OPERATING TIME, CONSERVE ANESTHESIA, AND REDUCE HOSPITALIZATION TIME AND COST. SURGEONS CURRENTLY MUST UTILIZE MULTIPLE LASER SYSTEMS, EACH OF WHICHHAS LIMITED… more
Company: Lawrence Medical Systems Inc Agency/Program/Year/Phase: HHS / SBIR / 1986 / 1
Abstract: IT IS LAWRENCE MEDICAL SYSTEMS' HYPOTHESIS THAT NONINVASIVE DETERMINATION OF CARDIAC OUTPUT WILL IDENTIFY THE PATHOPHY- SIOLOGIC BASIS OF A PATIENT'S HYPERTENSION. THAT IS, WHETHER THE HYPERTENSION IS DUE TO ELEVATED CARDIAC OUTPUT, INCREASED SYSTEMIC VASCULAR RESISTANCE, OR BOTH. THIS KNOWLEDGE… more
Company: Lawton Scientific Inc. Agency/Program/Year/Phase: HHS / SBIR / 1986 / 2
Abstract: INVESTIGATIONS ARE TO BE CONDUCTED ON A NEW CELL IMMOBILIZATION PROCEDURE TO PRODUCE UNIQUE BIOCATALYSTS USING LATEX COATINGS ON ACTIVATED CARBON. IN CONTRAST TO PREVIOUSLY TRIED METHODS, OUR METHOD GIVES A POROUS SUPPORT ALLOWING RAPID SUBSTRATE AND GAS TRANSFER, HAS A HARD SURFACE TO AVOID… more
Company: Lipid Specialties Inc Agency/Program/Year/Phase: HHS / SBIR / 1986 / 1
Abstract: STUDIES IN THE MEDICAL LITERATURE SINCE THE 1970S HAVE STRONGLY SUGGESTED THAT EICOSAPENTAENOIC ACID (EPA) IS A SIGNIFICANT MODULATOR OF THROMBOXANE AND PROSTAGLANDIN ACTIVITY, PRIMARILY IN ITS ROLE AS A PRECURSOR OF THE 3 CLASS OF THROMBOXANES AND PROSTAGLANDINS. A RECENT 20-YEAR EPIDEMIOLOGICAL… more
Company: Lipid Specialties Inc Agency/Program/Year/Phase: HHS / SBIR / 1986 / 1
Abstract: THE PRIMARY TREATMENT FOR GALLSTONES IS SURGICAL REMOVAL. WITH A 1% MORTALITY RATE AND SUBSTANTIAL HOSPITALIZATION COSTS, A SEARCH FOR LESS EXPENSIVE AND SAFER TREATMENTS FOR GALLSTONE ELIMINATION IS WARRANTED. IT HAS BEEN SHOWN THAT GALLSTONES CONSIST PRIMARILY OF CHOLESTEROL AND THAT THEIR… more
Company: Lipid Specialties Inc Agency/Program/Year/Phase: HHS / SBIR / 1986 / 1
Abstract: THE PREPARATION OF PANCREATIC TISSUE EXTRACTS REQUIRES THE REMOVAL OF FATS-PRIMARILY TRIGLYCERIDES-FROM CRUDE TISSUE. SUCH EXTRACTED PANCREATIC TISSUE IS OF PARAMOUNT IMPORTANCE IN TREATING CYSTIC FIBROSIS PATIENTS WHO SUFFER FROM PANCREATIC INSUFFICIENCY. IN THE PAST, A VARIETY OF ORGANICSOLVENTS… more
Company: Liposome Technology Inc Agency/Program/Year/Phase: HHS / SBIR / 1986 / 2
Abstract: A LIPOSOME BASED SUSTAINED RELEASE DELIVERY SYSTEM FOR I.M. INJECTION OF WATER SOLUBLE DRUGS WAS DEVELOPED USING GENTAMICIN (I) AS A MODEL DRUG. THE PHARMACOKINETIC PROFILE OF (I) IN MICE, BIODEGRADATION OF THE CARRIER AT THE SITE OF INJECTION, AND HISTOLOGICAL EFFECTS WERE INVESTIGATED. THREE TYPES… more
Company: Loats Associates, Inc. Agency/Program/Year/Phase: HHS / SBIR / 1986 / 2
Abstract: THE COMPANY IS CURRENTLY CONTRACTED TO PROVIDE A MICRO COMPUTER BASED MEDICAL IMAGING SYSTEM TO THE JOHNS HOPKINS UNIVERSITY MEDICAL SCHOOL TO BE USED TO ANALYZE PECEPTOR AUTORADIOGRAMS. THE SYSTEM, CONSISTING OF HARDWARE AND SOFTWARE, WILL BE DELIVERED IN FEBRUARY 1984. IT QUANTIFIES OPTICAL… more
Company: London Diagnostics Inc Agency/Program/Year/Phase: HHS / SBIR / 1986 / 1
Abstract: THE AIM OF THIS PROJECT IS TO DEMONSTRATE A SENSITIVE HOMOGENEOUS CHEMILUMINESCENCE IMMUNOASSAY FOR METHOTREXATE USING THE PRINCIPLE OF CHEMILUMINESCENCE ENERGY TRANSFER. THIS WILL LEAD TO A TECHNIQUE FOR THE DETECTION OF ANTI- NEOPLASTIC DRUGS REQUIRING HIGHLY SENSITIVE ASSAYS. THE NEWASSAY WILL BE… more
Company: Lucitron Inc Agency/Program/Year/Phase: HHS / SBIR / 1986 / 1
Abstract: DIAGNOSTIC IMAGING IS CONSTRAINED BY CURRENT DISPLAY TECHNOLOGY. THE IMAGES ARE SMALL AND DISTORTED BY THICK, CURVED FACEPLATES OF CRT MONITORS. A LARGE, FLAT FULL-COLORDISPLAY IS REQUIRED, IDEALLY WITHOUT THE BULK OF CRTS BUT WITH EQUAL OR BETTER IMAGE QUALITY. THIS RESEARCH PROPOSAL IS DIRECTED AT… more
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