Abstract:In this SBIR effort we will design (Phase I) and demonstrate (Phase II) an integrated silicon electronic-photonic upconversion receiver that when used with our photonic backend will allow for a highly sensitive, real-time, and economical millimeter wave (mmW) imaging system. The development of this… more
Abstract:In this Phase II SBIR effort we will dramatically reduce the size, weight, and power requirements of a passive millimeter wave imaging system based on optical upconversion. To this end, we will integrate custom silicon-germanium low noise amplifiers that have been designed to efficiently couple… more
Abstract:This Small Business Innovation Research Phase I project is focused on developing a one-piece functionally graded hybrid (fiber/particle) reinforced aluminum alloy matrix automobile brake rotor. Composite brake rotors have substantial weight savings potential, but costs and performance have limited… more
Abstract:REL has demonstrated that Squeeze Casting a is viable process for encapsulation of ceramic tiles for Warfighter protection systems. The SBIR Phase 1 has demonstrated that squeeze cast encapsulation can offer the following process attributes: a. Use of low tolerance as-pressed tiles, b. Control of… more
Abstract:ABSTRACT: In this proposal, SK Infrared LLC (SKI), a spin off from the Krishna Infrared Detector (KIND) laboratory at the University of New Mexico, is teaming up with Raytheon Vision System (RVS) to develop a flat top broadband high operating temperature mid wave infrared and long wave infrared… more
Abstract:The Urban Forestry Modeling and Prioritization Tools project addresses the research and tasks necessary for creating cost effective, web-based software that assists urban foresters with strategically selecting planting locations in order to maximize impact on both the environment and local… more
Abstract:This Small Business Innovation Research (SBIR) Phase I project concerns the development of an optical fiber biosensor platform that achieves exceptionally high sensitivity through use of a nanoscale, high refractive index, self-assembled polymer coating on the cladding surface. A rapid, specific,… more
Abstract:ABSTRACT: The extreme toxicity of organophosphate (OP) chemical warfare agents (CWA) is due to their specific, rapid, and irreversible reaction with cholinesterase enzymes. A significant portion of this reactive nature of OP agents is directly due to the unique metabolically active environment… more
Abstract:Dried blood spots (DBS) analysis has many advantages over standard liquid blood sample testing including: small sample size, ease of blood sampling, room temperature storage, minimal storage size requirement, and ease of shipping. Although these advantages are significant, there are still problems… more
Abstract:Agave BioSystems proposed to develop a system of Rapidly Adaptable Nanotherapeutics (RANT) by combining advanced bioformatics, with DNA-based nanoparticles, peptide nucleic acid (PNA) antisense oligonucleotides, and cell permeating peptides (CPPs). Advanced bioinformatics computing will allow for… more
Abstract:One major cause of the widespread of drug-resistant and virulent bacteria pathogen is the horizontal gene transfer of resistance and virulence genes in the form of plasmids. As proof-of concept for this Phase I effort, Agave BioSystems proposes to develop combinatorial therapeutics by inhibiting… more
Abstract:Wounds infected with drug-resistant Gram-negative bacteria can increase morbidity, hospital length of stay and cost. Among these Klebsiella pneumoniae and Pseudomonas aeruginosa have become important causes of concern in military personnel wounded in battlefield. New classes of antimicrobial agents… more
Abstract:With no clinically approved antiviral therapy available for treatment of flavivirus infections, the development of efficient vaccines and antiviral agents for prevention and treatment of infections is an urgent health priority. A combination of structure-based in silico models, in vitro and… more
Abstract:Bacterial enteric pathogens causing travelers"diarrhea (TD) in developing countries include enterotoxigenic E. coli (50%), Camplyobacter jejuni, Shigella sonnei and Shigella flexneri, while Norovirus is a common viral cause. High risk regions for TD include areas where US service members are… more
Abstract:Field testing of water samples is needed for broad and sensitive detection of toxic industrial chemicals, or TICs. The use of unicellular organisms in cell-based detection systems is particularly advantageous both because these organisms have developed a natural ability to respond to environmental… more
Abstract:This Small Business Innovation Research (SBIR) Phase I project proposes to develop a noninvasive intracranial pressure (ICP) monitor based on a pilot clinical study correlating ocular blood pressure and blood flow parameters to ICP. The proposed novel device will combine several standard medical… more
Abstract:The objective of Phase I is the preliminary design, prototype and testing of a 3D spectral imaging system for the characterization and evaluation of viability of engineered tissue for treating war injuries. The purpose is in ensuring tissue viability, maturity, vascularity to know if a construct is… more
Abstract:ABSTRACT: High Energy X-ray computed tomography (CT) is used to inspect and evaluate the integrity of solid rocket motors (SRM"s). The driving purpose of this proposal is to improve the detection of defects in special cases where the defects are obscured due to limitations of the CT images. … more
Abstract:DESCRIPTION (provided by applicant): This research will have a significant and potentially broad impact on reducing blindness and vision loss of Americans. Many predominant eye conditions, associated with blindness and vision loss, disturb and compromise the photoreceptors. This research will enable… more
Abstract:DESCRIPTION (provided by applicant): Missing data and measurement errors are common problems in statistical data analysis. We are interested in experimental and observational studies where there exist missing data and measurement errors problems. Examplesinclude health surveys containing… more
Abstract:This Small Business Innovation Research (SBIR) Phase II project seeks to further quantify the mechanical performance of mycological bio-composites that address the automotive and structural core industries, while concurrently scaling and demonstrating material production. The engineered composites… more
Abstract:This Small Business Innovation Research (SBIR) Phase II project will enable Energetiq Technology, Inc. to develop and commercialize an advanced Open-Path FTIR Spectrometer (OPFTIR) instrument for monitoring of atmospheric gases over extended distances. The Phase II technical goals will be the… more
Abstract:Conversion of lignocellulosic biomass to liquid transportation fuels and bioproducts is a core element of our nations strategy to replace imported oil with renewable domestic resources. Thermo chemical conversion processes typically require feedstocks 5 to 7.5 times drier than the raw materials and… more
Abstract:The Marine Corps in support of the war fighter has identified the need to increase the mobility of the HMMWV platform to conform to the ORD. As operational theaters constantly change and require the HMMWV platform to operate in soils that have a RCI less than the current vehicle VCI the overall… more
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