Abstract:DESCRIPTION (provided by applicant): The alarming increase in incidence of infections caused by drug-resistant bacteria has created an urgent need for new antibacterial agents. We are developing a novel class of small molecule antibiotics ( TZUs ) targeting PolC, the replicative DNA polymerase in… more
Abstract:DESCRIPTION (provided by applicant): The American Cancer Society estimates that more than 1.5 million new cancer victims will be diagnosed this year in the U.S., and that ~572,000 Americans will die of cancer in 2011.1 More than 13 million Americans are living today with a history of cancer, and… more
Abstract:This proposed work addresses the needs of a short pulse, tunable and monochromatic extreme ultraviolet and soft X-ray beamline that is table-top, low cost and easy-to-use for advanced material and nano- device studies using photoemission spectroscopy and nano-imaging techniques. The short-pulse and… more
Abstract:This Small Business Innovation Research (SBIR) Phase II project is to develop a prototype for a commercial two-dimensional infrared (2D IR) spectrometer and its associated mid-infrared laser system. One of the most exciting developments in the field of ultrafast spectroscopy in the last decade has… more
Abstract:This project develops a cloud-based system for managing and delivering “on demand” activity prompts to individuals with intellectual disabilities along with a comprehensive, automated reporting system to enable reliable remote notifications to facilitate monitoring of task compliance. Pictures,… more
Abstract:ABSTRACT: Thermal interface materials (TIMs) constitute an essential part of thermal management which is quickly becoming the limiting factor in high power, high functional density, and increasingly small-sized electronics for future U.S. Air Force (AF) platforms. Examples of critical applications… more
Abstract:ABSTRACT: Energy harvesting has emerged as a critical need for many current and future Air Force missions to enable their long endurance requirements. Traditional approaches have focused on harvesting solar and vibration (i.e., via the use of piezoelectric materials) energy. More recently,… more
Abstract:Intelligence, surveillance and reconnaissance (ISR) has become an essential need for the U.S. Warfighter. In support of this need, the use of autonomous vehicles has grown considerably over the past decade. In particular, the use of small unmanned ground vehicles (SUGV) has proven to be invaluable… more
Abstract:DESCRIPTION (provided by applicant): The overarching goal of this project is to move a new, dry powder formulation of Hepatitis-B vaccine on its path to commercialization. In the Phase I SBIR we tested in vitro three Hep-B dry powder formulations of commercially available Shanvac-B and demonstrated… more
Abstract:ABSTRACT: As the Air Force moves toward the deployment of CubeSats and the need for responsive launches, operational Plug-and-Play instruments to monitor the space environment become necessary. The goal of Phase-II is to develop and deliver a prototype for a new UV remote sensing instrument for… more
Abstract:Thermopile infrared linear arrays manufactured using CMOS integrated circuit processes and micro-machining will provide high performance sensing with low manufacturing cost. Black Forest Engineering (BFE) teamed with Case Western Reserve University will d
Abstract:ABSTRACT: This research focuses on the development of a system for producing and imaging ultracold atoms in optical lattice potentials. Utilizing hybrid magnetic and optical atom chip technology, the system will provide a simple and robust means to perform experiments with optical lattice… more
Abstract:This Small Business Innovation Research (SBIR) Phase II project seeks to develop the next generation of atom chips for producing and manipulating ultracold atomic gases (temperatures<1µK). While atom chips developed in Phase I provided only magnetic control, these new hybrid atom chips will be… more
Abstract:This research focuses on the development of a miniature ultrahigh vacuum system for cold-atom-based magnetometry. Comprised of a modular cold-atom source, and high quality optical cell in a double-MOT system, the approach primarily utilizes passive pumping technologies to facilitate sensitive… more
Abstract:ABSTRACT: Current and future space systems will continue to grow in complexity and capabilities, creating a formidable challenge to monitor, maintain, and utilize these systems and manage their growing network of space and related ground-based assets. Integrated System Health Management (ISHM),… more
Abstract:Colorado Engineering, Inc. (CEI) proposes to combine its extensive expertise with embedded hardware and software design with anti-tamper (AT) technology to develop a tamper resistant, heterogeneous, scalable, morphable, reconfigurable/programmable, modular, multiprocessor, embedded computer… more
Abstract:A radar or electronic warfare (EW) system that was primarily digital from the antenna to baseband would offer tremendous flexibility and capability in addition to decreasing the cost, maintenance and ability to upgrade performance. As radars increase in both transmit frequency and bandwidth,… more
Abstract:NASA is seeking innovative structure technologies that will advance expandable modules for orbital and surface based habitats. These secondary structures must increase utilization of the primary pressurized volumes by accommodating hardware, experiments, storage space, and cable routing. The… more
Abstract:ABSTRACT: The Phase II SBIR program aims to fabricate, test and qualify carbon nanotube based thermal interface materials (TIMs) suitable for use on an Air Force spacecraft mission. Traditional TIMs consist of filled epoxies or rubbers that can be hazardous, time-consuming, and difficult to rework… more
Abstract:Radomes are key components of future Air and Missile Defense Radar (AMDR) systems and are aboard almost every surface vessel in the Navy. These structures provide protection for the radar face, but the long-term environmental instability of existing radome materials can interfere with the… more
Abstract:There is a need for transportable alternative energy systems capable of providing renewable electric power. The proposed Portable Array Module (PAM) meets this need, promising a new age of sustainable clean energy production and portability in situations where highly reliable energy sources must be… more
Abstract:ABSTRACT: High-speed inter-satellite links (ISLs) are a key feature to improving satellite communications (SATCOM) bandwidth in support of global military operations. ISLs increase the number of paths in the network which tend to improve aggregate bandwidth, network survivability, and improve the… more
Abstract:A proposed new external pressure measurement data system for rotors and wings will use COTS components and specially designed hardware and software. The new measurement data system consists of two parts; a glove-like surface treatment that contains the pressure measurement devices and wires passing… more
Abstract:Current DIRCM systems are effective against traditional reticle based seeker architectures. They project a modulated signal to confuse the seeker and divert it off its target. Missiles with modern seekers based on FPA imagers are being developed that are highly resistant to current DIRCM systems… more
Abstract:ABSTRACT: Conformal, wideband and low frequency antennas are a persistent source of research and development for military and commercial integrators, particularly airframe integrators. Generally, conformal antennas are either narrow band or inefficient. Low frequency antennas are usually large and… more
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