Abstract:…results are accurate. This project will investigate error rates from next-generation sequencing technologies in clinically relevant disease genes. This will help us define data quality metrics and technical specifications for a sequencing-based Personal Genome Service(R)… more
Abstract:… empowering consumers to participate in research. At the heart of this mission is the 23andMe research engine, a novel platform for conducting genetic studies that allows individuals to participate in genetic research by enrolling in the company's Personal Genome … more
Abstract:… eczema. In Phase II, we will extend these studies to include additional phenotypes, treatment response, gene-gene, and gene-environment interactions as well as to incorporate additional participants recruited from new customers of the 23andMe Personal Genome Service(R). We… more
Abstract:… responding to the health impacts of climate change. CCHG will support the National Library of Medicine's mission of enabling biomedical research, supporting health care and public health, and promoting healthy behavior by significantly enhancing its information services… more
Abstract:… more than 13 million Medicare beneficiaries. The process has multiple steps that require careful, comprehensiveassessment to adequately determine patients' present needs, anticipate future needs, make appropriate referral decisions, and coordinate follow-up services.… more
Abstract:… for other functions. Another unnecessary cost, estimated at 5 billion in US nursing homes alone, arises from medications that are wasted due to prescription changes and patient turnover. New regulations from the Centers for Medicare and Medicaid Services, effective 1… more
Abstract:…he field of cessation among youth by determining the feasibility of a multi-media Web-based program as a viable and effective solution andshows promise for commercialization of the program by leveraging the incentive structure to local businesses hoping to promote their … more
Abstract:… will be asked to report the results of tests (for example PSA levels), by replying to the message on their mobile phone or by visiting a portal web site. The project will be piloted in a large rural hospital system providing primary and preventive care services, and be… more
Abstract:… dementia (PWD), the SimpleC Companion, and to develop and test a new mobile tablet, the SimpleC Wellness Coach, in the in-home, aging in place market where the overwhelming majority of PWD receive their care. SimpleC's highly personalized human customer service and… more
Abstract:… 300 mers) at a cost lower than the impure DNA fragments of today to unlock thepotential of synthetic biology. We are proposing to make libraries of clonally amplified and sequence verified long oligonucleotides. Our long term objectives are to implement a commercial service of… more
Abstract:… data supports continued development of CS-MNP-products and new patents. It addresses the production of CS- MNP products for preclinical studies and business development for a very large market requiring more precise, higher margin products. These new products and services… more
Abstract:DESCRIPTION (provided by applicant): Nearly half of all college students have a diagnosable mental health problem (Blanco et al., 2008). College counseling centers (CCCs) are faced with increasing demands for services from Universities, students and parents to meet the treatment… more
Abstract:… abatement of common indoor allergens that cause allergic reactions and frequently induceasthma, especially in children. The focus of this project is on the dust mite. Carbonix LLC proposes a Phase I research program, leading to a commercialization of a new service… more
Abstract:… molecule by associating that molecule with similar patterns found in ligands annotated to protein targets. Whereas many commercially available molecules have no target linkage, on average for any given vendor we predict that about T of them do. Aim 1. To develop a service to… more
Abstract:… PMA clearance using our validated assay. Task #3: Prepare and submit a PMA to the FDA. The assay will be sold as a kit, complete with all of the reagents required for the assay. We will provide the diagnostic kit to CLIA labs that are interested in providing the testing … more
Abstract:… System, SCANS, knowledgebase used by our Geriatric Care Managers. The knowledgebase helps our GCM's to prepare comprehensive care plans for elders and their care givers covering 40 care categories. The intent is to expand the knowledge of and coordinate the services… more
Abstract:DESCRIPTION (provided by applicant): Schools are the primary setting within which children receive mental health (MH) services. The effectiveness of MH programs has been repeatedly demonstrated for a wide array of MH problems, including behavioral and emotional disorders,… more
Abstract:… while increasingly burdened by the onset of multiple, chronic, medical conditions and a decline in cognitive abilities. Concurrent with the dramatic increase in the numbers of seniors with disabling conditions, the Medicare system is expected continue to reduce services… more
Abstract:… the capabilities of Acumen LLC's Medicare/Medicaid Research Information Center (MedRIC). To advance the quality of the data available for public policy research, MedRIC facilitates the acquisition of data from the Centers for Medicare and Medicaid Services (CMS) to… more
Abstract:… to expand the capabilities of the Medicare Research Information Center (MedRIC) recently established by Acumen, LLC with support from NIA. Thepurpose of MedRIC is to facilitate the acquisition and linking of data from the Centers for Medicare and Medicaid Services (CMS) to… more
Abstract:…LIC HEALTH RELEVANCE: The proposed program seeks to develop a system that identifies athletes who may have sustained a mild traumatic brain injury while participating in a sporting event. Early injury detection allows for rapid care and optimal medical services… more
Abstract:… and several secondary partners, proposes to expand the prototype hardware/software platform called STeP-UP created in the first phase of this STTR project. We have demonstrated the feasibility of a platform that can easily accommodate hardware and software services with… more
Abstract:…ad continue to find their way into the consumer household. The reason it is so hard to identify and eliminate items containing egregious amounts of lead is that current tests are very expensive to perform and require the involvement of a trained technician or a full service… more
Abstract:…. Recent trends in healthreform and emphasis on prevention of health and behavioral health problems will necessitate the use of better screening and diagnostic tools, particularly for minority groups who previously have had low access to such preventive services. High… more
Abstract:… change intervention, at a fraction of the cost of in-person or group approaches. If proven effective at improving weight loss and glycemic control in a randomized trial, it could become an important component of the standard of care for prediabetics as a stand-alone service… more
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