Abstract:DESCRIPTION (provided by applicant): The purpose of this research is to determine the efficacy of orally administered recombinant human lactoferrin (rhLF) in Phase II clinical trials in patients with mild to moderate asthma.
Asthma is one of the most prevalent chronic inflammatory diseases in the… more
Abstract:DESCRIPTION (provided by applicant): Alzheimer's disease (AD) is a long-term, debilitating disorder that causes loss of memory and cognitive functions. There is an urgent need for effective therapeutic agents to ameliorate the symptoms of AD. Important molecular drug targets in AD are the… more
Abstract:This Small Business Innovation Research (SBIR) Phase II research project develops the concept of using hand-held, mobile devices to link the physical world to information networks using advanced pattern and symbol recognition technology that will be deployed on the mobile device. The proposed mobile… more
Abstract:DESCRIPTION (provided by applicant): The population of aging adults in the United States is entering a period of rapid growth as baby boomers get older and life expectancy continues to increase. One problem that is significantly affecting their ability to live and function independently is low… more
Abstract:Development and evaluation of an expert systems application to function as a context aware, activity analysis, and notification application to improve self-management of people with cognitive disabilities and effectiveness of caregivers
Abstract:DESCRIPTION (provided by applicant): To address wayfinding difficulties and physical activity among cognitively-impaired older adults, we propose to develop a navigation aid that can be attached to three- and four-wheeled rollators. The navigation aid will provide navigation assistance to the user… more
Abstract:DESCRIPTION (provided by applicant):
The time lapse 3D microscope imaging of living cells is widely used in many biomedical research areas. This technique potentially generates hundreds of image volumes in a single experiment, which are critical to the visualization and quantification of… more
Abstract:The Universal Trail Assessment Process (UTAP) and TrailWare, software for UTAP data, were developed to obtain objective trail information. Over 700 people within Federal, State, local and non-profit agencies have been UTAP trained throughout the US. Requiring 9 to 15 person hours per mile of trail… more
Abstract:DESCRIPTION (provided by applicant): There, is a high incidence of overuse injuries among manual wheelchair users. One method to prevent the development or delay the onset of injuries is to reduce the physical demand on the user during wheelchair propulsion. Configuration of the wheelchair can have… more
Abstract:DESCRIPTION (provided by applicant): People with disabilities have increased health risks as a result of a sedentary lifestyle. Limited access to fitness equipment is a primary barrier to physical activity and a significant environmental barrier to the health and well-being of people with… more
Abstract:People with mobility impairments are excluded from trails, shared-use paths, parks and other public areas where barriers are erected to prevent access by motorized trail vehicles (MTVs). To ensure the safety of trail users and the integrity of the natural environment, many recreation and/or… more
Abstract:This Small Business Technology Transfer (STTR) Phase I project presents a new, non-contact method for sorting particles by size. The primary objective of Phase I activities is to evaluate the technical and commercial feasibility of a particle sorter based upon Aerodynamic Vectoring. This objective… more
Abstract:Chameleon Optics was founded on March 10, 1998 in Philadelphia, PA, for the purpose of developing unique devices based on proprietary chromogenic (color-changing) coatings. The company is a resident organization of the University City Science Center, one of the largest and most successful business… more
Abstract:Phase I work was targeted at investigation of a meteorological sensing package for unmanned aerial vehicles (UAVs). Much of this work was based upon operational experience gained during Cloud Cap Technology's involvement with numerous meteorological experiments which involved the use of small UAVs.… more
Abstract:DESCRIPTION (provided by applicant): This is a Phase II SBIR proposal for a major extension to Cytel's flagship software, StatXact, to perform small sample exact inference for correlated categorical data. Such data are common in biomedical research, especially in areas such as genetics,… more
Abstract:DESCRIPTION (provided by applicant): Alcohol consumption is a worldwide public health issue of great significance and studies indicate that adolescent alcohol misuse is on the increase. Research has also shown that variations in alcohol metabolizing enzymes controlled by genetic polymorphisms… more
Abstract:DESCRIPTION (provided by applicant): EDVOTEK, the "company" (www.edvotek.com) has identified a new market for products that will serve as resources for students and parents. The product line which will be marketed as the "Science Path Accelerator(tm)" (SciPac(tm)) is biology based resource which… more
Abstract:In Phase I, EM Photonics demonstrated the viability of using a reconfigurable hardware approach to accelerating the simulation of electronic circuits based on their electromagnetic properties. In Phase II, this technology will be used to create a solver capable of analyzing mixed signal circuits 64… more
Abstract:The overall objective of this Phase II project is to optimize the fabrication procedure associated with the chemical lithography proposed in Phase I to fabricate nanophotonic structures and devices at a fraction of the cost of existing technologies. We plan to use our optimized chemical lithography… more
Abstract:DESCRIPTION (provided by applicant): The ability to accurately measure in vivo tendon forces would have a broad impact on studying tissue properties, advancing assistive technologies, and furthering our scientific understanding of the human neuromuscular control system. Myoelectric prosthetics and… more
Abstract:Identifying a means of accurately simulating the scattering and radiation from large objects and scenes in a reasonable timeframe has been an active area of research for decades. Traditionally, addressing this problem has required either trading accuracy and flexibility for performance or running… more
Abstract:In this proposal we will develop a general method for fabricating 3D polymer based Photonic Crystal structures (PhCs) with engineered defects. The criterions of such a method include the generality of producing various periodic arrangements of 2D, 3D PhCs with or without aperiodic features,… more
Abstract:ErisTech, a minority owned small certified defense contracting business based in San Diego, proposes a solution that will explore "best of breed" energy collection and storage techniques for surveillance airships in the stratosphere. Phase I work will consist of developing the most efficient power… more
Abstract:Successful completion of marketing and logistics research will provide post and pole plants in rural communities, forestland managers, and distribution businesses with critical understanding of the urban retail and wholesale marketplace and how best to position roundwood as a building, woodcraft and… more
Abstract:The project addresses National priorities to concurrently reduce fuel loadings (i.e., remove excess forest biomass) from forested lands and improve the economic and employment sustainability of rural communities. Forestlands adjacent to roads and in the true wildland-urban interface (WUI) are among… more
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