Abstract:DESCRIPTION (provided by applicant): Current health care modalities for humans diagnosed with either precancerous actinic keratoses or skin cancers (including basal and squamous cell carcinomas) primarily involve surgical excision of the lesions or chemical or photodynamic burning of the affected… more
Abstract:DESCRIPTION (provided by applicant): The purpose of this application is to expand upon our Phase I work and further develop a fully-interactive multimedia (IMM) computer-based HIV/AIDS prevention curricula for adult women with mild intellectual disabilities (ID) (I.Q. approximately 55 through 75).… more
Abstract:Combinatorial methods are proposed to develop advanced Aqueous Oxidation Catalysts (AOCs) with the capability to mineralize organic contaminants present in effluents from current and future primary wastewater treatment processes at temperatures less than 70Â?aC, pressures below 20 psig, and contact… more
Abstract:Planned science instruments require timeofflight (TOF) detectors with subpicosecond resolution, high count rates, and a large number (hundreds of thousands) of parallel channels. Timetodigital converters (TDCs) are effective for TOF measurement. With few exceptions, subnanosecond TDCs have been… more
Abstract:CMOS APS detectors have emerged as an attractive imaging solution to replace CCD technology. They can be very thin, yield good signaltonoise ratio (SNR) at room temperature, and offer the possibility of incorporating inpixel data processing. But despite its potential, APS has demonstrated relatively… more
Abstract:Domestic CMOS imager manufacturing technologies are attractive as a replacement for CCDs but do not yet meet all the requirements of scientific imagers. Their use in tailored scientific imaging applications is hampered by the large wafer sizes and high cost of deepsubmicron fabrication; the low… more
Abstract:To fully utilize thirdgeneration synchrotron sources, the Xray science community needs advanced detectors that are tailored to beamline science. Detectors are not yet available for the fastest bunch modes, and at the fastest operating modes, collection of multiple bunches is required, laser energy… more
Abstract:Flatpanel Xray detector technologies are desired to replace Xray film, but available detector materials have a number of limitations, such as low efficiency, low sensitivity, high noise, small format, high cost, long product development times, and/or expensive infrastructure. Directdetection… more
Abstract:Voxtel proposes a high speed, asynchronous, photon counting receiver for active ranging by unmanned aerial systems (UAS). Sensitivity to single photons is desirable for a low size weight and power (SWAP) UAS-borne active ranging receiver because of the limited laser pulse energy that can be… more
Abstract:DESCRIPTION (provided by applicant): The FDA requires the use of human hepatocytes for preclinical drug testing by pharmaceutical researchers, but unfortunately the supply of these cells is severely limited. Currently, cadaveric donors and surgical liver resection specimens are currently the only… more
Abstract:DESCRIPTION (provided by applicant): Sepsis is a prevalent and life-threatening medical condition characterized by development of a dysregulated inflammatory immune response and associated tissue damage. This dysregulated inflammatory response is initiatedby activation of Toll-Like receptor (TLR)… more
Abstract:In this Phase II research, Blacktoe Medical will design, manufacture and test a finger-worn ultrasound-imaging probe, optimized for Army vascular access requirements. The vascular finger probe will simplify use and reduce the time to learn complicated ultrasound guided procedures. By leveraging… more
Abstract:DESCRIPTION (provided by applicant): Augmentative and alternative communication devices with voice output (also known as Speech Generating Devices, or SGDs) enable individuals to speak by electronic means. Typical users of SGDs are individuals who have suffered from a stroke, traumatic brain injury,… more
Abstract:DESCRIPTION (provided by applicant): Today, arsenic (As) poisoning is one of the major environmental threats worldwide as millions of human beings have been exposed to excessive arsenic through contaminated drinking water. The serious toxicity of arsenic h
as been well documented. Worldwide,… more
Abstract:DESCRIPTION (provided by applicant): Stroke and heart attack are the leading causes of mortality and grave morbidity. The goal of this Fast-Track STTR grant application is to enable preclinical investigation of WE-thrombin, a bioengineered protein C activa
tor enzyme for the treatment of severe,… more
Abstract:Grid computing, the application of many loosely-coupled computers in federation to provide shared resources makes significant compute or storage capabilities accessible to distributed teams of researchers. In doing so, it also poses a challenge: How do distributed teams collaborate effectively… more
With the range and variety of radiation detectors that exist and the continuing threat of a radiological disaster in the future, the need for training of first responders and personnel in the front lines of interdiction is extraordinary and daunting. It is daunting because of… more
Abstract:This Small Business Innovation Research (SBIR) Phase II project aims to develop a robust, high-speed inorganic resist platform to revolutionize the manufacture of semiconductor devices with feature sizes < 30 nm. At present, there is no demonstrated organic or inorganic resist that satisfies all of… more
The human body is a near perfect energy generator. Demand for energy harvesting innovation, along with technology advances in thin film thermoelectric generators and highly efficient DC/DC boost… more
Abstract:DESCRIPTION (provided by applicant): Education Center for Adoptive Parents Online (ECAPO) Adoption has undergone dramatic change in the past 30 years, due largely to the complexity of contemporary adoptive relationships, which increasingly involve internat
ional, multi-ethnic, multi-racial, and… more
Abstract:DESCRIPTION (provided by applicant): Feeding problems are a frequent harbinger of nascent neurological damage and are a major obstacle in transitioning infants from hospital nursery to discharge. Severe problems often require repeated hospitalization and tube feeding. Refractory feeding problems… more
Abstract:The main objective of the proposed Phase II project is to leverage the technology of THz generation in resonantly-pumped quasi-phase-matched (QPM) GaAs structures, jointly developed by Stanford University and Microtech Instruments, Inc., and create a compact and power-efficient commercial THz source… more
Abstract:DESCRIPTION (provided by applicant): The aim of the project in Phase II is to develop and evaluate a stand-alone, Web-based serious game titled Vstreet-G, and to complete the interactive multimedia instruction on money management by adding a component on i
nvestment skills. Emancipation from… more
Abstract:DESCRIPTION (provided by applicant): Alcohol and drug (AOD) abuse by employees causes many costly problems for business and industry including absenteeism, injuries, health insurance claims, loss of productivity, employee morale, theft, and fatalities. The
loss to companies in the United States… more
Abstract:DESCRIPTION (provided by applicant): Depression is one of the most prevalent mental disorders to afflict adults. It seriously impacts role functioning and often takes a recurrent or chronic course. Given the high prevalence and associated impairments, depr
ession has become a major public health… more
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