Abstract:DESCRIPTION (provided by applicant): The purpose of this research is to determine the efficacy of orally administered recombinant human lactoferrin (rhLF) in Phase II clinical trials in patients with mild to moderate asthma.
Asthma is one of the most prevalent chronic inflammatory diseases in the… more
Abstract:DESCRIPTION (provided by applicant): Alzheimer's disease (AD) is a long-term, debilitating disorder that causes loss of memory and cognitive functions. There is an urgent need for effective therapeutic agents to ameliorate the symptoms of AD. Important molecular drug targets in AD are the… more
Abstract:This Small Business Innovation Research (SBIR) Phase II research project develops the concept of using hand-held, mobile devices to link the physical world to information networks using advanced pattern and symbol recognition technology that will be deployed on the mobile device. The proposed mobile… more
Abstract:DESCRIPTION (provided by applicant): The population of aging adults in the United States is entering a period of rapid growth as baby boomers get older and life expectancy continues to increase. One problem that is significantly affecting their ability to live and function independently is low… more
Abstract:DESCRIPTION (provided by applicant): To address wayfinding difficulties and physical activity among cognitively-impaired older adults, we propose to develop a navigation aid that can be attached to three- and four-wheeled rollators. The navigation aid will provide navigation assistance to the user… more
Abstract:This Small Business Technology Transfer (STTR) Phase I project presents a new, non-contact method for sorting particles by size. The primary objective of Phase I activities is to evaluate the technical and commercial feasibility of a particle sorter based upon Aerodynamic Vectoring. This objective… more
Abstract:Phase I work was targeted at investigation of a meteorological sensing package for unmanned aerial vehicles (UAVs). Much of this work was based upon operational experience gained during Cloud Cap Technology's involvement with numerous meteorological experiments which involved the use of small UAVs.… more
Abstract:DESCRIPTION (provided by applicant): This is a Phase II SBIR proposal for a major extension to Cytel's flagship software, StatXact, to perform small sample exact inference for correlated categorical data. Such data are common in biomedical research, especially in areas such as genetics,… more
Abstract:DESCRIPTION (provided by applicant): The success and sensitivity of DNA detection is limited in important clinical, forensic, and environmental applications due to the presence of complex biological samples, such as blood, which reduce amplification efficiency. Different pre-PCR treatments that are… more
Abstract:ErisTech, a minority owned small certified defense contracting business based in San Diego, proposes a solution that will explore "best of breed" energy collection and storage techniques for surveillance airships in the stratosphere. Phase I work will consist of developing the most efficient power… more
Abstract:DESCRIPTION (provided by applicant): Ischemic stroke is a major source of illness and burden in the U.S. Stroke survivors are at high risk for recurrence, and therefore they are an important group for secondary prevention. However, there are three major gaps of knowledge in stroke survivors that are… more
Abstract:DESCRIPTION (provided by applicant): In the United States, the right to determine if medical tests, procedures or treatments are to be conducted is manifest through the process of informed consent. The doctrine of informed consent specifies that competent individuals have the right to make a "right"… more
Abstract:79633 Although high-resolution geophysical measurements have been proven to be valuable for characterizing the subsurface at contaminated DOE sites, the data are not yet in routine use. The obstacles are twofold: (1) the potential inconsistency between intepretations of geophysical data and… more
Abstract:We propose an SBIR Phase I effort to develop a JP-8 generator that will provide 500 Watts (net) with the initial goals of a weight of no more than 6.8 kg (15 pounds) in a package that occupies no more than 5 liters (305 cu. in.). This development will combine the respective strengths of the two… more
Abstract:US troops are beginning to discover tactical advantages offered by quiet vehicles. This is partially due to the recent deployment of the Stryker. As a result, requests to reduce vehicle noise are becoming more frequent. The HMMWV will be used as a basis for developing an acoustic signature… more
Abstract:As expected, the STTR Phase I investigation confirmed that the Digital Virtual Human (DVH) and Robonaut technologies can be merged, and that haptic and autostereoscopic technologies can be integrated in the robotic control systems, effectively and productively. This feasibility study verified and… more
Abstract:We intend to develop the technology for lightweight composite structure suitable for both cryogenic fuel depot storage as well as human in-space habitat. These will incorporate improved impact technologies for micro-meteor/space debris protection and radiation capable composite technologies. The… more
Abstract:The intent of this proposal is to develop key building block technology for lightweight composite structures suitable for cryogenic fuel depot storage as well as human in-space habitat. The effort will incorporate and expand on previous work by the participants in the cryogenic performance of… more
Abstract:Robotic vehicle applications requires significant information about the nature of the terrain and objects ahead. Spectral and polarization measurements in addition to normal intensity information provides the kind of information needed for real time decision making for robotic vehicle control and… more
Abstract:The overall focus is on developing software to monitor the electrical system aboard a warship. A laboratory facility will be established to model the electrical system of a modern aircraft carrier, in order to faciltate software development, testing, and verification without burdening a national… more
Abstract:This proposal outlines a comprehensive plan to apply the emerging technology of augmented reality (AR) to facilitate a reduction in runway incursions by supporting more natural and direct perception of airport traffic identification, status, and movement patterns. The proposed system will provide… more
Abstract:This Small Business Technology Transfer Phase I project seeks to enhance the current state of-the-art in production line manufacturing training processes with an initial focus on the automotive industry. Human-directed training by other skilled employees and supervisors does not take advantage of… more
Abstract:This Small Business Innovation Research Phase I project aims to investigate the feasibility of developing new compounds capable of utilizing common marker gene expression in transformed cells to control the growth and character of cells in cell culture and live tissue applications. If successful,… more
Abstract:DESCRIPTION (provided by applicant): This SBIR Phase II application proposes to extend an existing multi-tier Internet client-server assessment and diagnostic system ("CliniMetrica(R)-Diagnostica") by improving the current and implementing new diagnostic logic functions. CliniMetrica(R)-Diagnostica… more
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