Abstract:DESCRIPTION (provided by applicant): Acute pesticide poisoning remains a vast health problem in the developed and developing world. Domestically, a 2004 study estimates that 18 of every 100,000 US agricultural workers suffer from acute pesticide poisoningand a 2002 study of California air found… more
Abstract:DESCRIPTION (provided by applicant): The majority of multiple myeloma (MM) patients will initially respond to standard chemotherapy. However, eventually relapse of the disease, associated with a multi-drug resistant phenotype, contributes to poor clinicaloutcomes. Modulation Therapeutics is… more
Abstract:This Small Business Innovation Research Phase I project will further develop a new software package for automatic dimensional analysis of nanomaterials from electron microscopy images. The difficult task of manual dimensional analysis of nanomaterials is a significant barrier to the success of the… more
Abstract:DESCRIPTION (provided by applicant): According to the American Cancer Society, half of all men and one-third of all women in the United States will develop cancer in their lifetime. While chemotherapy has dramatically improved the survival rate of cancer patients, it comes at the cost of severe… more
Abstract:DESCRIPTION (provided by applicant): Preeclampsia, a hypertensive disorder of pregnancy, is a leading cause of maternal and neonatal morbidity and mortality around the world, responsible for approximately 76,000 maternal and 500,000 infant deaths per year.As a heterogeneous and poorly understood… more
Abstract:DESCRIPTION (provided by applicant): Poor medication adherence has a significant negative impact on patients, clinical study outcomes, and the healthcare system in general. As much as 25% of all healthcare costs could be avoided if patients reliably took their prescribed medications. Medication… more
Abstract:The project team is developing a prototype of a web-based gaming intervention for students in kindergarten to grade 2 to learn standard-based concepts in science, technology, engineering, and math. The games will include engaging and interactive simulations, investigations, stories and videos, as… more
Abstract:This Small Business Innovation Research Phase I project seeks to demonstrate ultra high efficiency quantum dot light-emitting diodes (QD-LEDs) using a top-emitting structure and micro-lens array for display applications. Two key challenges will be addressed. First, a novel top-emitting structure… more
Abstract:DESCRIPTION (provided by applicant): Lung cancer is the leading cause of cancer deaths worldwide. The high mortality is in part due to the lack of good tests for early detection and treatment. Our technology diagnoses the presence of cancer via analysis ofthe specific fingerprint of volatile organic… more
Abstract:ABSTRACT: GameSim is proposing the development of a proof-of-concept Tactical Training Rehearsal Environment (TTRE) built upon Prepar3D, a commercial off-the-shelf (COTS), visual simulation platform. Lockheed Martin, the developer of Prepar3D and the prime contractor for the F-22 and F-35, will be… more
Abstract:Forest understory is an under-utilized woody biomass totaling about 300 million dry tons in the southeastern U.S. alone. One percent recovery of this potential source of energy amounts to about 25 billion Btu per year. Traditional forest management practices require controlled understory burning. To… more
Abstract:This proposal details inventive ways for developing affordable reinforced polymer structures with embedded electrical interfaces. Recent developments in the use of advanced composites for rapidly fabricating cylindrical missile shells have shown that it is possible to incorporate complex circuitry… more
Abstract:Onsite wastewater systems are a significant source of nutrient loading to the environment and there is a demand for technologies that remove nutrients at the source. Most desired are passive, low cost systems that can consistently remove ninety percent or greater nitrogen while having low energy… more
Abstract:Unmanned Aerial System (UAS) operation represents a stressful, cognitively challenging domain where operators are routinely subjected to both occupational and combat stressors and performance failures can have catastrophic effects. Effective performance in such conditions has many dimensions,… more
Abstract:PCP Ammunition Company will deliver a family of Lightweight Advanced Polymer Sub-Sonic Ammunition. We will do this by adapting our current family of calibers by decreasing the internal volume and shape of the case to match the optimal performance requirements of the cartridges. This will result in… more
Abstract:PCP Ammunition Company will research the design and development of Lightweight .50 caliber precision ammunition under this SBIR Phase I contract. PCP will concentrate our efforts on several separate criteria in order to improve upon the current .50 caliber round by utilizing PCP"s current… more
Abstract:Orion Solutions is pleased to submit a recently developed nanotechnology based coating to protect the undersea tow cable from corrosion issues identified in solicitation N131-035. Launched in Q2 2012, Ultra-Ever Dry coating and coating process allow use on non-traditional surfaces such as fabrics,… more
Abstract:ABSTRACT: Magic Leap, Inc. proposes to develop a novel full-color, ultra-high resolution microdisplay for pilot Head Mounted Displays (HMDs) incorporating scanning optical fibers. The single mode optical fiber preserves the coherence of the light source, enabling a diffraction-limited spot to form… more
Abstract:DESCRIPTION (provided by applicant): Multiple Sclerosis (MS) is an autoimmune disease that affects the central nervous system (CNS) and results in neurological and clinical disability i number of adults in the US. Leukocyte infiltration and plaques of demyelination in the brain and spinal cord of… more
Abstract:DESCRIPTION (provided by applicant): Type 1 Diabetes (T1D) is thought to result from a breakdown of self-tolerance that is characterized by T cell-mediated destruction of the insulin-producing -cells in the pancreas. Ultimately, glucose metabolism is interrupted, resulting in the development of… more
Abstract:DESCRIPTION (provided by applicant): Upper limb amputation is a major cause of disability and is most effectively treated with a prosthesis. Powered prostheses - controlled by electromyographic (EMG) signals from residual muscles - are a popular and growing treatment option. Significant challenges… more
Abstract:DESCRIPTION (provided by applicant): Bladder cancer (BCa) is among the five most common malignancies worldwide. In the US alone, new BCa cases for 2012 are estimated at 73,500 with estimated deaths at 14,880. At presentation, the majority of bladder tumorsare non-muscle invasive, and can be treated… more
Abstract:DESCRIPTION (provided by applicant): While there is no doubt smoking is a direct causative factor underlying the development of lung cancer, not every smoker develops lung cancer. In fact, only 10-15% of smokers develop this disease, indicating that otherfactors make certain individuals more… more
Abstract:Approximately 178-195 million children world-wide are malnourished. However, only about 3 percent of the 20 million with severe malnutrition receive treatment. Ready to use therapeutic foods (RUTFs) are greatly improving their nutritional status, with success as high as 95%. Animal-derived… more
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