Abstract:No currently available burn product has shown efficacy in substantially decreasing wound healing time and preventing scar formation. The goals of this Phase II proposal are to expand on the results obtained in the Phase I study that showed that (1) halofuginone inhibited collagen-mediated… more
Abstract:MagiCom proposes to provide a wideband, highly reliable, survivable, high speed, in-flight communications system for communications between fire control and interceptors in an operational fading channel environment using an adaptive and reconfigurable software defined modem concept. Approved for… more
Abstract:Project Summary/Abstract Koronis Biomedical Technology Corporation (KBT) proposes to develop and evaluate a miniature ultra-low power pulse oximeter for long-term wearable monitoring. There continues to be a clinical need for an unobtrusive pulse oximetersensor that is small and can be worn… more
Abstract:DESCRIPTION (provided by applicant): The mission of CarboNix LLC is the clinically effective abatement of common indoor allergens that cause allergic reactions and frequently induce asthma, especially in economically-disadvantaged children. CarboNix LLC proposes a Phase II SBIR research program that… more
Abstract:DESCRIPTION (provided by applicant): This project aims to generate blood tests for: 1. mild cognitive impairment (MCI), and 2. conversion risk from MCI to full-blown Alzheimer's disease (AD). We have reported that systemic footprints, increases in key micro- RNA (miR) levels, are identifiable… more
Abstract:DESCRIPTION (provided by applicant): Severe oxalate-related conditions such as primary hyperoxaluria (PH), secondary hyperoxaluria (SH) (as a result of short bowel syndrome, chronic inflammatory bowel disease, cystic fibrosis, post bariatric, and other malabsorption syndromes), Zellweger spectrum… more
Abstract:DESCRIPTION (provided by applicant): The goal of this Phase IIB SBIR application is to test the Sentien cellular bioreactor product (the Sentinel ) in a first-in-man study to assess safety and preliminary efficacy. Fifteen post-cardiac surgery patients that are diagnosed with acute kidney injury and… more
Abstract:DESCRIPTION (provided by applicant): Non-small cell lung cancer (NSCLC) is the most common lung cancer. Half of NSCLC shows WNT activation, marking poor survival. StemSynergy Therapeutics Inc (SSTI) has identified a family of WNT inhibitors based on a novel chemical scaffold, with our lead molecule… more
Abstract:ABSTRACT: The objective of this project is to move an energy efficient process for the conversion of carbon dioxide and water into syngas, a key feedstock for the production of synthetic chemicals. BENEFIT: If we are successful we will have a new process to convert air water and sunlight into… more
Abstract:NASA's future X-ray astronomy missions will require X-ray optics that have large effective areas, are lightweight, and cost effective. Recent X-ray telescopes, such as the Chandra Observatory, utilized reflectors made from zerodur which were up to 20mm thick. The thickness of these reflectors… more
Abstract:ABSTRACT: The purpose of the project is to develop and deliver an integrated cooling, heating, and power system that operates from multiple energy sources can be easily incorporated onto a building similar to a standard air conditioning system. The objective of the project is to build a prototype… more
Abstract:ABSTRACT: The objective of this sequential Phase II SBIR is to deliver a Technology Readiness Level 6 (TRL-6) airborne HF, VHF and UHF RF direction finding system that is suitable for integration with SUAS and to demonstrate it in a realistic airborne environment against representative signals. … more
Abstract:ABSTRACT: Current Air Force and industry radome designs are time- and resource-exhaustive, and require frequent maintenance and inspection throughout product lifecycle, due to outdated technologies. Typical panels are constructed with one of several joint types mated to the adjoining panel with… more
Abstract:The broader impact/commercial potential of this Small Business Innovation Research (SBIR) Phase II project is an environment resistant inertial measurement unit (eIMU) for commercial/industrial applications. This eIMU is a miniaturized navigation device that will enable enhanced GPS navigation down… more
Abstract:This Small Business Innovation Research Phase II project anticipates bringing forth a disruptive mouth guard technology that answers the urgent need for better dental protection. In the US alone, every year more than 1 million dental injuries occur, resulting in medical costs of roughly $500 million… more
Abstract:The Phase I objective of this SBIR was to develop a nanothermite-based ignition composition to improve the no-fire performance of electro-explosive devices (EEDs). The developed nanoparticulate aluminum/cupric oxide (nACO) ignition composition provided a significant improvement in no-fire… more
Abstract:For spacecraft design and development teams concerned with cost and schedule, the Quick Spacecraft Thermal Analysis Tool (QuickSTAT) is an innovative software suite that will significantly reduce labor costs and effort associated with the design, analysis, and optimization of spacecraft. Unlike… more
Abstract:Fixed wing UAVs such as the Predator, Global Hawk, and Shadow have become invaluable C4ISR and force projection assets. They have acted as force multiplers, have reduced risk to human personnel, and have enabled new tactics, techniques, and procedures (TTPs). Use of Vertical Takeoff and Landing… more
Abstract:ABSTRACT: The production of 3D models from aerial imagery has been an active research area for many years. Given sufficient image texture and a variety of divergent camera viewpoints, camera pose and scene structure are fully recoverable. Further, software for fully reconstructing a scene from an… more
Abstract:Passive microwave sensors aboard satellites provide valuable information regarding weather conditions by measuring atmospheric attenuation over a broad range of frequencies from 0-200 GHz. Additional ground-based sensors are desirable to provide complementary upward looking measurements that can be… more
Abstract:Nuclear power plant construction and life cycle management requires low cost, 3D information to achieve future construction cost goals. TetraVue is developing a high speed, high resolution 3D video camera that can create engineering models automatically, working like any hand- or shoulder-operated… more
Abstract:ABSTRACT: This Small Business Innovation Research Phase II project seeks to further develop an AR coating on high efficiency PV device surface that can enable a reflection loss<3% over the wavelength range from 300 nm to 1800 nm. The proposed effort will optimize the coating design and the… more
Abstract:NAVAIR SBIR Topic N101-041, Development of High Temperature Survivability Coating Materials with Innovative Application Processes, was initiated to address performance shortfalls in coating systems operating in moderate-high temperature environments. The objective was to develop high temperature… more
Abstract:Ballistic and blast protection of both the crew and vital equipment onboard U.S. Navy surface ships and carriers is a critical component in the design of topside structures on these vessels. Materials such as glass, Plexiglas and polyurea are being considered and implemented for protection in these… more
Abstract:The development of a wireless mobile cloud platform that includes dynamic ride matching; utilizing in-vehicle systems and user interface; with supporting connectivity to social networks and HOV/HOT lane tolling infrastructure, will create a critical enhancement to enable an increase in ridesharing… more
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