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Agency:HHS
Year:20122011
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Displaying 26 – 50 of 2397 Awards
Company: KeraNetics, LLC Agency/Program/Year/Phase: HHS / SBIR / 2012 / 2
Abstract: DESCRIPTION (provided by applicant): Although numerous advances have been made in the treatment of severe hemorrhage, current blood plasma substitutes do not address new insights in resuscitation medicine. Research in fluid technologies and vascular response following significant pre-hospital… more
Company: MASSTECH, INC. Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1
Abstract: DESCRIPTION (provided by applicant): Significant increase in the efficiency and speed of electron transfer dissociation (ETD) in tandem mass spectrometry (MS) will have a profound impact on its applications to the entire analytical field of characterization of posttranslational modifications (PTM)… more
Company: MASSTECH, INC. Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1
Abstract: DESCRIPTION (provided by applicant): Increasing efficiency of ion detection in Fourier Transform Mass Spectrometry (FTMS) can have a tremendous impact on its applications in proteomics and entire analytical field. At present, the sensitivity of FTMS instruments is limited by electrical noise of… more
Company: KORONIS BIOMEDICAL TECHNOLOGIES CORPORAT Agency/Program/Year/Phase: HHS / SBIR / 2012 / 2
Abstract: DESCRIPTION (provided by applicant): The objective of this phase II project is to use a new and innovative sensor technology called Doppler velocimetery (DV) for solving the problem of wayfinding indoors for the vision impaired. By performing a Doppler measurement of the floor movement relative to… more
Company: KORONIS BIOMEDICAL TECHNOLOGIES CORPORAT Agency/Program/Year/Phase: HHS / STTR / 2012 / 1
Abstract: DESCRIPTION (provided by applicant): Koronis Biomedical Technologies (KBT) proposes to develop a novel tunneling magnetoresistance (TMR) sensor for use in medical devices. TMR technology delivers improvements in magnetic sensor size, sensitivity, and noiserejection that represent an opportunity to… more
Company: KORONIS BIOMEDICAL TECHNOLOGIES CORPORAT Agency/Program/Year/Phase: HHS / STTR / 2012 / 1
Abstract: DESCRIPTION (provided by applicant): In this Phase I STTR project Koronis Biomedical Technologies (KBT) in close collaboration with the Zelazo Lab at the University of Minnesota proposes to develop an electroencephalography (EEG) based neurocognitive training tool to enable individuals to improve… more
Company: KORONIS BIOMEDICAL TECHNOLOGIES CORPORAT Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1
Abstract: DESCRIPTION (provided by applicant): Sudden cardiac death (SCD) results in approximately 450,000 deaths each year in the United States alone of older adults. Most fatal SCD events are caused by ventricular arrhythmias (ventricular tachycardia and ventricular fibrillation) in patients both with and… more
Company: KORONIS BIOMEDICAL TECHNOLOGIES CORPORAT Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1
Abstract: DESCRIPTION (provided by applicant): Koronis Biomedical Technologies (KBT) proposes to develop a hearing aid with the ability to replay a recent period of audio. The hearing aid will be equipped with an additional memory to temporarily store the recently recorded audio and will have buttons to… more
Company: KORONIS BIOMEDICAL TECHNOLOGIES CORPORAT Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1
Abstract: DESCRIPTION (provided by applicant): In this Phase I research Koronis Biomedical Technologies Corporation (KBT) will construct a system to improve mobility and transportation access for the cognitively impaired. The proposed system is intended to allow thecognitively impaired to use public… more
Company: KORONIS BIOMEDICAL TECHNOLOGIES CORPORAT Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1
Abstract: DESCRIPTION (provided by applicant): Koronis Biomedical Technologies Corporation (KBT) proposes to develop a spirometer device targeted toward home-based monitoring of asthma patients. Spirometry has well established advantages over peak flow meters for the monitoring of pulmonary function in asthma… more
Company: CAPTOZYME, LLC Agency/Program/Year/Phase: HHS / SBIR / 2012 / 2
Abstract: DESCRIPTION (provided by applicant): Kidney stones are a common and painful human health care problem worldwide. Of all stones developed approximately 75% are composed of calcium oxalate. Urinary oxalate is regarded as a driving force for calcium oxalate stone formation, and absorption of dietary… more
Company: SENTIEN BIOTECHNOLOGIES, INC. Agency/Program/Year/Phase: HHS / SBIR / 2012 / 2
Abstract: DESCRIPTION (provided by applicant): The overall goal of this project is to design a clinical protocol for the operation and monitoring of a mesenchymal stem cell (MSC)-coated dialysis device for the treatment of acute renal failure (ARF) in dogs. The project specific aims are: (1) Biomarker-guided… more
Company: SENTIEN BIOTECHNOLOGIES, INC. Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1
Abstract: DESCRIPTION (provided by applicant): The goal of this Phase I project is to develop a cell-coated device for the treatment of acute liver failure. The device harnesses mesenchymal stem cell secretions to provide combined anti-inflammatory and regenerativesupport. The project specific aims are: (1)… more
Company: REGENX BIOSCIENCES, LLC Agency/Program/Year/Phase: HHS / STTR / 2012 / 1
Abstract: DESCRIPTION (provided by applicant): Mucopolysaccharidosis type I (MPS I) is an autosomal recessive storage disease caused by the absence of a-L-iduronidase (IDUA), resulting in systemic accumulation of glycosaminoglycan (GAG) storage materials, hepatosplenomegaly, skeletal dysplasias,… more
Company: REGENX BIOSCIENCES, LLC Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1
Abstract: DESCRIPTION (provided by applicant): The overall goal of this project is to develop a novel gene-based delivery system to treat neovascular age- related macular degeneration (wet AMD), a debilitating ocular disease. AMD is the leading cause of blindness inAmericans over 60 years of age, with wet AMD… more
Company: AccelerEyes LLC Agency/Program/Year/Phase: HHS / SBIR / 2012 / 2
Abstract: DESCRIPTION (provided by applicant): This application is to deliver high-performance, GPU-enabled computation and visualization software tools to neuroscientists. Today, there are an estimated 1.5 million life science MATLAB users, with a substantial portion of those using MATLAB to solve… more
Company: STEMSYNERGY THERAPEUTICS, INC. Agency/Program/Year/Phase: HHS / SBIR / 2012 / 2
Abstract: DESCRIPTION (provided by applicant): StemSynergy Therapeutics Inc. (SSTI) is a biopharmaceutical company focused on the discovery, development, and commercialization of drugs that target pathways fundamental to stem cells and cancer stem cells. The WorldHealth Organization estimates that over 12… more
Company: STEMSYNERGY THERAPEUTICS, INC. Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1
Abstract: DESCRIPTION (provided by applicant): Despite significant advancements in modern medicine with regards to surgery, radiation therapy and imaging of tumors, the survival rate for patients with non-small-cell lung carcinoma (NSCLC) remain almost identical to20 years ago. Current therapies targeting the… more
Company: INARIAN- NEURODIAGNOSTIC Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1
Abstract: DESCRIPTION (provided by applicant): Alzheimer's disease (AD), the most common geriatric dementia, has become a major threat to aging baby boomers and presents one of the leading, long-term economic and health burdens to our society. The estimated cost ofAD in the US for health care and hospice… more
Company: ACCELERATED MEDICAL DIAGNOSTICS, LLC Agency/Program/Year/Phase: HHS / SBIR / 2012 / 2
Abstract: We developed a technology called PlatinDx that, based upon preclinical data, can potentially identify chemoresistance in lung and bladder cancer patients before they receive carboplatin therapy. PlatinDx utilizes tracing of subtherapeutic microdoses of14C-labeled carboplatin with accelerator… more
Company: ACCELERATED MEDICAL DIAGNOSTICS, LLC Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1
Abstract: A. Background Information We developed a technology called PlatinDx that, based upon preclinical data, can potentially identify chemoresistance in breast cancer patients before they receive oxaliplatin therapy. PlatinDx utilizes tracing of subtherapeuticmicrodoses of 14C-labeled oxaliplatin with… more
Company: PULMOKINE, INC. Agency/Program/Year/Phase: HHS / SBIR / 2012 / 2
Abstract: DESCRIPTION (provided by applicant): The purpose of this Phase II project is to develop a new treatment for pulmonary arterial hypertension (PAH) consisting of the inhaled platelet derived growth factor receptor (PDGFR) inhibitor PK10453. PAH is a diseaseof the pulmonary vasculature associated with… more
Company: DIABETOMICS, LLC Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1
Abstract: DESCRIPTION (provided by applicant): The presence of islet-directed auto-immunity and associated circulating auto-antibodies, previously thought to be primarily characteristic of type-1 diabetes mellitus (T1DM), is now apparent in a proportion of individuals with putative type-2 diabetes (T2DM),… more
Company: GOALISTICS, LLC Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1
Abstract: DESCRIPTION (provided by applicant): Craving, when viewed as a compelling desire to consume a potentially harmful substance or to engage in a potentially harmful act, has been increasingly targeted for basic research, clinical assessment, and treatment. The management of cravings is a critical… more
Company: ORAL HEALTH SOLUTIONS, INC. Agency/Program/Year/Phase: HHS / SBIR / 2012 / 2
Abstract: DESCRIPTION (provided by applicant): Dental caries (tooth decay), is the single most common chronic disease of childhood, affecting nearly 6 in 10 children in the United States. Poor oral health is epidemic among all children, but is especially severe among lower income children. Untreated, tooth… more
Displaying 26 – 50 of 2397 Awards
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